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Kimura Disease Associated with Allergy and Remote Parasite Infection

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참고문헌

주제분류소아과학

초록

Kimura병은 원인 불명의 만성 염증성 질환으로 아시아계 남성에서 호발하며 전형적으로 압통이 없는 두경부 종창 및 말초 호산구, IgE 증가를 동반한다. 좌경부 종창과 우연히 발견된 호산구 증가증을 주소로 내원한 8세 남아를 보고하고자 한다. 환아는 과거 음식물 알레르기가 있었으며 입원시 Cysticercosis IgG 혈청가의 두배상승이 관찰되었다. 수술로 종괴를 제거 후 호산구 증가증은 현격히 감소하였다. 본 증례는 알레르기 및 과거 기생충 감염이 Kimura병의 원인 및 유발 요인이 될 수 있음을 제시하는 바이다.

Abstract

Kimura disease is rare chronic inflammatory disorder of an unknown etiology and it has a predilection for males of Asian descent. It typically presents with non-tender subcutaneous swellings in the head and neck region, peripheral eosinophilia and an elevated immunoglobulin E level. We present here the case of 8-year-old boy with a past history of food allergy, and he developed swelling of the left neck and incidental eosinophilia. Kimura disease was diagnosed on the basis of the clinical and histological findings. The serum IgG titer of cysticercosis was twice the normal level. After surgical excision of the subcutaneous lesion, the patients eosinophilia was dramatically decreased. We suggest that allergy and remote parasite infection may be the causality or a triggering factor for Kimura disease.

참고문헌 (17)

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