데스메막각막내피이식술 후 이식편 실패가 온 환자에서의 데스메막각막내피이식술
Repeat Descemet Membrane Endothelial Keratoplasty after Descemet Membrane Endothelial Keratoplasty Graft Failure
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
목적: 데스메막내피각막이식술(Descemet membrane endothelial keratoplasty) 시행 후 이식편 실패가 발생한 환자에게 데스메막내피각막이식술을 재시도하여 성공한 경험을 보고하고자 한다. 증례요약: 47세 여자 환자에게 좌안 푹스 각막내피이상증(Fuchs’ endothelial dystrophy) 진단으로 본원에서 좌안 데스메막내피각막이식술을 시행하였다. 특별한 합병증은 없었으나 수술 6주 후 각막부종 및 수포가 발생하여 갈수록 악화되었으며, 시력 또한 감퇴되어 수술 7개월 후 이식편 실패 진단하에 좌안 데스메막내피각막이식술을 다시 시행하였다. 재수술 후 8개월째 특별한 합병증 없이 각막은 투명하며 최대교정시력 0.6 내외로 유지되고 있다. 결론: 데스메막내피각막이식술 시행 후 이식편 실패가 발생한 환자에서 데스메막내피각막이식술을 재시행하였는데, 수술 중 기존의 데스메막은 어렵지 않게 온전히 제거할 수 있었으며 합병증 없이 성공적인 결과를 얻을 수 있었다.
Abstract
Purpose: To report a case of secondary Descemet membrane endothelial keratoplasty (DMEK) for graft failure after primary DMEK. Case summary: A 47-year-old female underwent primary DMEK in her left eye with a diagnosis of Fuchs’ endothelial dystrophy. At 6 weeks later, corneal stromal edema with epithelial and subepithelial bullae was first observed. From that point on, the condition of the cornea and the visual acuity continued to degrade. After 7 months, a second DMEK procedure (i.e., a repeat DMEK) for graft failure was performed successfully without any complications. Since the second procedure, the cornea has been clear, and the best-corrected visual acuity has remained at 0.6 for 8 months. Conclusions: To manage graft failure after primary DMEK, we performed a second DMEK procedure. The removal of the previous graft was easy, and there were no complications. Thus, repeat DMEK may be a feasible procedure.
참고문헌 (14)
- Melles GR, "Descemet membrane endothelial keratoplasty(DMEK)", Cornea, 25, pp.987~990 (2006)
- Dirisamer M, "Efficacy of Descemet membrane endothelial keratoplasty : clinical outcome of 200 consecutive cases after a learning curve of 25 cases", Arch Ophthalmol, 129, pp.1435~1443 (2011)
- Dirisamer M, "Prevention and management of graft detachment in Descemet membrane endothelial keratoplasty", Arch Ophthalmol, 130, pp.280~291 (2012)
- 한겨레, "데스메막 각막내피이식술 후의 1년 임상결과", 대한안과학회지, 56(10), pp.1489~1496 (2015), 대한안과학회
- Ing JJ, "Ten-year postoperative results of penetrating keratoplasty", Ophthalmology, 105, pp.1855~1865 (1998)
- Rudolph M, "Corneal higher-order aberrations after Descemet’s membrane endothelial keratoplasty", Ophthalmology, 119, pp.528~535 (2012)
- Tourtas T, "Descemet membrane endothelial keratoplasty versus descemet stripping automated endothelial keratoplasty", Am J Ophthalmol, 153, pp.1082~1090 (2012)
- Boisjoly HM, "Risk factors of corneal graft failure", Ophthalmology, 100, pp.1728~1735 (1993)
- Hlinomazová Z, "DMEK(Descemet membrane endothelial keratoplasty)-early and late postoperative complications", Cesk Slov Oftalmol, 67, pp.75~79 (2011)
- Price MO, "Descemet’s membrane endothelial keratoplasty : prospective multicenter study of visual and refractive outcomes and endothelial survival", Ophthalmology, 116, pp.2361~2368 (2009)
- Dapena I, "Learning curve in Descemet’s membrane endothelial keratoplasty : first series of 135 consecutive cases", Ophthalmology, 118, pp.2147~2154 (2011)
- Dapena I, "How to get started with standardized ‘no-touch’ Descemet membrane endothelial keratoplasty (DMEK)", NIIOS, 69~ (2014)
- E.Y. kim, "Effects of trypan blue on corneal endothelial cell viability;Optimal time of Trypan Blue Dye Application to DMEK donor tissue", Acta Ophthalmologica, 95 (2017), Wiley[DOI]
- Baydoun L, "Repeat Descemet membrane endothelial keratoplasty after complicated primary Descemet membrane endothelial keratoplasty", Ophthalmology, 122, pp.8~16 (2015)
