Investigating the role of Sirtuins in cell reprogramming

키워드

참고문헌 (99)

1. Takahashi K, "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors", Cell, 126, pp.663~676 (2006)[DOI]
2. Rando TA, "Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock", Cell, 148, pp.46~57 (2012)[DOI]
3. Yu J, "Induced pluripotent stem cell lines derived from human somatic cells", Science, 318, pp.1917~1920 (2007)[DOI]
4. Blasco MA, "Genomic instability in iPS: time for a break", EMBO J, 30, pp.991~993 (2011)[DOI]
5. Suva ML, "Epigenetic reprogramming in cancer", Science, 339, pp.1567~1570 (2013)[DOI]
6. Ruiz S, "A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity", Curr Biol, 21, pp.45~52 (2011)[DOI]
7. Lopez-Otin C, "The hallmarks of aging", Cell, 153, pp.1194~1217 (2013)[DOI]
8. Marion RM, "Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells", Cell Stem Cell, 4, pp.141~154 (2009)[DOI]
9. Weissbein U, "Quality control: Genome maintenance in pluripotent stem cells", J Cell Biol, 204, pp.153~163 (2014)[DOI]
10. Folmes CD, "Somatic oxidative bioenergetics transitions into pluripotencydependent glycolysis to facilitate nuclear reprogramming", Cell Metab, 14, pp.264~271 (2011)[DOI]
11. Banito A, "Senescence impairs successful reprogramming to pluripotent stem cells", Genes Dev, 23, pp.2134~2139 (2009)[DOI]
12. Kimura H, "Visualizing posttranslational and epigenetic modifications of endogenous proteins in vivo", Histochem Cell Biol, 144, pp.101~109 (2015)[DOI]
13. Xiao Y, "Proteomics approaches in the identification of molecular signatures of mesenchymal stem cells", Adv Biochem Eng Biotechnol, 129, pp.153~176 (2013)
14. Mu WL, "Sox2 Deacetylation by Sirt1 Is Involved in Mouse Somatic Reprogramming", Stem Cells, 33, pp.2135~2147 (2015)[DOI]
15. Mostoslavsky R, "Genomic instability and aging-like phenotype in the absence of mammalian SIRT6", Cell, 124, pp.315~329 (2006)[DOI]
16. Laurent LC, "Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture", Cell Stem Cell, 8, pp.106~118 (2011)[DOI]
17. Taapken SM, "Karotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells", Nat Biotechnol, 29, pp.313~314 (2011)[DOI]
18. Araten DJ, "A quantitative measurement of the human somatic mutation rate", Cancer Res, 65, pp.8111~8117 (2005)[DOI]
19. Morin GB, "The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats", Cell, 59, pp.521~529 (1989)[DOI]
20. Vaziri H, "Spontaneous reversal of the developmental aging of normal human cells following transcriptional reprogramming", Regen Med, 5, pp.345~363 (2010)[DOI]
21. Marion RM, "Telomere rejuvenation during nuclear reprogramming", Curr Opin Genet Dev, 20, pp.190~196 (2010)[DOI]
22. Yehezkel S, "Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives", Epigenetics, 6, pp.63~75 (2011)[DOI]
23. Pasi CE, "Genomic instability in induced stem cells", Cell Death Differ, 18, pp.745~753 (2011)[DOI]
24. Lopez-Contreras AJ, "An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation", J Exp Med, 209, pp.455~461 (2012)[DOI]
25. Ruiz S, "Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells", Nat Commun, 6, pp.8036~ (2015)[DOI]
26. Mishra P, "Mitochondrial dynamics and inheritance during cell division, development and disease", Nat Rev Mol Cell Biol, 15, pp.634~646 (2014)[DOI]
27. Ji J, "Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells", Stem Cell Reports, 2, pp.44~51 (2014)[DOI]
28. Facucho-Oliveira JM, "Mitochondrial DNA replication during differentiation of murine embryonic stem cells", J Cell Sci, 120, pp.4025~4034 (2007)[DOI]
29. Moussaieff A, "Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells", Cell Metab, 21, pp.392~402 (2015)[DOI]
30. Prigione A, "The senescence-related mitochondrial", oxidative stress pathway is repressed in human induced pluripotent stem cells, 2010, pp.28, 721~733
31. Mandal S, "Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells", Stem Cells, 29, pp.486~495 (2011)[DOI]
32. Sathananthan H, "The fine structure of human embryonic stem cells", Reprod Biomed Online, 4, pp.56~61 (2002)[DOI]
33. Han H, "MBNL proteins repress ES-cell-specific alternative splicing and reprogramming", Nature, 498, pp.241~245 (2013)[DOI]
34. Wang L, "Drp1 is dispensable for mitochondria biogenesis in induction to pluripotency but required for differentiation of embryonic stem cells", Stem Cells Dev, 23, pp.2422~2434 (2014)[DOI]
