Vision-related Quality of Life in Malaysian Children with Threshold and Prethreshold Retinopathy of Prematurity
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: The prevalence of retinopathy of prematurity (ROP) is higher in developing countries compared to developed countries. There is limited data on vision-related quality of life (VRQoL) among children with severe type of ROP in developingcountries. This study evaluated the influence of threshold and prethreshold ROP on VRQoL in Malaysian children. Methods: Multicenter prospective cross-sectional study conducted in three tertiary hospitals in 2018 to 2019. Children lessthan 7 years old with previous ROP diagnosis were recruited. Patients with systemic comorbidities that affected vision ordaily activities were excluded. A parent or guardian completed the Children’s Visual Function Questionnaire (CVFQ) for theassessment of child’s general health, general vision, competence, personality, family impact, and treatment difficulty. Results: Eight were categorized with threshold ROP, 16 with high-risk prethreshold ROP, and 26 with low-risk prethresholdROP. Fifty age-matched controls were also included. Mean visual acuity in logarithm of the minimum angle of resolution was0.46 in the threshold, 0.08 in high-risk prethreshold, and 0.01 in low-risk prethreshold subgroups. Threshold ROP was associatedwith myopia and strabismus, and associated with poor visual acuity compared to prethreshold ROP. Mean total CVFQscore was significantly lower in the ROP group (p < 0.001) compared to the control group. Mean score and all mean subscalescores were significantly lower in the threshold subgroup compared to high-risk and low-risk prethreshold subgroups, withlowest subscale scores on general vision and general health. There was significant association between gestational age, visualacuity of the better eye, family income, and VRQoL (p < 0.05). Conclusions: ROP was associated with lower VRQoL in children born prematurely in Malaysia. The threshold ROP group is themost affected. General vision and health domains are their main difficulties encountered. Gestational age, visual acuity of thebetter eye, and family income affects the VRQoL.
Abstract
Purpose: The prevalence of retinopathy of prematurity (ROP) is higher in developing countries compared to developed countries. There is limited data on vision-related quality of life (VRQoL) among children with severe type of ROP in developingcountries. This study evaluated the influence of threshold and prethreshold ROP on VRQoL in Malaysian children. Methods: Multicenter prospective cross-sectional study conducted in three tertiary hospitals in 2018 to 2019. Children lessthan 7 years old with previous ROP diagnosis were recruited. Patients with systemic comorbidities that affected vision ordaily activities were excluded. A parent or guardian completed the Children’s Visual Function Questionnaire (CVFQ) for theassessment of child’s general health, general vision, competence, personality, family impact, and treatment difficulty. Results: Eight were categorized with threshold ROP, 16 with high-risk prethreshold ROP, and 26 with low-risk prethresholdROP. Fifty age-matched controls were also included. Mean visual acuity in logarithm of the minimum angle of resolution was0.46 in the threshold, 0.08 in high-risk prethreshold, and 0.01 in low-risk prethreshold subgroups. Threshold ROP was associatedwith myopia and strabismus, and associated with poor visual acuity compared to prethreshold ROP. Mean total CVFQscore was significantly lower in the ROP group (p < 0.001) compared to the control group. Mean score and all mean subscalescores were significantly lower in the threshold subgroup compared to high-risk and low-risk prethreshold subgroups, withlowest subscale scores on general vision and general health. There was significant association between gestational age, visualacuity of the better eye, family income, and VRQoL (p < 0.05). Conclusions: ROP was associated with lower VRQoL in children born prematurely in Malaysia. The threshold ROP group is themost affected. General vision and health domains are their main difficulties encountered. Gestational age, visual acuity of thebetter eye, and family income affects the VRQoL.
