A Prospective Study of Anterior Segment Ocular Parameters in Anisometropia
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: The aim of this study was to investigate the differences in anterior segment ocular parameters inanisometropia >1 D. Methods: This study included 202 eyes of 101 subjects ranging from 10 to 40 years of age with anisometropiaof 1 D or more. The subjects were divided into groups according to anisomyopia, anisoastigmatism, andanisohypermetropia. After providing informed consent, each patient underwent a detailed ophthalmologicalexamination including cycloplegic refraction, best-corrected visual acuity, cover test, axial length (AL) measurementusing A-scan ultrasound biometer, keratometry, anterior chamber depth, and central corneal thicknessmeasurement. For each participant, the eye with greater refractive error was compared to the fellow eyevia paired t-tests. Correlations between parameters were studied using the Pearson correlation coefficient. Results: The average age of subjects was 21.7 ± 9.3 years. Of 101 subjects, 31 had anisomyopia; 42 had anisohypermetropia;and 28 had anisoastigmatism. A predisposition toward greater myopia in right eyes was noted inanisomyopia (24 of 31 subjects, 77%). The inter-ocular acuity difference was significant in all three groups (p < 0.01). As the degree of anisometropia increased, there was significant positive correlation in the difference in AL inmyopes (r = 0.863, p < 0.01) and hypermetropes (r = 0.669, p < 0.01) and the difference in corneal curvaturein anisoastigmatism (r = 0.564, p = 0.002) and hypermetropes (r = 0.376, p = 0.014). A significant positive correlationwas also present between the anterior chamber depth difference and refractive difference in hypermetropes(r = 0.359, p = 0.020). Conclusions: This study showed that anisomyopia is correlated only with anterior chamber differences. Anisohypermetropiais correlated with AL differences as well as corneal curvature difference and anterior chamberdepth difference. The amount of anisoastigmatism correlates only with corneal curvature difference.
Abstract
Purpose: The aim of this study was to investigate the differences in anterior segment ocular parameters inanisometropia >1 D. Methods: This study included 202 eyes of 101 subjects ranging from 10 to 40 years of age with anisometropiaof 1 D or more. The subjects were divided into groups according to anisomyopia, anisoastigmatism, andanisohypermetropia. After providing informed consent, each patient underwent a detailed ophthalmologicalexamination including cycloplegic refraction, best-corrected visual acuity, cover test, axial length (AL) measurementusing A-scan ultrasound biometer, keratometry, anterior chamber depth, and central corneal thicknessmeasurement. For each participant, the eye with greater refractive error was compared to the fellow eyevia paired t-tests. Correlations between parameters were studied using the Pearson correlation coefficient. Results: The average age of subjects was 21.7 ± 9.3 years. Of 101 subjects, 31 had anisomyopia; 42 had anisohypermetropia;and 28 had anisoastigmatism. A predisposition toward greater myopia in right eyes was noted inanisomyopia (24 of 31 subjects, 77%). The inter-ocular acuity difference was significant in all three groups (p < 0.01). As the degree of anisometropia increased, there was significant positive correlation in the difference in AL inmyopes (r = 0.863, p < 0.01) and hypermetropes (r = 0.669, p < 0.01) and the difference in corneal curvaturein anisoastigmatism (r = 0.564, p = 0.002) and hypermetropes (r = 0.376, p = 0.014). A significant positive correlationwas also present between the anterior chamber depth difference and refractive difference in hypermetropes(r = 0.359, p = 0.020). Conclusions: This study showed that anisomyopia is correlated only with anterior chamber differences. Anisohypermetropiais correlated with AL differences as well as corneal curvature difference and anterior chamberdepth difference. The amount of anisoastigmatism correlates only with corneal curvature difference.
