Assessment of Risk Factors Affecting Refractive Outcomes after Phacovitrectomy for Epiretinal Membrane
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Purpose: To investigate factors associated with refractive outcomes after phacovitrectomy for epiretinal membrane (ERM). Methods: Retrospective review of patients undergoing phacovitrectomy for ERM was done. The main outcome measure waspredictive refraction error (PE), defined as observed refraction error – target refraction error, calculated by the SRK/T, Haigis,and SRK II formulae. PE was measured at postoperative 1, 3, and 6 months. Simple and multiple linear regression analysiswere used to evaluate factors associated with PE. Results: A total of 53 eyes of 53 patients were included. The mean PEs at postoperative 1, 3, and 6 months were all negative,implying myopic shift in all patients regardless of the intraocular lens formula used. Haigis formula showed the least myopicshift among the three formulae (p = 0.001, Friedman test). There was no significant difference in PE depending on preoperativecentral macular thickness (CMT) in subgroup analysis. On stepwise multiple linear regression analysis, ERM etiology (β = 0.759,p = 0.004, SRK/T formula; β = 0.733, p = 0.008, Haigis formula; β = 0.933, p < 0.001, SRK II formula), preoperative anteriorchamber depth (β = –0.662, p = 0.013, Haigis formula; β = –0.747, p = 0.003, SRK II formula), and decrease of CMT (β = –0.003,p = 0.025, SRK/T formula) were significantly associated with PE at postoperative 6 months. Conclusions: Myopic shift in PE was observed after combined phacovitrectomy for epiretinal membrane. ERM etiology, preoperativeanterior chamber depth, and decrease of CMT were significantly associated with PE at postoperative 6 months. There was no difference in PE after surgery between the two groups defined by CMT (≥500 and <500 μm).
Abstract
Purpose: To investigate factors associated with refractive outcomes after phacovitrectomy for epiretinal membrane (ERM). Methods: Retrospective review of patients undergoing phacovitrectomy for ERM was done. The main outcome measure waspredictive refraction error (PE), defined as observed refraction error – target refraction error, calculated by the SRK/T, Haigis,and SRK II formulae. PE was measured at postoperative 1, 3, and 6 months. Simple and multiple linear regression analysiswere used to evaluate factors associated with PE. Results: A total of 53 eyes of 53 patients were included. The mean PEs at postoperative 1, 3, and 6 months were all negative,implying myopic shift in all patients regardless of the intraocular lens formula used. Haigis formula showed the least myopicshift among the three formulae (p = 0.001, Friedman test). There was no significant difference in PE depending on preoperativecentral macular thickness (CMT) in subgroup analysis. On stepwise multiple linear regression analysis, ERM etiology (β = 0.759,p = 0.004, SRK/T formula; β = 0.733, p = 0.008, Haigis formula; β = 0.933, p < 0.001, SRK II formula), preoperative anteriorchamber depth (β = –0.662, p = 0.013, Haigis formula; β = –0.747, p = 0.003, SRK II formula), and decrease of CMT (β = –0.003,p = 0.025, SRK/T formula) were significantly associated with PE at postoperative 6 months. Conclusions: Myopic shift in PE was observed after combined phacovitrectomy for epiretinal membrane. ERM etiology, preoperativeanterior chamber depth, and decrease of CMT were significantly associated with PE at postoperative 6 months. There was no difference in PE after surgery between the two groups defined by CMT (≥500 and <500 μm).
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