Sirtuin signaling in cellular senescence and aging

키워드

참고문헌 (145)

1. North BJ, "Sirtuins : Sir2-related NAD-dependent protein deacetylases", Genome Biol, 5, pp.224~ (2004)
2. Toiber D, "Characterization of nuclear sirtuins : molecular mechanisms and physiological relevance", Handb Exp Pharmacol, 206, pp.189~224 (2011)
3. Guarente L, "Sir2 links chromatin silencing, metabolism, and aging", Genes Dev, 14, pp.1021~1026 (2000)
4. Kaeberlein M, "The SIR2", 3, Genes Dev, pp.1999, 13[DOI]
5. Imai S, "Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase", Nature, 403, pp.795~800 (2000)
6. Landry J, "The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases", Proc Natl Acad Sci U S A, 97, pp.5807~5811 (2000)
7. Grabowska W, "Sirtuins, a promising target in slowing down the ageing process", Biogerontology, 18, pp.447~476 (2017)
8. Bamps S, "The Caenorhabditis elegans sirtuin gene, sir-2. 1, is widely expressed and induced upon caloric restriction", Mech Ageing Dev, 130, pp.762~770 (2009)
9. Newman BL, "A Drosophila homologue of Sir2 modifies position-effect variegation but does not affect life span", Genetics, 162, pp.1675~1685 (2002)
10. Rogina B, "Sir2 mediates longevity in the fly through a pathway related to calorie restriction", Proc Natl Acad Sci U S A, 101, pp.15998~16003 (2004)
11. Wood JG, "Sirt4 is a mitochondrial regulator of metabolism and lifespan in Drosophila melanogaster", Proc Natl Acad Sci U S A, 115, pp.1564~1569 (2018)
12. Frye RA, "Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins", Biochem Biophys Res Commun, 273, pp.793~798 (2000)
13. Michishita E, "Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins", Mol Biol Cell, 16, pp.4623~4635 (2005)
14. Scher MB, "SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress", Genes Dev, 21, pp.920~928 (2007)
15. Du J, "Sirt5 is a NADdependent protein lysine demalonylase and desuccinylase", Science, 334, pp.806~809 (2011)
16. Cristofalo VJ, "Replicative senescence : a critical review", Mech Ageing Dev, 125, pp.827~848 (2004)
17. Munoz-Espin D, "Cellular senescence : from physiology to pathology", Nat Rev Mol Cell Biol, 15, pp.482~496 (2014)
18. Krtolica A, "Cancer and aging : a model for the cancer promoting effects of the aging stroma", Int J Biochem Cell Biol, 34, pp.1401~1414 (2002)
19. Sasaki T, "Progressive loss of SIRT1 with cell cycle withdrawal", Aging Cell, 5, pp.413~422 (2006)
20. Anwar T, "Increased expression of SIRT2 is a novel marker of cellular senescence and is dependent on wild type p53 status", Cell Cycle, 15, pp.1883~1897 (2016)
21. Son MJ, "Restoration of Mitochondrial NAD(+)Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells", Stem Cells, 34, pp.2840~2851 (2016)
22. Chen J, "Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration", Cell Death Dis, 9, pp.56~ (2018)
23. Ota H, "Sirt1 modulates premature senescence-like phenotype in human endothelial cells", J Mol Cell Cardiol, 43, pp.571~579 (2007)
24. Menghini R, "MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1", Circulation, 120, pp.1524~1532 (2009)
25. Mostoslavsky R, "Genomic instability and aging-like phenotype in the absence of mammalian SIRT6", Cell, 124, pp.315~329 (2006)
26. Kim MY, "The PPARdelta-mediated inhibition of angiotensin II-induced premature senescence in human endothelial cells is SIRT1-dependent", Biochem Pharmacol, 84, pp.1627~1634 (2012)
27. Yao H, "SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice", J Clin Invest, 122, pp.2032~2045 (2012)
28. Zu Y, "SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells", Circ Res, 106, pp.1384~1393 (2010)
29. Michan S, "Sirtuins in mammals : insights into their biological function", Biochem J, 404, pp.1~13 (2007)
