논문KCI 등재
Prevention of Atopic Asthma by Early Intervention during Childhood: Testable Approaches
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참고문헌
주제분류임상병리학
초록
Abstract
Recent research from a broad range of independent laboratories indicates that the development of persistent atopic asthma is frequently related to potentially preventable events which occur during early childhood. In particular, the combined effects of respiratory viral infections and atopic responses to aeroallergens during infancy, resulting in turn from developmental deficiencies in innate and adaptiveimmune function, appear to play crucial roles in asthma aetiology. If this model for asthma development is valid, then a variety of testable options exist for primary prevention of the disease. A range of these are discussed below.
참고문헌 (59)
- "Drug development strategies for asthma in search of a new paradigm", 5, pp.695~8 (2004)
- "Postnatal maturation of immune competence during infancy and early childhood", 6, pp.59~70 (1995)
- "The development of the immune system during pregnancy and early life", 55, pp.688~97 (2000)
- "Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon?", 14, pp.353~56 (1993)
- "Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10.", 184, pp.539~48 (1996), Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10
- "Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype" (1920)
- "The immunological pregnancy protective effect of progesterone is manifested via controlling cytokine production", pp.348~51 (1996)
- "Prevention of allogeneic fetal rejection by tryptophan catabolism", 281, pp.1191~3 (1998)
- "The role of placental Fas ligand in maintaining immune privilege at maternal-fetal interface", 17, pp.39~44 (1999)
- "Environmental factors and primary T-cell sensitisation to inhalant allergens in infancy reappraisal of the role of infections and air pollution", 6, pp.1~10 (1995)
- "Family size, infection and atopy: the first decade of the hygiene hypothesis", 55, pp.s2~s10 (2000)
- "Heterogeneity in diphtheria-tetanus-acellular pertussis vaccine-specific cellular immunity during infancy relationship to variations in the kinetics of postnatal maturation of systemic Th1 function", pp.80~8
- "Predominance of Th2-promoting dendritic cells in early human pregnancy decidua", pp.514~522
- "Age-related changes in human blood dendritic cell subpopulations", pp.453~7
- "Development of the airway intraepithelial Dendritic Cell network in the rat from class II MHC differential regulation of Ia expression at different levels of the respiratory tract", pp.203~12, McMenamin C
- "Defective regional immunity in the respiratory tract of neonates is attributable to hyporesponsiveness of local Dendritic Cells to activation signals", pp.3517~3524
- "Dendritic cells in the mucosa of the human trachea are not regularly found in the first year of life", pp.427~431
- "Dendritic cell ontogeny as an aetiological factor in respiratory tract diseases in early life", pp.419~20
- "Genetic ‘risk’ for atopy is associated with delayed postnatal maturation of T-cell competence", pp.1093~9
- "Differential patterns of methylation of the IFNg promoter at CpG and non-CpG sites underlie differences in IFNg gene expression between human neonatal and adult CD45RO- T-cells", pp.2820~7
- "High IFN-γ production by CD8+ T cells and early sensitization among infants at high risk of atopy", pp.710~6, Suriyaarachchi D
- "Activation and functional capacity of human neonatal CD4 T cells", pp.1401~8
- "Primary allergic sensitisation to environmental antigens perinatal T-cell priming as a determinant of responder phenotype in adulthood", pp.1297~301
- "Transplacental priming of the human immune system to environmental allergens universal skewing of initial T-cell responses towards the Th-2 cytokine profile", pp.4730~7
- "Functional maturation of CD4+ CD25+ CTLA4+ CD45RA+ T regulatory cells in human neonatal T cell responses to environmental allergens", pp.3084~3092
- "Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire", pp.793~80
- "Development of long term tolerance versus sensitisation to environmental allergens during the perinatal period", pp.782~7
- "A polymorphism in the 5’ - flanking region of the CD14 gene is associated with circulating soluble CD14 levels with total serum IgE", pp.976~83
