국내 기무라병의 임상적 특성
Clinical Characteristics of Kimura Disease in Korea
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Background: The Kimura disease, a chronic inflammatory disorder of unknown etiology, is characterized by subcutaneous mass, regional lymphadenopathy, peripheral blood eosinophilia or increased serum immunoglobulin E level. So far, there has been limited information concerning this disease. Objective: To investigate clinical features of Kimura disease in Korea. Method: We retrospectively reviewed 33 patients who had a histologically proven Kimura disease from January 1995to March 2010 at Hospital. Then clinical features and treatment outcomes were evaluated. Result: Of all patients, 28 were male (84.8%), and mean age was 25.2±15.1 years. Involved sites were as follows;preauricular (n=8), upper arm (n=8), retroauricular (n=6),submandibular (n=4), eyelid (n=4), inguinal (n=4), and cervical area (n=4). Peripheral blood eosinophilia was observed in 87.1% of patients. Twenty-seven patients were treated by operation, corticosteroids, or radiation, and the other 6 were just followed without any intervention. Among the 27 patients treated, only 12 have achieved a state of control. Treatment outcomes in terms of size and mass numbers were variable. Conclusion: Kimura disease should be ruled out in young male who shows painless soft tissue swellings with peripheral blood eosinophilia in Korea. The optimal management for Kimura disease needs to be investigated further.
Abstract
Background: The Kimura disease, a chronic inflammatory disorder of unknown etiology, is characterized by subcutaneous mass, regional lymphadenopathy, peripheral blood eosinophilia or increased serum immunoglobulin E level. So far, there has been limited information concerning this disease. Objective: To investigate clinical features of Kimura disease in Korea. Method: We retrospectively reviewed 33 patients who had a histologically proven Kimura disease from January 1995to March 2010 at Hospital. Then clinical features and treatment outcomes were evaluated. Result: Of all patients, 28 were male (84.8%), and mean age was 25.2±15.1 years. Involved sites were as follows;preauricular (n=8), upper arm (n=8), retroauricular (n=6),submandibular (n=4), eyelid (n=4), inguinal (n=4), and cervical area (n=4). Peripheral blood eosinophilia was observed in 87.1% of patients. Twenty-seven patients were treated by operation, corticosteroids, or radiation, and the other 6 were just followed without any intervention. Among the 27 patients treated, only 12 have achieved a state of control. Treatment outcomes in terms of size and mass numbers were variable. Conclusion: Kimura disease should be ruled out in young male who shows painless soft tissue swellings with peripheral blood eosinophilia in Korea. The optimal management for Kimura disease needs to be investigated further.
참고문헌 (30)
- Sun QF, "Kimura disease: review of the literature", Intern Med J, 38, pp.668~72 (2008)
- Kim HT, "Eosinophilic hyperplastic lymphogranuloma, comparison with Mikulicz's disease", Chin Med J, 23, pp.699~700 (1937)
- Kimura T, "On the unusual granulation combined with hyperplastic changes of lymphatic tissue", Trans Soc Pathol Jpn, 37, pp.179~80 (1948)
- Abuel-Haija M, "Kimura disease", Arch Pathol Lab Med, 131, pp.650~651 (2007)