30. Rosenberg MI, "Drosophila Sir2is required for heterochromatic silencing and by euchromatic Hairy", E(Spl)bHLH repressors in segmentation and sex determination, 2002, pp.109, 447~458
31. Astrom SU, "The Drosophila melanogaster sir2+ gene is nonessential and has only minor effects on position-effect variegation", Genetics, 163, pp.931~937 (2003)
32. Yamashita S, "SIRT1 prevents replicative senescence of normal human umbilical cord fibroblast through potentiating the transcription of human telomerase reverse transcriptase gene", Biochem Biophys Res Commun, 417, pp.630~634 (2012)
33. Watroba M, "Sirtuins, epigenetics and longevity", Ageing Res Rev, 40, pp.11~19 (2017)
34. 정재민, "SIRT1 promotes DNA repair activity and deacetylation of Ku70", Experimental and Molecular Medicine, 39(1), pp.8~13 (2007), 생화학분자생물학회
35. Yuan Z, "A functional link between SIRT1 deacetylase and NBS1 in DNA damage response", Cell Cycle, 6, pp.2869~2871 (2007)
36. Oberdoerffer P, "SIRT1redistribution on chromatin promotes genomic stability but alters gene expression during aging", Cell, 135, pp.907~918 (2008)
37. Michishita E, "SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin", Nature, 452, pp.492~496 (2008)
38. Jeong SM, "SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism", Cancer Cell, 23, pp.450~463 (2013)
39. Brunet A, "Stressdependent regulation of FOXO transcription factors by the SIRT1 deacetylase", Science, 303, pp.2011~2015 (2004)
40. Giannakou ME, "The interaction between FOXO and SIRT1 : tipping the balance towards survival", Trends Cell Biol, 14, pp.408~412 (2004)
41. Luo J, "Negative control of p53 by Sir2alpha promotes cell survival under stress", Cell, 107, pp.137~148 (2001)
42. Langley E, "Human SIR2 deacetylates p53 and antagonizes PML", p53-induced cellular senescence, 2002, pp.21, 2383~2396
43. Kawahara TL, "SIRT6links histone H3 lysine 9 deacetylation to NF-kappaBdependent gene expression and organismal life span", Cell, 136, pp.62~74 (2009)
44. Xu Z, "The miR-29b-Sirt1 axis regulates self-renewal of mouse embryonic stem cells in response to reactive oxygen species", Cell Signal, 26, pp.1500~1505 (2014)
45. Saunders LR, "miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues", Aging (Albany NY), 2, pp.415~431 (2010)
46. Rimmele P, "Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells", Stem Cell Reports, 3, pp.44~59 (2014)
47. Chen J, "Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence", Am J Pathol, 180, pp.973~983 (2012)
48. Yuan HF, "SIRT1 is required for long-term growth of human mesenchymal stem cells", J Mol Med (Berl), 90, pp.389~400 (2012)
49. Denu RA, "SIRT3 Enhances Mesenchymal Stem Cell Longevity and Differentiation", Oxid Med Cell Longev, 2017, pp.5841716~ (2017)
50. Tissenbaum HA, "Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans", Nature, 410, pp.227~230 (2001)
51. Kanfi Y, "The sirtuin SIRT6regulates lifespan in male mice", Nature, 483, pp.218~221 (2012)
52. Watroba M, "The role of sirtuins in aging and age-related diseases", Adv Med Sci, 61, pp.52~62 (2016)
53. Viswanathan M, "A role for SIR-2. 1 regulation of ER stress response genes in determining C. elegans life span", Dev Cell, 9, pp.605~615 (2005)
54. Howitz KT, "Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan", Nature, 425, pp.191~196 (2003)
55. Wang Y, "Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16", FOXO, 2006, pp.127, 48~56
56. Banerjee KK, "dSir2 in the adult fat body, but not in muscles, regulates life span in a diet-dependent manner", Cell Rep, 2, pp.1485~1491 (2012)
57. Satoh A, "Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH", Cell Metab, 18, pp.416~430 (2013)