- "Expression of CD14 and Toll-like receptor 2 in farmers’ and non-farmers’ children", pp.465~6
- "Th-2-polarised immunological memory to inhalant allergens in atopics is established during infancy and early childhood", pp.1261~9
- "Regulation of T-helper cell responses to inhalant allergen during early childhood", pp.1223~31
- "Development of allergen-specific T-cell memory in atopic and normal children"
- "Inverse association between tuberculin responses and atopic disorder", pp.77~9
- "Atopic eczema is associated with delayed maturation of the antibody response to Pneumococcal vaccine", pp.16~9
- "exposure to viruses and respiratory infections in the first year of life", pp.175~80
- "Increased Th1 and Th2 allergen-induced cytokine responses in children with atopic disease", pp.796~802
- "An immunoepidemiological approach to asthma identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children", pp.142~9, Suriyaarachchi D
- "Asthma and wheezing in the first six years of life", pp.133~8
- "The effects of respiratory infections and breastfeeding on childhood asthma", pp.899~905
- "Is the increase in asthma prevalence linked to increase in allergen load? Allergy 1995;50", pp.935~40
- "Early senstization to allergens and development of respiratory symptoms", pp.905~11
- "Longitudinal changes in atopy during a 4-year period Relation to broncial hyperresponsiveness and respiratory symptoms in a population sample of Australian schoolchildren", pp.65~74
- "Interactions between respiratory tract infections and atopy in the aetiology of asthma", pp.538~45
- "Contemporaneous maturation of immunological and respiratory functions during early childhood Implications for development of asthma prevention strategies", pp.16~24
- "Probiotics in primary prevention of atopic disease", pp.1076~9
- "Prophylactic administration of respiratory syncytial virus immune globulin to high-risk infants and young children", pp.1524~30
- "Palivizumab prophylaxis of respiratory syncytial virus disease in 2000~2001 results from The Palivizumab Outcomes Registry", pp.484~9
- "Respiratory outcomes in high-risk children 7 to 10 years after prophylaxis with respiratory syncytial virus immune globulin", pp.627~33
- "Impact of postnatal glucocorticoids on early lung development", pp.881~8
- "Pollen immunotherapy reduces the development of asthma in children with season rhinoconjunctivitis", pp.251~6
- "Sublingual immunotherapy in asthma and rhinoconjunctivitis; systemic review of paediatric literature", pp.620~4
- "Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy", paj(gb), pp.1392~7
- "Immunotherapy with a standardized Dermatophagoides pteronyssinus extract Specific immunotherapy prevents the onset of new sensitizations in children", pp.450~3
- "Prevention of adult asthma by early intervention during childhood potential value of new generation immunomodulatory drugs", pp.700~3
- "Maternal fish oil supplementation in pregnancy reduced interleukin-13 levels in cord blood of infants at high risk of atopy", pp.442~8
- "Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy", pp.1178~84
- "effect of symptoms sensitization and lung function at age 3 years", pp.433~9
- "Sensitization to airborne environmental allergens", pp.957~60
- "Defence against allergic sensitization in the healthy lung the role of inhalation tolerance", pp.255~62, McMenamin C
관련 논문AI추천
Atopy and House Dust Mite Sensitization as Risk Factors for Asthma in Children김경원, 김규언, 김은수, 서주희, 손명현, 송태원, 신정욱연세대학교의과대학 · Yonsei Medical Journal2005 · 제46권 제5호Indoor Allergen Avoidance and AsthmaPeyton A. Eggleston대한천식알레르기학회 · 천식 및 알레르기2006 · 제26권 제1호Intestinal Microbiota and the Development of Allergy in InfantsEduardo Campos, Naoki Shimojo, Shuichi Suzuki, Yoichi Kohno대한천식알레르기학회 · 천식 및 알레르기2007 · 제27권 제4호The Role of Antibiotics in the Development of Atopic DiseasesKoniman R, Van Bever H.P.대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2006 · 제16권 제2호Viral Infections and the Inception and Exacerbation of Asthmajames E. Getn대한천식알레르기학회 · 천식 및 알레르기2005 · 제25권 제2호Effects of Air Pollutants on Childhood Asthma김자경, 김정희, 손병관, 오지은, 이관희, 임대현, 조성일, 홍영철연세대학교의과대학 · Yonsei Medical Journal2005 · 제46권 제2호
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