Higher Order Aberrations of the Corneal Surface after Laser Subepithelial Keratomileusis
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Purpose: To evaluate the changes of higher order aberrations (HOAs) before and after laser subepithelialkeratomileusis (LASEK) and to analyze the influence of tear film instability on HOAs of the corneal surfaceafter LASEK. Methods: In this cross-sectional study, 31 patients who underwent LASEK were divided into dry eye (16 patients,32 eyes) and non-dry eye groups (15 patients, 30 eyes). Uncorrected distance visual acuity, sphericalequivalent refraction, ablation depth, tear film parameters and Ocular Surface Disease Index (OSDI) questionnairescores were evaluated in both groups. Total HOA root mean square (RMS), third-order coma, third-ordertrefoil and fourth-order spherical aberration (SA) of the corneal surface immediately and at 10 seconds afterblinking were measured before and after surgery. Results: The total HOA RMS, coma, trefoil and SA significantly increased after LASEK compared withpreoperative values in both groups. In the dry eye group, total HOA RMS, coma and trefoil significantly increasedexcept for SA at 10 seconds after blinking compared with those measured immediately after blinking. In addition, the changes of total HOA RMS, coma and trefoil were negatively correlated with tear film breakuptime (R = -0.420, -0.473 and -0.439, respectively), but positively correlated with OSDI score (R = 0.433,0.499 and 0.532, respectively). In the non-dry eye group, there were no significant differences between HOAsmeasured at 10 seconds after blinking and those measured immediately after blinking. Conclusions: The HOAs including coma, trefoil and SA significantly increased after LASEK. The tear film instabilityin the dry eye can be associated with more deterioration of the optical quality after LASEK, due to moresignificant increase of total HOA RMS, coma and trefoil.
Abstract
Purpose: To evaluate the changes of higher order aberrations (HOAs) before and after laser subepithelialkeratomileusis (LASEK) and to analyze the influence of tear film instability on HOAs of the corneal surfaceafter LASEK. Methods: In this cross-sectional study, 31 patients who underwent LASEK were divided into dry eye (16 patients,32 eyes) and non-dry eye groups (15 patients, 30 eyes). Uncorrected distance visual acuity, sphericalequivalent refraction, ablation depth, tear film parameters and Ocular Surface Disease Index (OSDI) questionnairescores were evaluated in both groups. Total HOA root mean square (RMS), third-order coma, third-ordertrefoil and fourth-order spherical aberration (SA) of the corneal surface immediately and at 10 seconds afterblinking were measured before and after surgery. Results: The total HOA RMS, coma, trefoil and SA significantly increased after LASEK compared withpreoperative values in both groups. In the dry eye group, total HOA RMS, coma and trefoil significantly increasedexcept for SA at 10 seconds after blinking compared with those measured immediately after blinking. In addition, the changes of total HOA RMS, coma and trefoil were negatively correlated with tear film breakuptime (R = -0.420, -0.473 and -0.439, respectively), but positively correlated with OSDI score (R = 0.433,0.499 and 0.532, respectively). In the non-dry eye group, there were no significant differences between HOAsmeasured at 10 seconds after blinking and those measured immediately after blinking. Conclusions: The HOAs including coma, trefoil and SA significantly increased after LASEK. The tear film instabilityin the dry eye can be associated with more deterioration of the optical quality after LASEK, due to moresignificant increase of total HOA RMS, coma and trefoil.
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