심부정맥혈전증이 동반된 Churg-Strauss 증후군 1예
A Case of Churg-Strauss Syndrome Complicated by Deep Vein Thrombosis
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Churg-Strauss syndrome (CSS) is a rare multi-system vasculitis. Patients with CSS are at greater risk of venous thromboembolic events. However, venous thrombosis is rarely reported in patients with CSS in Korea. We report 1 patient with CSS who experienced deep vein thrombosis. A 27- year-old man was admitted to our hospital due to fever, cough, skin rash on both lower extremities, and right leg edema. He was diagnosed with CSS based on a history of asthma, peripheral eosinophilia, transient pulmonary infiltrates on chest radiograph, and extravascular eosinophils in the skin biopsy specimens. After steroid pulse therapy and the first cycle of intravenous pulse cyclophosphamide therapy, right leg edema did not resolve. Venous ultrasonography and CT angiography detected deep vein thrombosis involving the right common iliac, femoral and calf veins. The patient received both anticoagulation therapy and intravenous pulse cyclophosphamide therapy. After 6 months of anticoagulation therapy and the 9 cycles of intravenous pulse cyclophosphamide therapy, deep vein thrombosis completely resolved.
Abstract
Churg-Strauss syndrome (CSS) is a rare multi-system vasculitis. Patients with CSS are at greater risk of venous thromboembolic events. However, venous thrombosis is rarely reported in patients with CSS in Korea. We report 1 patient with CSS who experienced deep vein thrombosis. A 27- year-old man was admitted to our hospital due to fever, cough, skin rash on both lower extremities, and right leg edema. He was diagnosed with CSS based on a history of asthma, peripheral eosinophilia, transient pulmonary infiltrates on chest radiograph, and extravascular eosinophils in the skin biopsy specimens. After steroid pulse therapy and the first cycle of intravenous pulse cyclophosphamide therapy, right leg edema did not resolve. Venous ultrasonography and CT angiography detected deep vein thrombosis involving the right common iliac, femoral and calf veins. The patient received both anticoagulation therapy and intravenous pulse cyclophosphamide therapy. After 6 months of anticoagulation therapy and the 9 cycles of intravenous pulse cyclophosphamide therapy, deep vein thrombosis completely resolved.
참고문헌 (20)
- Churg J, "Allergic granulomatosis, allergic angiitis, and periarteritis nodosa", Am J Pathol, 27, pp.277~301 (1951)
- Somer T, "Thrombo-embolic and vascular complications in vasculitis syndromes", Eur Heart J, 14(Suppl K), pp.24~29 (1993)
- Allenbach Y, "High frequency of venous thromboembolic events in Churg-Strauss syndrome, Wegener's granulomatosis and microscopic polyangiitis but not polyarteritis nodosa: a systematic retrospective study on 1130 patients", Ann Rheum Dis, 68, pp.564~567 (2009)
- Masi AT, "The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis)", Arthritis Rheum, 33, pp.1094~1100 (1990)
- Abril A, "The Churg Strauss syndrome (allergic granulomatous angiitis): review and update", Semin Arthritis Rheum, 33, pp.106~114 (2003)
- Mi Jung Oh, "Churg-Strauss Syndrome: The Clinical Features and Long-term Follow-up of 17 Patients", Journal of Korean Medical Science, 21(2), pp.265~271 (2006), 대한의학회
- Campbell CD, "A case of Budd-Chiari Syndrome presenting in a lady with newly diagnosed Churg-Strauss Syndrome", Rheumatology (Oxford), 46, pp.890~ (2007)
- Garcia G, "Severe venous thromboembolic disease in Churg-Strauss syndrome", Allergy, 60, pp.409~410 (2005)
- Rosenthal G, "Branch retinal vein occlusion in Churg-Strauss syndrome", Clin Experiment Ophthalmol, 30, pp.381~382 (2002)
- Teresa Sartori M, "Cerebral venous thrombosis as a rare onset of Churg-Strauss syndrome", Thromb Haemost, 96, pp.90~92 (2006)
- van Ledden-Klok MJ, "A boy with Churg-Strauss syndrome and thrombosis associated with eosinophilia", Ned Tijdschr Geneeskd, 150, pp.913~917 (2006)
- Ames PR, "Thrombosis in Churg-Strauss syndrome. Beyond vasculitis", Br J Rheumatol, 35, pp.1181~1183 (1996)
- 장태훈, "Budd-Chiari 증후군을 동반한 Churg-Strauss 증후군 1예", 천식 및 알레르기, 27(3), pp.181~185 (2007), 대한천식알레르기학회
- 박준범, "Churg-Strauss 증후군과 연관된 심부정맥혈전증의 카테터유도혈전용해술: 1예 보고", 대한영상의학회지, 62(5), pp.443~446 (2010), 대한영상의학회
- Spencer FA, "The Worcester Venous Thromboembolism study: a population-based study of the clinical epidemiology of venous thromboembolism", J Gen Intern Med, 21, pp.722~727 (2006)
- Cosgriff SW, "Thromboembolic complications associated with ACTH and cortisone therapy", J Am Med Assoc, 147, pp.924~926 (1951)
- Stolz E, "High-dose corticosteroid treatment is associated with an increased risk of developing cerebral venous thrombosis", Eur Neurol, 49, pp.247~248 (2003)
- Cohen P, "Churg-Strauss syndrome with poor-prognosis factors: a prospective multicenter trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in forty-eight patients", Arthritis Rheum, 57, pp.686~693 (2007)
- Ribi C, "Treatment of Churg-Strauss syndrome without poor-prognosis factors: a multicenter, prospective, randomized, open-label study of seventy-two patients", Arthritis Rheum, 58, pp.586~594 (2008)
- Prandoni P, "The long-term clinical course of acute deep venous thrombosis", Ann Intern Med, 125, pp.1~7 (1996)