35. Otera H, "Molecular mechanisms and physiologic functions of mitochondrial dynamics", J Biochem, 149, pp.241~251 (2011)[DOI]
36. Ramanathan A, "Direct control of mitochondrial function by mTOR", Proc Natl Acad Sci U S A, 106, pp.22229~22232 (2009)[DOI]
37. Wang S, "Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency", Cell Stem Cell, 13, pp.617~625 (2013)[DOI]
38. Greer EL, "An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans", Curr Biol, 17, pp.1646~1656 (2007)[DOI]
39. Wang Z, "Combinatorial patterns of histone acetylations and methylations in the human genome", Nat Genet, 40, pp.897~903 (2008)[DOI]
40. Lee S, "Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells", Cell Prolif, 42, pp.711~720 (2009)[DOI]
41. Michishita E, "SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin", Nature, 452, pp.492~496 (2008)[DOI]
42. Chen T, "Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells", Aging Cell, 10, pp.908~911 (2011)[DOI]
43. Huangfu D, "Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds", Nat Biotechnol, 26, pp.795~797 (2008)[DOI]
44. Vaquero A, "Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin", Mol Cell, 16, pp.93~105 (2004)[DOI]
45. Zhang ZN, "Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation", Stem Cells, 32, pp.157~165 (2014)[DOI]
46. Etchegaray JP, "The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine", Nat Cell Biol, 17, pp.545~557 (2015)[DOI]
47. Peng CH, "Delivery of Oct4 and SirT1 with cationic polyurethanes-short branch PEI to aged retinal pigment epithelium", Biomaterials, 32, pp.9077~9088 (2011)[DOI]
48. Liu PY, "The histone deacetylase SIRT2 stabilizes Myc oncoproteins", Cell Death Differ, 20, pp.503~514 (2013)[DOI]
49. Mao B, "Sirt1 deacetylates c-Myc and promotes c-Myc", Max association, 2011, pp.43, 1573~1581
50. Vaziri H, "hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase", Cell, 107, pp.149~159 (2001)[DOI]
51. Han MK, "SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization", Cell Stem Cell, 2, pp.241~251 (2008)[DOI]
52. Katada S, "Connecting threads: epigenetics and metabolism", Cell, 148, pp.24~28 (2012)[DOI]
53. Ryall JG, "The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells", Cell Stem Cell, 16, pp.171~183 (2015)[DOI]
54. Zwaans BM, "Interplay between sirtuins, MYC and hypoxia-inducible factor in cancerassociated metabolic reprogramming", Dis Model Mech, 7, pp.1023~1032 (2014)[DOI]
55. Tennen RI, "SIRT6 is required for maintenance of telomere position effect in human cells", Nat Commun, 2, pp.433~ (2011)[DOI]
56. Kugel S, "Chromatin and beyond: the multitasking roles for SIRT6", Trends Biochem Sci, 39, pp.72~81 (2014)[DOI]
57. Michishita E, "Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6", Cell Cycle, 8, pp.2664~2666 (2009)[DOI]
58. Toiber D, "SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling", Mol Cell, 51, pp.454~468 (2013)[DOI]
59. Galleano I, "A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation", J Med Chem, 59, pp.1021~1031 (2016)[DOI]
60. Baur JA, "Biochemical effects of SIRT1 activators", Biochim Biophys Acta, 1804, pp.1626~1634 (2010)[DOI]
61. Gu XS, "Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure", Genet Mol Res, 13, pp.323~335 (2014)[DOI]
62. Chaudhary N, "Metabolic benefits from Sirt1 and Sirt1 activators", Curr Opin Clin Nutr Metab Care, 12, pp.431~437 (2009)[DOI]
63. Bruckbauer A, "Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice", Nutr Metab (Lond), 9, pp.77~ (2012)[DOI]
64. Chauhan D, "Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells", Br J Haematol, 155, pp.588~598 (2011)[DOI]
65. Lahusen TJ, "SRT1720 induces lysosomal-dependent cell death of breast cancer cells", Mol Cancer Ther, 14, pp.183~192 (2015)
66. Maya JD, "Trypanosoma cruzi: inhibition of parasite growth and respiration by oxazolo(thiazolo)pyridine derivatives and its relationship to redox potential and lipophilicity", Exp Parasitol, 99, pp.1~6 (2001)[DOI]
67. thiazole derivatives as novel SIRT1 activators, "J Med Chem", 2009, 1275~1283, 10.1021[DOI]
68. Bonkowski MS, "Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds", Nat Rev Mol Cell Biol, 17, pp.679~690 (2016)[DOI]
