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Characteristic Findings of Optical Coherence Tomography in Retinal Angiomatous Proliferation

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Purpose: To identify the unique pathologic findings of retinal angiomatous proliferation (RAP) in optical coherence tomography (OCT). Methods: Retrospectively, 29 eyes of 25 patients with age-related macular degeneration and complicated RAP were analyzed. All 29 eyes had choroidal neovascularization (CNV) in the area of pigment epithelial detachment (PED) or adjacent to it, which was visible with fluorescein angiography or indocyanine green angiography. Cross-sectional images were obtained by OCT scanning through the CNV lesions. Results: Six distinctive findings of OCT included drusen (100%), inner retinal cyst (80%), outer retinal cyst (68%),fibrovascular PED (84%), serous retinal detachment (40%), and PED (68%). Conclusions: Through analysis of OCT findings, we revealed six different types of lesions distinctive of RAP which may provide helpful diagnostic information for subsequent treatment and predicting the prognosis of RAP.

Abstract

Purpose: To identify the unique pathologic findings of retinal angiomatous proliferation (RAP) in optical coherence tomography (OCT). Methods: Retrospectively, 29 eyes of 25 patients with age-related macular degeneration and complicated RAP were analyzed. All 29 eyes had choroidal neovascularization (CNV) in the area of pigment epithelial detachment (PED) or adjacent to it, which was visible with fluorescein angiography or indocyanine green angiography. Cross-sectional images were obtained by OCT scanning through the CNV lesions. Results: Six distinctive findings of OCT included drusen (100%), inner retinal cyst (80%), outer retinal cyst (68%),fibrovascular PED (84%), serous retinal detachment (40%), and PED (68%). Conclusions: Through analysis of OCT findings, we revealed six different types of lesions distinctive of RAP which may provide helpful diagnostic information for subsequent treatment and predicting the prognosis of RAP.

참고문헌 (26)

  1. Dell’Omo R, "Aqueous humor levels of vascular endothelial growth factor before and after intravitreal bevacizumab in type 3 versus type 1 and 2 neovascularization: a prospective, case-control study", Am J Ophthalmol, 153, pp.155~161 (2012)
  2. Brancato R, "Optical coherence tomography(OCT)angiomatous prolifieration(RAP)in retinal", Eur J Ophthalmol, 12, pp.467~472 (2002)
  3. Rouvas AA, "Angiographic and OCT features of retinal angiomatous proliferation", Eye, 24, pp.1633~1642 (2010)
  4. Yannuzzi LA, "Retinal angiomatous proliferation in age-related macular degeneration", Retina, 21, pp.416~434 (2001)
  5. Hartnett ME, "Classification of retinal pigment epithelial detachments associated with drusen", Graefes Arch Clin Exp Ophthalmol, 230, pp.11~19 (1992)
  6. Kuhn D, "Imaging of chorioretinal anastomoses in vascularized retinal pigment epithelium detachments", Arch Ophthalmol, 113, pp.1392~1398 (1995)
  7. Hartnett ME, "Deep retinal vascular anomalous complexes in advanced age-related macular degeneration", Ophthalmology, 103, pp.2042~2053 (1996)
  8. Slakter JS, "Retinal choroidal anastomoses and occult choroidal neovascularization in age-related macular degeneration", Ophthalmology, 107, pp.742~753 (2000)
  9. Lafaut BA, "Clinicopathological correlation of deep retinal vascular anomalous complex in age related macular degeneration", Br J Ophthalmol, 84, pp.1269~1274 (2000)
  10. Yannuzzi LA, "Digital indocyanine green videoangiography and choroidal neovascularization", Retina, 12, pp.191~223 (1992)
  11. Yannuzzi LA, "Analysis of vascularized pigment epithelial detachments using indocyanine green videoangiography", Retina, 14, pp.99~113 (1994)
  12. Wolf S, "Spectral-domain optical coherence tomography use in macular diseases : a review", Ophthalmologica, 224, pp.333~340 (2010)
  13. Susan BB, "Bressler. Age-related macular degeneration: non-neovascular early AMD, intermediate AMD, and geographic atrophy, In Retina. 5th ed", pp.1161~ (2013), Elsevier
  14. Gass JD, "Serous retinal pigment epithelial detachment with a notch : a sign of occult choroidal neovascularization", Retina, 4, pp.205~220 (1984)
  15. Wolff B, "Outer retinal cysts in age-related macular degeneration", Acta Ophthalmol, 89, pp.496~499 (2011)
  16. Fernandes LH, "The nature of focal areas of hyperfluorescence or hot spots imaged with indocyanine green angiography", Retina, 22, pp.557~568 (2002)
  17. Zacks DN, "Retinal angiomatous proliferation : optical coherence tomographic confirmation of an intraretinal lesion", Arch Ophthalmol, 122, pp.932~933 (2004)
  18. Chan WM, "Half-dose verteporfin photodynamic therapy for acute central serous chorioretinopathy : one-year results of a randomized controlled trial", Ophthalmology, 115, pp.1756~1765 (2008)
  19. Khanifar AA, "Drusen ultrastructure imaging with spectral domain optical coherence tomography in age-related macular degeneration", Ophthalmology, 115, pp.1883~1890 (2008)
  20. Cohen SY, "Prevalence of reticular pseudodrusen in age-related macular degeneration with newly diagnosed choroidal neovascularisation", Br J Ophthalmol, 91, pp.354~359 (2007)
  21. Leveziel N, "Genotypic influences on severity of exudative age-related macular degeneration", Invest Ophthalmol Vis Sci, 51, pp.2620~2625 (2010)
  22. Liakopoulos S, "Quantitative optical coherence tomography findings in various subtypes of neovascular age-related macular degeneration", Invest Ophthalmol Vis Sci, 49, pp.5048~5054 (2008)
  23. Zweifel SA, "Outer retinal tubulation : a novel optical coherence tomography finding", Arch Ophthalmol, 127, pp.1596~1602 (2009)
  24. Doukas J, "Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema", J Cell Physiol, 216, pp.29~37 (2008)
  25. Coscas F, "Optical coherence tomography identification of occult choroidal neovascularization in age-related macular degeneration", Am J Ophthalmol, 144, pp.592~599 (2007)
  26. Sato T, "Correlation of optical coherence tomography with angiography in retinal pigment epithelial detachment associated with age-related macular degeneration", Retina, 24, pp.910~914 (2004)

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