58. Vakhrusheva O, "Sirt7increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice", Circ Res, 102, pp.703~710 (2008)
59. Rose G, "Variability of the SIRT3 gene, human silent information regulator Sir2homologue, and survivorship in the elderly", Exp Gerontol, 38, pp.1065~1070 (2003)
60. Berdichevsky A, "C. elegans SIR-2. 1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span", Cell, 125, pp.1165~1177 (2006)
61. Heidler T, "Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2. 1", Biogerontology, 11, pp.183~195 (2010)
62. Banerjee KK, "dSir2 deficiency in the fatbody, but not muscles, affects systemic insulin signaling, fat mobilization and starvation survival in flies", Aging (Albany NY), 4, pp.206~223 (2012)
63. Liang F, "SIRT1 and insulin resistance", Nat Rev Endocrinol, 5, pp.367~373 (2009)
64. Zhang J, "The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation", J Biol Chem, 282, pp.34356~34364 (2007)
65. Curtis R, "Aging networks in Caenorhabditis elegans : AMP-activated protein kinase(aak-2)links multiple aging and metabolism pathways", Aging Cell, 5, pp.119~126 (2006)
66. Price NL, "SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function", Cell Metab, 15, pp.675~690 (2012)
67. Wang Y, "C. elegans 14-3-3 proteins regulate life span and interact with SIR-2. 1 and DAF-16", FOXO, 2006, pp.127, 741~747
68. Berdichevsky A, "3-Ketoacyl thiolase delays aging of Caenorhabditis elegans and is required for lifespan extension mediated by sir-2. 1", Proc Natl Acad Sci U S A, 107, pp.18927~18932 (2010)
69. Rizki G, "The evolutionarily conserved longevity determinants HCF-1 and SIR-2. 1", SIRT1collaborate to regulate DAF-16, PLoS Genet, pp.2011, 7[DOI]
70. Mouchiroud L, "The NAD(+)", Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling, 2013, pp.154, 430~441
71. Dang W, "The controversial world of sirtuins", Drug Discov Today Technol, 12, pp.e9~e17 (2012)[DOI]
72. Naiman S, "The contentious history of sirtuin debates", Rambam Maimonides Med J, 3, pp.e0022~ (2012)
73. Burnett C, "Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila", Nature, 477, pp.482~485 (2011)
74. Viswanathan M, "Regulation of Caenorhabditis elegans lifespan by sir-2. 1 transgenes", Nature, 477, pp.E1~E2 (2011)
75. Whitaker R, "Increased expression of Drosophila Sir2 extends life span in a dose-dependent manner", Aging (Albany NY), 5, pp.682~691 (2013)
76. Bauer JH, "dSir2 and Dmp53 interact to mediate aspects of CR-dependent lifespan extension in D. melanogaster", Aging (Albany NY), 1, pp.38~48 (2009)
77. Alcendor RR, "Sirt1 regulates aging and resistance to oxidative stress in the heart", Circ Res, 100, pp.1512~1521 (2007)
78. 이신해, "Caloric restriction and its mimetics", BMB Reports, 46(4), pp.181~187 (2013), 생화학분자생물학회
79. Canto C, "Caloric restriction, SIRT1and longevity", Trends Endocrinol Metab, 20, pp.325~331 (2009)
80. Sinclair DA, "Toward a unified theory of caloric restriction and longevity regulation", Mech Ageing Dev, 126, pp.987~1002 (2005)
81. Cohen HY, "Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase", Science, 305, pp.390~392 (2004)
82. Rogina B, "Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction", Science, 298, pp.1745~ (2002)
83. Chen D, "Tissue-specific regulation of SIRT1 by calorie restriction", Genes Dev, 22, pp.1753~1757 (2008)
84. Firestein R, "The SIRT1deacetylase suppresses intestinal tumorigenesis and colon cancer growth", PLoS One, 3, pp.e2020~ (2008)
85. Kim HS, "Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis", Cell Metab, 12, pp.224~236 (2010)
86. Palacios OM, "Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle", Aging (Albany NY), 1, pp.771~783 (2009)
87. Someya S, "Sirt3mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction", Cell, 143, pp.802~812 (2010)