- Chen H, "Kimura disease: a clinicopathologic study of 21 cases", Am J Surg Pathol, 28, pp.505~13 (2004)
- Yuen HW, "Kimura’s disease: a diagnostic and therapeutic challenge", Singapore Med J, 46, pp.179~83 (2005)
- Viswanatha B, "Kimura disease: an unusual cause of head and neck masses. Report of 2 cases", Ear Nose Throat J, 89, pp.87~9 (2010)
- Lee JK, "Kimura disease of the eyelid in an Indian man", Clin Experiment Ophthalmol, 37, pp.412~4 (2009)
- Yazici D, "Kimura disease of the parotid and retroauricular region: a case report", Otolaryngol Head Neck Surg, 133, pp.86~9 (2007)
- Asma A, "Kimura's disease: an unusual cause of cervical tumor", Med J Malaysia, 60, pp.373~6 (2005)
- Wang DY, "Kimura disease: a case report and review of the Chinese literature", Nephron Clin Pract, 111, pp.55~61 (2009)
- 김희영, "비전형적 MR 소견을 보인 위팔 기무라병 1예 보고", 대한영상의학회지, 62(3), pp.277~281 (2010), 대한영상의학회
- 이봉주, "안면 종물과 안와 부종으로 나타난 기무라씨병 1례", 대한이비인후과학회지 두경부외과학, 51(1), pp.108~111 (2008), 대한이비인후과학회
- 변성수, "이하선부에 발생한 Kimura’s disease에 대한 치험례", 대한구강악안면외과학회지, 33(5), pp.554~558 (2007), 대한구강악안면외과학회
- Kuo TT, "Kimura's disease: involvement of regional lymph nodes and distinction from angiolymphoid hyperplasia with eosinophilia", Am J Surg Pathol, 12, pp.843~54 (1988)
- Jang KA, "Angiolymphoid hyperplasia with eosinophilia and Kimura's disease: a clinico-pathologic study in Korea", Korean J Dermatol, 39, pp.309~17 (2001)
- 조철현, "주관절 부위에 발생한 Kimura씨 병 -증례보고-", 대한 견주관절 학회지, 12(1), pp.89~93 (2009), 대한견주관절학회
- Ohta N, "Increase of Th2 and Tc1 cells in patients with Kimura's disease", Auris Nasus Larynx, 14, pp.1~6 (2010)
- 양기영, "Kimura 병 경과관찰 중 발생한 NK", T 세포 림프종 1예, 2007, pp.73(6), 656~660[DOI]
- Kemeny E, "Membranous nephropathy accompanied by HHV8-DNA-positive angiolymphoid hyperplasia of the skin with eosinophilia: lack of HHV8 viral DNA in the kidney biopsy", Clin Nephrol, 61, pp.295~ (2004)
- Nagore E, "Detection of Epstein-Barr virus DNA in a patient with Kimura's disease", Int J Dermatol, 39, pp.618~20 (2000)
- Pitak-Arnnop P, "Head and neck lesions of Kimura's disease: exclusion of human herpesvirus-8 and Epstein-Barr virus by in situ hybridisation and polymerase chain reaction. An immuno histochemical study", J Craniomaxillofac Surg, 38, pp.266~70 (2010)
- Ohta N, "Serum concentrations of eosinophil cationic protein and eosinophils of patients with Kimura's disease", Allergol Int, 56, pp.45~9 (2007)
- Maheut H, "Renal manifestations of Kimura disease", Nephrologie, 19, pp.335~40 (1998)
- Chartapisak W, "Steroid-resistant nephrotic syndrome associated with Kimura's disease", Am J Nephrol, 381, pp.4~ (2002)
- Yamada A, "Membranous glomerulonephritis associated with eosinophilic lymph folliculosis of the skin (Kimura's disease): report of a case and review of the literature", Clin Nephrol, 18, pp.211~5 (1982)
- Kim KJ, "Kimura’s disease on upper arm: a report of 2 cases", J Korean Bone Joint Tumor Soc, 12, pp.78~82 (2006)
- Chang AR, "Outcomes of Kimura's disease after radiotherapy or nonradiotherapeutic treatment modalities", Int J Radiat Oncol Biol Phys, 65, pp.1233~9 (2006)
- Hobeika CM, "Kimura's disease: case report and review of the literature", J Thorac Imaging, 20, pp.298~300 (2005)
- Beyazit Y, "Changing clinical manifestations of a T-peripheral lymphoma: from hypereosinophilic syndrome to questionable Kimura's disease resulting in parotid mass", Leuk Lymphoma, 47, pp.357~60 (2006)