소아 천식 환자에서 발견된 거대한 점액전 1예
Mucus Plug in a Child with Asthma
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초록
A 7-year-old girl with asthma developed large mucus plug confirmed by bronchoscopic evaluation. Her respiratory failure and concomitant multiple atelectasis were improved after bronchoscopic removal of the mucus plug. Mucus plug is known to frequently occur in children with asthmatic attack, because of exudate accumulation in airway, different profile of mucus in asthmatic conditions and decreased activity of cilia. Despite the conventional concept that mucus plus is managed by chest physiotherapy, large mucus plug in asthma may cause severe respiratory failure with the development of atelectasis which should be removed by bronchoscopy. We report herein a case of large mucus plug that caused atelectasis in a child with asthmatic attack.
Abstract
A 7-year-old girl with asthma developed large mucus plug confirmed by bronchoscopic evaluation. Her respiratory failure and concomitant multiple atelectasis were improved after bronchoscopic removal of the mucus plug. Mucus plug is known to frequently occur in children with asthmatic attack, because of exudate accumulation in airway, different profile of mucus in asthmatic conditions and decreased activity of cilia. Despite the conventional concept that mucus plus is managed by chest physiotherapy, large mucus plug in asthma may cause severe respiratory failure with the development of atelectasis which should be removed by bronchoscopy. We report herein a case of large mucus plug that caused atelectasis in a child with asthmatic attack.
참고문헌 (25)
- Alexander HL, "A Historical account of death from asthma", J Allergy Clin Immunol, 34, pp.305~22 (1963)
- Lucas AM, "Principles underlying ciliary activity in the respiratory tract", Arch Otolaryngol, 20, pp.518~ (1934)
- Richardson PS, "The physical and chemical properties of airway mucus and their relation to airway function", Eur J Respir Dis Suppl, 111, pp.13~5 (1980)
- Rhodin J, "Electron microscopy of the tracheal ciliated mucosa in rat", Z Zellforsch Mikrosk Anat, 44, pp.345~412 (1956)
- Barnett B, "Flow induced by biological mucociliary systems", Ann N Y Acad Sci, 130, pp.891~901 (1966)
- Brody JS, "Mucociliary clearance after lung denervation and bronchial transection", J Appl Physiol, 32, pp.160~4 (1972)
- Macklem PT, "The stability of peripheral airways", Respir Physiol, 8, pp.191~203 (1970)
- Barton AD, "Bronchial secretions and mucociliary clearance. Biochemical characteristics", Arch Intern Med, 131, pp.140~4 (1973)
- List SJ, "Enhancement of the viscosity of mucin by serum albumin", Biochem J, 175, pp.565~71 (1978)
- Verdugo P, "Molecular mechanism of mucin secretion: I. The role of intragranular charge shielding", J Dent Res, 66, pp.506~8 (1987)
- Lopez-Vidriero MT, "Chemical markers of mucous and serum glycoproteins and their relation to viscosity in mucoid and purulent sputum from various hypersecretory diseases", Am Rev Respir Dis, 117, pp.465~77 (1978)
- Barton AD, "Biochemical characteristics affecting the consistency of bronchial secretions", Chest, 63, pp.59~62 (1973)
- Salvato G, "Some histological changes in chronic bronchitis and asthma", Thorax, 23, pp.168~72 (1968)
- Wanner A, "Tracheobronchial mucus: abnormalities related to asthma and its treatment", J Asthma, 18, pp.27~9 (1981)
- Maxwell GM, "The problem of mucus plugging in children with asthma", J Asthma, 22, pp.131~7 (1985)
- Urschel HC, "Mucoid impaction of the bronchi", Ann Thorac Surg, 2, pp.1~16 (1966)
- Glazer HS, "Bronchial impaction in lobar collapse: CT demonstration and pathologic correlation", AJR Am J Roentgenol, 153, pp.485~8 (1989)
- Ryley HC, "Variation in the composition of sputum in chronic chest diseases", Br J Exp Pathol, 49, pp.625~33 (1968)
- Carl GAP, "Plasma exudation and asthma", Lung, 166, pp.1~23 (1988)
- Burbring E, "Acetylcholine and ciliary movement in the gill plates of Mytilus edulis", Proc R Soc Lond B Biol Sci, 141, pp.445~66 (1953)
- Wanner A, "Clinical aspects of mucociliary transport", Am Rev Respir Dis, 116, pp.73~125 (1977)
- Laurenzi GA, "Mucus flow in the mammalian trachea", Aspen Emphysema Conf, 10, pp.27~40 (1967)
- Hirsch SR, "Sputum liquefying agents: a comparative in vitro evaluation", J Lab Clin Med, 74, pp.346~53 (1969)
- Barbato A, "Use of fiberoptic bronchoscopy in asthmatic children with lung collapse", Pediatr Med Chir, 17, pp.253~5 (1995)
- Tapanainen L, "Investigative bronchoscopy and endobronchial biopsy is well tolerated in hyperreactive asthma patients", Respir Med, 96, pp.466~8 (2002)