88. Lin SJ, "Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae", Science, 289, pp.2126~2128 (2000)
89. Anderson RM, "Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae", Nature, 423, pp.181~185 (2003)
90. Hansen M, "Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans", Aging Cell, 6, pp.95~110 (2007)
91. Boily G, "SirT1regulates energy metabolism and response to caloric restriction in mice", PLoS One, 3, pp.e1759~ (2008)
92. Qiu X, "Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation", Cell Metab, 12, pp.662~667 (2010)
93. Kaeberlein M, "Sir2-independent life span extension by calorie restriction in yeast", PLoS Biol, 2, pp.E296~ (2004)
94. Smith DL Jr, "Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins", Aging Cell, 6, pp.649~662 (2007)
95. Fabrizio P, "Sir2blocks extreme life-span extension", Cell, 123, pp.655~667 (2005)
96. Tsuchiya M, "Sirtuinindependent effects of nicotinamide on lifespan extension from calorie restriction in yeast", Aging Cell, 5, pp.505~514 (2006)
97. Kaeberlein TL, "Lifespan extension in Caenorhabditis elegans by complete removal of food", Aging Cell, 5, pp.487~494 (2006)
98. Lee GD, "Dietary deprivation extends lifespan in Caenorhabditis elegans", Aging Cell, 5, pp.515~524 (2006)
99. Greer EL, "Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans", Aging Cell, 8, pp.113~127 (2009)
100. Guarente L, "Calorie restriction and SIR2 genes--towards a mechanism", Mech Ageing Dev, 126, pp.923~928 (2005)
101. Lamming DW, "HST2 mediates SIR2-independent life-span extension by calorie restriction", Science, 309, pp.1861~1864 (2005)
102. Wood JG, "Sirtuin activators mimic caloric restriction and delay ageing in metazoans", Nature, 430, pp.686~689 (2004)
103. Hubbard BP, "Evidence for a common mechanism of SIRT1 regulation by allosteric activators", Science, 339, pp.1216~1219 (2012)
104. Valenzano DR, "Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate", Curr Biol, 16, pp.296~300 (2006)
105. Rascon B, "The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction", Aging (Albany NY), 4, pp.499~508 (2012)
106. Ota H, "Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells", Arterioscler Thromb Vasc Biol, 28, pp.1634~1639 (2008)
107. Jamal J, "Paeonol protects against premature senescence in endothelial cells by modulating Sirtuin 1 pathway", J Ethnopharmacol, 154, pp.428~436 (2014)
108. Ota H, "Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway", Arterioscler Thromb Vasc Biol, 30, pp.2205~2211 (2010)
109. Suo R, "Hydrogen sulfide prevents H(2)O(2)-induced senescence in human umbilical vein endothelial cells through SIRT1activation", Mol Med Rep, 7, pp.1865~1870 (2013)
110. Lee MK, "Antihepatotoxic activity of icariin, a major constituent of Epimedium koreanum", Planta Med, 61, pp.523~526 (1995)
111. Lee YA, "Protective effect of persimmon(Diospyros kaki)peel proanthocyanidin against oxidative damage under H2O2-induced cellular senescence", Biol Pharm Bull, 31, pp.1265~1269 (2008)
112. Ramis MR, "Caloric restriction, resveratrol and melatonin:Role of SIRT1 and implications for aging and related-diseases", Mech Ageing Dev, 146-148, pp.28~41 (2015)
113. Sun Q, "Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-beta25-35 in rat cortical neurons", Biochem Biophys Res Commun, 448, pp.89~94 (2014)
114. Kayashima Y, "Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster", Sci Rep, 7, pp.43679~ (2017)
115. Lee KS, "Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster", Rejuvenation Res, 13, pp.561~570 (2010)
116. Bonkowski MS, "Slowing ageing by design : the rise of NAD(+)and sirtuin-activating compounds", Nat Rev Mol Cell Biol, 17, pp.679~690 (2016)
