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항인터루킨 17A 단일클론항체로 치료받은 환자에서 신경매독에 의한 감각신경성 난청

A Case of Sensorineural Hearing Loss Caused by Neurosyphilis in Patient Who Is Treated by Anti-Interleukin 17A Monoclonal Antibody

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주제분류이비인후과학

초록

Syphilis is a sexually transmitted disease caused by Treponema pallidum, which can invadevarious organs. Syphilis can also cause otologic symptoms such as hearing impairment, tinnitusor dizziness and these otologic symptoms can occur at any stage of syphilis and can be associatedwith neurosyphilis. We report here a case of rapid progressive neurosyphilis showinghearing impairment in a patient with ankylosing spondylitis. He was treated with anti-interleukin17A monoclonal antibody. Since syphilis is one of the causes of reversible sensorineuralhearing loss and syphilis infection with immunosuppression can cause progressive hearingloss if patients in immunomodulatory therapy have sensorineural hearing loss, the possibilityof syphilis should be considered.

Abstract

Syphilis is a sexually transmitted disease caused by Treponema pallidum, which can invadevarious organs. Syphilis can also cause otologic symptoms such as hearing impairment, tinnitusor dizziness and these otologic symptoms can occur at any stage of syphilis and can be associatedwith neurosyphilis. We report here a case of rapid progressive neurosyphilis showinghearing impairment in a patient with ankylosing spondylitis. He was treated with anti-interleukin17A monoclonal antibody. Since syphilis is one of the causes of reversible sensorineuralhearing loss and syphilis infection with immunosuppression can cause progressive hearingloss if patients in immunomodulatory therapy have sensorineural hearing loss, the possibilityof syphilis should be considered.

참고문헌 (15)

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