참고문헌 (25)
- Gerull R, "Incidence of retinopathy of prematurity(ROP)and ROP treatment in Switzerland 2006-2015 : a population-based analysis", Arch Dis Child Fetal Neonatal Ed, 103, pp.F337~42 (2018)
- Ying GS, "Perinatal risk factors for the retinopathy of prematurity in postnatal growth and ROP Study", Ophthalmic Epidemiol, 26, pp.270~278 (2019)
- Isaza G, "Incidence of retinopathy of prematurity and risk factors among premature infants at a neonatal intensive care unit in Canada", J Pediatr Ophthalmol Strabismus, 50, pp.27~32 (2013)
- Shah VA, "Incidence, risk factors of retinopathy of prematurity among very low birth weight infants in Singapore", Ann Acad Med Singap, 34, pp.169~178 (2005)
- Siswanto JE, "Eleven years of retinopathy of prematurity in one neonatal intensive care unit in Jakarta, Indonesia", Arch Dis Child, 103, pp.619~621 (2018)
- Choo MM, "Retinopathy of prematurity in extremely low birth weight infants in Malaysia", J AAPOS, 13, pp.446~449 (2009)
- Kang EY, "Retinopathy of prematurity trends in Taiwan : a 10-year nationwide population study", Invest Ophthalmol Vis Sci, 59, pp.3599~3607 (2018)
- Agarwal K, "Changing patterns of early childhood blinding conditions presenting to a tertiary eye center : the epidemic of retinopathy of prematurity in India", Indian J Ophthalmol, 67, pp.816~818 (2019)
- Isayama T, "The clinical management and outcomes of extremely preterm infants in Japan: past, present, and future", Transl Pediatr, 8, pp.199~211 (2019)
- 하기용, "Bone Cement Augmentation Procedures for Spinal Pathologic Fractures by Multiple Myeloma", Journal of Korean Medical Science, 30(1), pp.88~94 (2015), 대한의학회
- Messa AA, "Vision-related quality of life in children with retinopathy of prematurity", Arq Bras Oftalmol, 78, pp.224~228 (2015)
- Kesarwani P, "Vision-related quality of life in children with treated retinopathy of prematurity", Indian J Ophthalmol, 67, pp.932~935 (2019)
- Adams GG, "ROP in Asia", Eye(Lond), 34, pp.607~608 (2020)
- Petrou S, "Preference-based health-related quality of life outcomes associated with preterm birth : a systematic review and meta-analysis", Pharmacoeconomics, 38, pp.357~373 (2020)
- Birch EE, "Validity and reliability of the Children’s Visual Function Questionnaire (CVFQ)", J AAPOS, 11, pp.473~479 (2007)
- International Committee for the Classification of Retinopathy of Prematurity, "The International Classification of Retinopathy of Prematurity revisited", Arch Ophthalmol, 123, pp.991~999 (2005)
- Mills MD, "Evaluating the Cryotherapy for Retinopathy of Prematurity Study (CRYO-ROP)", Arch Ophthalmol, 125, pp.1276~1281 (2007)
- Early Treatment for Retinopathy of Prematurity Cooperative Group, "Revised indications for the treatment of retinopathy of prematurity: results of the early treatment for retinopathy of prematurity randomized trial", Arch Ophthalmol, 121, pp.1684~1694 (2003)
- Aralikatti AK, "Is ethnicity a risk factor for severe retinopathy of prematurity", Arch Dis Child Fetal Neonatal Ed, 95, pp.F174~F176 (2010)
- Zunaina E, "Malay premature infants with retinopathy of prematurity : risk factors and screening of NDP gene mutation", J Biomed Clin Sci, 2, pp.5~10 (2017)
- Chang KM, "The trend of retinopathy of prematurity in Malaysia from 1992 to 2001 based on a nationwide blind schools study", Asia Pac J Public Health, 27, pp.217~224 (2015)
- Ozyurt G, "Evaluation of maternal attachment, self-efficacy, levels of depression, and anxiety in mothers who have babies diagnosed with retinopathy of prematurity", Ophthalmic Epidemiol, 25, pp.140~146 (2018)
- Holditch-Davis D, "Patterns of distress in African-American mothers of preterm infants", J Dev Behav Pediatr, 30, pp.193~205 (2009)
- Vijayalakshmi P, "Ocular morbidity associated with retinopathy of prematurity in treated and untreated eyes : a review of the literature and data from a tertiary eye-care center in Southern India", Indian Pediatr, 53(Suppl 2), pp.S137~S42 (2016)
- Scher MS, "Physiologic brain dysmaturity in late preterm infants", Pediatr Res, 70, pp.524~528 (2011)