참고문헌 (32)
- Gawecki M, "Anisometropia and stereopsis", Klin Oczna, 106, pp.561~563 (2004)
- Weakley DR Jr, "The association between nonstrabismic anisometropia, amblyopia, and subnormal binocularity", Ophthalmology, 108, pp.163~171 (2001)
- Weakley DR Jr, "The role of anisometropia in the development of accommodative esotropia", J AAPOS, 5, pp.153~157 (2001)
- O’Donoghue L, "Profile of anisometropia and aniso-astigmatism in children: prevalence and association with age, ocular biometric measures, and refractive status", Invest Ophthalmol Vis Sci, 54, pp.602~608 (2013)
- Huynh SC, "Prevalence and associations of anisometropia and aniso-astigmatism in a population based sample of 6 year old children", Br J Ophthalmol, 90, pp.597~601 (2006)
- Vincent SJ, "Myopic anisometropia: ocular characteristics and aetiological considerations", Clin Exp Optom, 97, pp.291~307 (2014)
- Randleman JB, "Post-laser in-situ keratomileusis ectasia:current understanding and future directions", Curr Opin Ophthalmol, 17, pp.406~412 (2006)
- Devereux JG, "Anterior chamber depth measurement as a screening tool for primary angle-closure glaucoma in an East Asian population", Arch Ophthalmol, 118, pp.257~263 (2000)
- Congdon NG, "Biometry and primary angle-closure glaucoma among Chinese, white, and black populations", Ophthalmology, 104, pp.1489~1495 (1997)
- Olsen T, "Sources of error in intraocular lens power calculation", J Cataract Refract Surg, 18, pp.125~129 (1992)
- Holladay JT, "Standardizing constants for ultrasonic biometry, keratometry, and intraocular lens power calculations", J Cataract Refract Surg, 23, pp.1356~1370 (1997)
- Benjamin WJ, "Borish’s clinical refraction", pp.2~17 (1998), W. B. Saunders
- Troilo D, "Neonatal eye growth and emmetropisation: a literature review", Eye (Lond), 6, pp.154~160 (1992)
- Olsen T, "On the ocular refractive components: the Reykjavik Eye Study", Acta Ophthalmol Scand, 85, pp.361~366 (2007)
- Wong TY, "Variations in ocular biometry in an adult Chinese population in Singapore: the Tanjong Pagar Survey", Invest Ophthalmol Vis Sci, 42, pp.73~80 (2001)
- Goldschmidt E, "Ocular anisometropia and laterality", Acta Ophthalmol Scand, 82, pp.175~178 (2004)
- Linke SJ, "Eye laterality: a comprehensive analysis in refractive surgery candidates", Acta Ophthalmol, 91, pp.e363~e368 (2013)
- Weakley DR, "The association between anisometropia, amblyopia, and binocularity in the absence of strabismus", Trans Am Ophthalmol Soc, 97, pp.987~1021 (1999)
- Dobson V, "Associations between anisometropia, amblyopia, and reduced stereoacuity in a school-aged population with a high prevalence of astigmatism", Invest Ophthalmol Vis Sci, 49, pp.4427~4436 (2008)
- Levi DM, "Visual deficits in anisometropia", Vision Res, 51, pp.48~57 (2011)
- Chen BB, "Anisometropia magnitude and visual deficits in previously untreated anisometropic amblyopia", Int J Ophthalmol, 6, pp.606~610 (2013)
- Tian Y, "Optical and biometric characteristics of anisomyopia in human adults", Ophthalmic Physiol Opt, 31, pp.540~549 (2011)
- Curtin BJ, "The myopias: basic science and clinical management", pp.277~385 (1985), Harper and Row
- Tekin K, "Effect of myopic anisometropia on anterior and posterior ocular segment parameters", Int Ophthalmol, 37, pp.377~384 (2017)
- 김수영, "The Correlation of Differences in the Ocular Component Values with the Degree of Myopic Anisometropia", Korean Journal of Ophthalmology, 27(1), pp.44~47 (2013), 대한안과학회
- Logan NS, "Posterior retinal contour in adult human anisomyopia", Invest Ophthalmol Vis Sci, 45, pp.2152~2162 (2004)
- Goss DA, "Meridional corneal components of myopia progression in young adults and children", Am J Optom Physiol Opt, 64, pp.475~481 (1987)
- Shih YF, "Lens thickness changes among schoolchildren in Taiwan", Invest Ophthalmol Vis Sci, 50, pp.2637~2644 (2009)
- Strang NC, "Hyperopia is predominantly axial in nature", Curr Eye Res, 17, pp.380~383 (1998)
- Demircan S, "The assessment of anterior and posterior ocular structures in hyperopic anisometropic amblyopia", Med Sci Monit, 21, pp.1181~1188 (2015)
- Yuksel N, "Evaluation of anterior segment parameters using the Pentacam in hyperopic anisometropic amblyopic and normal eyes", J AAPOS, 18, pp.248~250 (2014)
- Pediatric Eye Disease Investigator Group, "The clinical profile of moderate amblyopia in children younger than 7years", Arch Ophthalmol, 120, pp.281~287 (2002)