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Clinical Significance of Choroidal Thickness in Eyes with Ocular Ischemic Syndrome

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Purpose: To determine the clinical significance of choroidal thickness and evaluate changes in choroidal thickness over timein eyes affected by ocular ischemic syndrome (OIS). Methods: Medical records of 16 patients diagnosed with OIS between November 2017 and August 2019 were retrospectivelyreviewed. In every nine areas of the Early Treatment Diabetic Retinopathy Study grid, we compared the differences in choroidalthickness between the eyes with OIS and unaffected eyes, and its change in the OIS eyes during the follow-up periodusing swept-source optical coherence tomography. We analyzed the best-corrected visual acuity, intraocular pressure, fluoresceinangiography (FAG) parameters, systemic diseases, and the duration of symptoms. Correlation between FAG parametersand the choroidal thickness value ratio in the OIS eyes and the unaffected eyes, and changes in the choroidal thickness inthe OIS eyes during follow-up were investigated. Results: Median age of the subjects was 67.5 years. In the OIS eyes, all FAG parameters were delayed at the initial examination. Best-corrected visual acuity and intraocular pressure were significantly different between the OIS and unaffected eyes. While the choroidal thickness in every nine areas of Early Treatment Diabetic Retinopathy Study in the OIS eyes was lesserthan the unaffected eyes, the choroidal thickness of inner temporal, outer nasal, and outer temporal area showed statisticallysignificant difference. During follow-up, changes in choroidal thickness of OIS eyes as well as correlation between the FAGparameters and the choroidal thickness value ratio between the OIS eyes and the unaffected eyes were not found to be statisticallysignificant. Conclusions: The choroidal thickness of the eyes with OIS was significantly less compared with the unaffected eyes. Weinferred that choroidal thinning takes place in the early phase of the disease as the changes in choroidal thickness during thefollow-up period were not significant.

Abstract

Purpose: To determine the clinical significance of choroidal thickness and evaluate changes in choroidal thickness over timein eyes affected by ocular ischemic syndrome (OIS). Methods: Medical records of 16 patients diagnosed with OIS between November 2017 and August 2019 were retrospectivelyreviewed. In every nine areas of the Early Treatment Diabetic Retinopathy Study grid, we compared the differences in choroidalthickness between the eyes with OIS and unaffected eyes, and its change in the OIS eyes during the follow-up periodusing swept-source optical coherence tomography. We analyzed the best-corrected visual acuity, intraocular pressure, fluoresceinangiography (FAG) parameters, systemic diseases, and the duration of symptoms. Correlation between FAG parametersand the choroidal thickness value ratio in the OIS eyes and the unaffected eyes, and changes in the choroidal thickness inthe OIS eyes during follow-up were investigated. Results: Median age of the subjects was 67.5 years. In the OIS eyes, all FAG parameters were delayed at the initial examination. Best-corrected visual acuity and intraocular pressure were significantly different between the OIS and unaffected eyes. While the choroidal thickness in every nine areas of Early Treatment Diabetic Retinopathy Study in the OIS eyes was lesserthan the unaffected eyes, the choroidal thickness of inner temporal, outer nasal, and outer temporal area showed statisticallysignificant difference. During follow-up, changes in choroidal thickness of OIS eyes as well as correlation between the FAGparameters and the choroidal thickness value ratio between the OIS eyes and the unaffected eyes were not found to be statisticallysignificant. Conclusions: The choroidal thickness of the eyes with OIS was significantly less compared with the unaffected eyes. Weinferred that choroidal thinning takes place in the early phase of the disease as the changes in choroidal thickness during thefollow-up period were not significant.

참고문헌 (12)

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