Agreement between Scheimpflug Camera and the Swept-source Optical Coherence Tomography Measurements in Keratometry and Higher-order Aberrations
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Purpose: To evaluate the compatibility of corneal curvature and astigmatism, and higher-order aberrations (HOAs) measuredby the Scheimpflug camera Pentacam HR and the swept-source optical coherence tomography ANTERION. Methods: This prospective study included normal subjects with no ophthalmic history. Steep keratometry (K), flat K, astigmatismand its axis of the anterior and posterior surfaces, total corneal power, and HOAs using the two instruments werecompared. To compare the mean values of the measurements, a paired t-test was used. Bland-Altman analysis was applied toassess the agreement between the two devices. Results: Fifty-three eyes of 53 subjects were evaluated. There were statistically significant differences for steep K, astigmatism,and vector J0, J45 in the anterior surface and total corneal power between the two devices (p < 0.05). There werealso significant differences in the most of the keratometric values of the posterior corneal surface (p < 0.05) except J0 (p =0.410). Both devices showed strong positive correlations in steep K, flat K, astigmatism (r > 0.81, p < 0.001) with wide rangesof a 95% limit of agreement. Vectoral components were significantly correlated (r > 0.78, p < 0.001) with narrow 95% limit ofagreement, except J45 of the posterior surface (r = 0.39, p = 0.004). In the corneal HOAs, there were statistically significantdifferences in the vertical coma, horizontal trefoil, spherical aberration, and root mean square of each fifth- and sixth-orderZernike coefficient (p = 0.043, p = 0.041, p < 0.001, p < 0.001, and p < 0.001, respectively). Other HOAs showed moderateto strong positive correlations (r > 0.37, p < 0.05). Most HOAs, except for the horizontal trefoil, showed clinically acceptableagreements. The total root mean square of HOAs was not significantly different between the two devices (p = 0.122). Conclusions: Most of the keratometric values cannot be used interchangeably. However, the vectoral component of astigmatismshowed clinically good agreement. Several HOAs have statistically significant differences; however, almost all HOAsshowed acceptable agreements, except for the horizontal trefoil.
Abstract
Purpose: To evaluate the compatibility of corneal curvature and astigmatism, and higher-order aberrations (HOAs) measuredby the Scheimpflug camera Pentacam HR and the swept-source optical coherence tomography ANTERION. Methods: This prospective study included normal subjects with no ophthalmic history. Steep keratometry (K), flat K, astigmatismand its axis of the anterior and posterior surfaces, total corneal power, and HOAs using the two instruments werecompared. To compare the mean values of the measurements, a paired t-test was used. Bland-Altman analysis was applied toassess the agreement between the two devices. Results: Fifty-three eyes of 53 subjects were evaluated. There were statistically significant differences for steep K, astigmatism,and vector J0, J45 in the anterior surface and total corneal power between the two devices (p < 0.05). There werealso significant differences in the most of the keratometric values of the posterior corneal surface (p < 0.05) except J0 (p =0.410). Both devices showed strong positive correlations in steep K, flat K, astigmatism (r > 0.81, p < 0.001) with wide rangesof a 95% limit of agreement. Vectoral components were significantly correlated (r > 0.78, p < 0.001) with narrow 95% limit ofagreement, except J45 of the posterior surface (r = 0.39, p = 0.004). In the corneal HOAs, there were statistically significantdifferences in the vertical coma, horizontal trefoil, spherical aberration, and root mean square of each fifth- and sixth-orderZernike coefficient (p = 0.043, p = 0.041, p < 0.001, p < 0.001, and p < 0.001, respectively). Other HOAs showed moderateto strong positive correlations (r > 0.37, p < 0.05). Most HOAs, except for the horizontal trefoil, showed clinically acceptableagreements. The total root mean square of HOAs was not significantly different between the two devices (p = 0.122). Conclusions: Most of the keratometric values cannot be used interchangeably. However, the vectoral component of astigmatismshowed clinically good agreement. Several HOAs have statistically significant differences; however, almost all HOAsshowed acceptable agreements, except for the horizontal trefoil.
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