117. Hubbard BP, "Small molecule SIRT1 activators for the treatment of aging and age-related diseases", Trends Pharmacol Sci, 35, pp.146~154 (2014)
118. Milne JC, "Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes", Nature, 450, pp.712~716 (2007)
119. Minor RK, "SRT1720improves survival and healthspan of obese mice", Sci Rep, 1, pp.70~ (2011)
120. Mercken EM, "SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass", Aging Cell, 13, pp.787~796 (2014)
121. pyridines and related heterocyclic analogs as novel SIRT1 activators, "Bioorg Med Chem Lett", 2009, 2350~2353
122. thiazole derivatives as novel SIRT1 activators, "J Med Chem", 2009, 1275~1283
123. Mai A, "Study of 1, 4-dihydropyridine structural scaffold : discovery of novel sirtuin activators and inhibitors", J Med Chem, 52, pp.5496~5504 (2009)
124. Sauve AA, "Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition", Mol Cell, 17, pp.595~601 (2005)
125. Pacholec M, "SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1", J Biol Chem, 285, pp.8340~8351 (2010)
126. Borra MT, "Mechanism of human SIRT1 activation by resveratrol", J Biol Chem, 280, pp.17187~17195 (2005)
127. Kaeberlein M, "Substrate-specific activation of sirtuins by resveratrol", J Biol Chem, 280, pp.17038~17045 (2005)
128. Chung JH, "Using PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol", Aging (Albany NY), 4, pp.144~145 (2012)
129. Bass TM, "Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans", Mech Ageing Dev, 128, pp.546~552 (2007)
130. Hashimoto T, "Nicotinamide adenine dinucleotide extends the lifespan of Caenorhabditis elegans mediated by sir-2. 1and daf-16", Biogerontology, 11, pp.31~43 (2010)
131. Scheibye-Knudsen M, "A high-fat diet and NAD(+)activate Sirt1 to rescue premature aging in cockayne syndrome", Cell Metab, 20, pp.840~855 (2014)
132. Zhang H, "NAD(+)repletion improves mitochondrial and stem cell function and enhances life span in mice", Science, 352, pp.1436~1443 (2016)
133. Yoshino J, "Nicotinamide mononucleotide, a key NAD(+)intermediate, treats the pathophysiology of diet-and age-induced diabetes in mice", Cell Metab, 14, pp.528~536 (2011)
134. Canto C, "The NAD(+)precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity", Cell Metab, 15, pp.838~847 (2012)
135. Schmeisser K, "Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide", Nat Chem Biol, 9, pp.693~700 (2013)
136. Rongvaux A, "Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis", Eur J Immunol, 32, pp.3225~3234 (2002)
137. Revollo JR, "The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells", J Biol Chem, 279, pp.50754~50763 (2004)
138. Balan V, "Life span extension and neuronal cell protection by Drosophila nicotinamidase", J Biol Chem, 283, pp.27810~27819 (2008)
139. Gomes AP, "Declining NAD(+)induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging", Cell, 155, pp.1624~1638 (2013)
140. Barbosa MT, "The enzyme CD38(a NAD glycohydrolase, EC 3. 2. 2. 5)is necessary for the development of diet-induced obesity", FASEB J, 21, pp.3629~3639 (2007)
141. Canto C, "Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle", Cell Metab, 11, pp.213~219 (2010)
142. Fulco M, "Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt", Dev Cell, 14, pp.661~673 (2008)
143. Canto C, "AMPK regulates energy expenditure by modulating NAD+metabolism and SIRT1 activity", Nature, 458, pp.1056~1060 (2009)
144. Moroz N, "Dietary restriction involves NAD(+)-dependent mechanisms and a shift toward oxidative metabolism", Aging Cell, 13, pp.1075~1085 (2014)
145. Lin SJ, "Calorie restriction extends yeast life span by lowering the level of NADH", Genes Dev, 18, pp.12~16 (2004)

관련 논문AI추천