Cytomegalovirus Retinitis After Intravitreous Triamcinolone Injection in a Patient with Central Retinal Vein Occlusion
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초록
To report a case of cytomegalovirus (CMV) retinitis after intravitreal injection of triamcinolone acetonide (IVTA). A 77-year-old woman with macular edema due to central retinal vein occlusion (CRVO) developed peripheral retinitis 4 months after IVTA. A diagnostic anterior chamber paracentesis was performed to obtain DNA for a polymerase chain reaction (PCR) test for viral retinitis. The PCR test was positive for CMV DNA. Other tests for infective uveitis and immune competence were negative. Four months after presentation, gancyclovir was intravitreously injected a total of 5 times, and the retinitis resolved completely. CMV retinitis is a rare complication of local immunosuppression with IVTA. It can be managed with timely injection of intravitreal gancyclovir until recovery from local immunosuppression.
Abstract
To report a case of cytomegalovirus (CMV) retinitis after intravitreal injection of triamcinolone acetonide (IVTA). A 77-year-old woman with macular edema due to central retinal vein occlusion (CRVO) developed peripheral retinitis 4 months after IVTA. A diagnostic anterior chamber paracentesis was performed to obtain DNA for a polymerase chain reaction (PCR) test for viral retinitis. The PCR test was positive for CMV DNA. Other tests for infective uveitis and immune competence were negative. Four months after presentation, gancyclovir was intravitreously injected a total of 5 times, and the retinitis resolved completely. CMV retinitis is a rare complication of local immunosuppression with IVTA. It can be managed with timely injection of intravitreal gancyclovir until recovery from local immunosuppression.
참고문헌 (9)
- Wiegand TW, "Cytomegalovirus retinitis", Int Ophthalmol Clin, 46, pp.91~110 (2006)
- Marshall GS, "Cytomegalovirus seroprevalence in women bearing children in Jefferson County, Kentuchy", Am J Med Sci, 305, pp.292~6 (1993)
- Pass RF, "Epidemiology and transmission of cytomegalovirus", J Infect Dis, 152, pp.243~8 (1985)
- Sohn YM, "Cyomegalovirus infection in sexually active adolescents", J Infect Dis, 163, pp.460~3 (1991)
- Crippa F, "Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation", Clin Infect Dis, 32, pp.214~9 (2001)
- Gallant JE, "Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group", J Infect Dis, 166, pp.1223~7 (1992)
- Saidel MA, "Cytomegalovirus retinitis after intravitreous triamcinolone in an immunocompetent patient", Am J of Ophthalmol, 140, pp.1141~3 (2005)
- Rafael L, "Kaiser Cytomegalovirus retinitis after fluocinolone acetonide (RetisertTM) implant", Am J Ophthalmol, 143, pp.334~5 (2007)
- Delfer MN, "Cytomegalovirus retinitis following intravitreal injection of triamcinolone: report of two cases", Acta Ophthalmol Sand, 85, pp.681~3 (2007)