69. Camins A, "Sirtuin activators: designing molecules to extend life span", Biochim Biophys Acta, 1799, pp.740~749 (2010)[DOI]
70. Botta G, "Current advances in the synthesis and antitumoral activity of SIRT1-2 inhibitors by modulation of p53 and pro-apoptotic proteins", Curr Med Chem, 19, pp.5871~5884 (2012)[DOI]
71. Villalba JM, "Sirtuin activators and inhibitors", Biofactors, 38, pp.349~359 (2012)[DOI]
72. Verdin E, "Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling", Trends Biochem Sci, 35, pp.669~675 (2010)[DOI]
73. Wang TT, "Pleiotropic effects of the sirtuin inhibitor sirtinol involves concentration-dependent modulation of multiple nuclear receptor-mediated pathways in androgen-responsive prostate cancer cell LNCaP", Mol Carcinog, 52, pp.676~685 (2013)[DOI]
74. Peck B, "SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2", Mol Cancer Ther, 9, pp.844~855 (2010)[DOI]
75. Naia L, "Sirtuins: double players in Huntington's disease", Biochim Biophys Acta, 1852, pp.2183~2194 (2015)[DOI]
76. Chen J, "SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling", J Biol Chem, 280, pp.40364~40374 (2005)[DOI]
77. Risitano R, "Flavonoid fraction of Bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-kappaB inhibition in THP-1 monocytes", PLoS One, 9, pp.e107431~ (2014)[DOI]
78. Polyakova O, "Identification of novel interacting partners of Sirtuin6", PLoS One, 7, pp.e51555~ (2012)[DOI]
79. Mopert K, "Loss of Drp1 function alters OPA1 processing and changes mitochondrial membrane organization", Exp Cell Res, 315, pp.2165~2180 (2009)[DOI]
80. Chen H, "Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development", J Cell Biol, 160, pp.189~200 (2003)[DOI]
81. Chen H, "Disruption of fusion results in mitochondrial heterogeneity and dysfunction", J Biol Chem, 280, pp.26185~26192 (2005)[DOI]
82. Christiansen EG, "Orientation of the mitochondria during mitosis", Nature, 163, pp.361~ (1949)
83. Cho DH, "Mitochondrial dynamics in cell death and neurodegeneration", Cell Mol Life Sci, 67, pp.3435~3447 (2010)[DOI]
84. Wilkerson DC, "Mitochondria: a sulfhydryl oxidase and fission GTPase connect mitochondrial dynamics with pluripotency in embryonic stem cells", Int J Biochem Cell Biol, 43, pp.1252~1256 (2011)[DOI]
85. Cipolat S, "OPA1 requires mitofusin 1 to promote mitochondrial fusion", Proc Natl Acad Sci U S A, 101, pp.15927~15932 (2004)[DOI]
86. Son MJ, "Mitofusins deficiency elicits mitochondrial metabolic reprogramming to pluripotency", Cell Death Differ, 22, pp.1957~1969 (2015)[DOI]
87. Tanno M, "Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1", J Biol Chem, 282, pp.6823~6832 (2007)[DOI]
88. Bell EL, "The SirT3 divining rod points to oxidative stress", Mol Cell, 42, pp.561~568 (2011)[DOI]
89. Giralt A, "Peroxisome proliferator-activated receptor-gamma coactivator-1alpha controls transcription of the Sirt3 gene, an essential component of the thermogenic brown adipocyte phenotype", J Biol Chem, 286, pp.16958~16966 (2011)[DOI]
90. Olichon A, "Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis", J Biol Chem, 278, pp.7743~7746 (2003)[DOI]
91. Park SH, "Sirt3, mitochondrial ROS, ageing, and carcinogenesis", Int J Mol Sci, 12, pp.6226~6239 (2011)[DOI]
92. Ou X, "SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress", Stem Cells, 32, pp.1183~1194 (2014)[DOI]
93. Yoshii SR, "Autophagy machinery in the context of mammalian mitophagy", Biochim Biophys Acta, 1853, pp.2797~2801 (2015)[DOI]
94. Eiyama A, "PINK1", Parkin-mediated mitophagy in mammalian cells, 2015, pp.33, 95~101
95. Koh H, "Silent information regulator 2 (Sir2) and Forkhead box O (FOXO) complement mitochondrial dysfunction and dopaminergic neuron loss in Drosophila PTEN-induced kinase 1 (PINK1) null mutant", J Biol Chem, 287, pp.12750~12758 (2012)[DOI]
96. Lim JH, "Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha", Mol Cell, 38, pp.864~878 (2010)[DOI]
97. Qiu X, "Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation", Cell Metab, 12, pp.662~667 (2010)[DOI]
98. Sundaresan NR, "Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice", J Clin Invest, 119, pp.2758~2771 (2009)
99. Morigi M, "Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury", J Clin Invest, 125, pp.715~726 (2015)[DOI]

관련 논문AI추천