The role of NUMB/NUMB isoforms in cancer stem cells

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참고문헌 (80)

1. Yoo YD, "Molecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cells", J Anal Sci Technol, 6, pp.28~ (2015)
2. Budillon A, "Identification and targeting of stem cell-activated pathways in cancer therapy", Stem Cells Int, 2019, pp.8549020~ (2019)
3. Yang L, "Targeting cancer stem cell pathways for cancer therapy", Signal Transduct Target Ther, 5, pp.8~ (2020)
4. Clevers H, "Stem cells, asymmetric division and cancer", Nat Genet, 37, pp.1027~1028 (2005)
5. Knoblich JA, "Mechanisms of asymmetric stem cell division", Cell, 132, pp.583~597 (2008)
6. Knoblich JA, "Asymmetric cell division : recent developments and their implications for tumour biology", Nat Rev Mol Cell Biol, 11, pp.849~860 (2010)
7. Majumdar S, "Cell division symmetry control and cancer stem cells", AIMS Mol Sci, 7, pp.82~98 (2020)
8. Badve S, "Breast-cancer stem cells-beyond semantics", Lancet Oncol, 13, pp.e43~e48 (2012)
9. Najafi M, "Cancer stem cell(a)symmetry & plasticity : tumorigenesis and therapy relevance", Life Sci, 231, pp.116520~ (2019)
10. Brooks MD, "Therapeutic implications of cellular heterogeneity and plasticity in breast cancer", Cell Stem Cell, 17, pp.260~271 (2015)
11. Plaks V, "The cancer stem cell niche : how essential is the niche in regulating stemness of tumor cells?", Cell Stem Cell, 16, pp.225~238 (2015)
12. Morrison SJ, "Asymmetric and symmetric stem-cell divisions in development and cancer", Nature, 441, pp.1068~1074 (2006)
13. Losick VP, "Drosophila stem cell niches : a decade of discovery suggests a unified view of stem cell regulation", Dev Cell, 21, pp.159~171 (2011)
14. Santoro A, "Molecular mechanisms of asymmetric divisions in mammary stem cells", EMBO Rep, 17, pp.1700~1720 (2016)
15. Venkei ZG, "Emerging mechanisms of asymmetric stem cell division", J Cell Biol, 217, pp.3785~3795 (2018)
16. Knoblich JA, "Asymmetric cell division during animal development", Nat Rev Mol Cell Biol, 2, pp.11~20 (2001)
17. Gehring WJ, "Precis of Edwin G. Conklin’s JEZ article, "Mosaic Development in Ascidian Eggs", J Exp Zool A Comp Exp Biol, 301, pp.461~463 (2004)
18. Sunchu B, "Principles and mechanisms of asymmetric cell division", Development, 147, pp.dev167650~ (2020)
19. Uemura T, "Numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos", Cell, 58, pp.349~360 (1989)
20. Cayouette M, "Asymmetric segregation of Numb : a mechanism for neural specification from Drosophila to mammals", Nat Neurosci, 5, pp.1265~1269 (2002)
21. Dho SE, "The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domaincontaining numb binding protein, LNX", J Biol Chem, 273, pp.9179~9187 (1998)
22. Gulino A, "The multiple functions of Numb", Exp Cell Res, 316, pp.900~906 (2010)
23. Zhong W, "Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis", Neuron, 17, pp.43~53 (1996)
24. Bani-Yaghoub M, "A switch in numb isoforms is a critical step in cortical development", Dev Dyn, 236, pp.696~705 (2007)
25. Dho SE, "Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain", J Biol Chem, 274, pp.33097~33104 (1999)
26. Karaczyn A, "Two novel human NUMB isoforms provide a potential link between development and cancer", Neural Dev, 5, pp.31~ (2010)
27. Karaczyn AA, "Human NUMB6 induces epithelial-mesenchymal transition and enhances breast cancer cells migration and invasion", J Cell Biochem, 118, pp.237~251 (2017)
28. Li Y, "A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells", EMBO Rep, 22, pp.e50535~ (2021)
29. Wei R, "NUMB regulates the endocytosis and activity of the anaplastic lymphoma kinase in an isoform-specific manner", J Mol Cell Biol, 11, pp.994~1005 (2019)
30. Kavanaugh WM, "PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine", Science, 268, pp.1177~1179 (1995)
31. Verdi JM, "Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate", Curr Biol, 6, pp.1134~1145 (1996)
32. Salcini AE, "Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module", Genes Dev, 11, pp.2239~2249 (1997)
33. Santolini E, "Numb is an endocytic protein", J Cell Biol, 151, pp.1345~1352 (2000)
34. Verdi JM, "Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage", Proc Natl Acad Sci U S A, 96, pp.10472~10476 (1999)
35. Revil T, "Alternative splicing is frequent during early embryonic development in mouse", BMC Genomics, 11, pp.399~ (2010)
36. Dooley CM, "Involvement of numb in vertebrate retinal development : evidence for multiple roles of numb in neural differentiation and maturation", J Neurobiol, 54, pp.313~325 (2003)
37. Nilsen TW, "Expansion of the eukaryotic proteome by alternative splicing", Nature, 463, pp.457~463 (2010)
38. Climente-Gonzalez H, "The functional impact of alternative splicing in cancer", Cell Rep, 20, pp.2215~2226 (2017)
39. Kahles A, "Comprehensive analysis of alternative splicing across tumors from 8, 705 patients", Cancer Cell, 34, pp.211~224 (2018)
40. Sciarrillo R, "The role of alternative splicing in cancer : from oncogenesis to drug resistance", Drug Resist Updat, 53, pp.100728~ (2020)
41. Lu Y, "Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma", Hepatology, 62, pp.1122~1131 (2015)
42. Misquitta-Ali CM, "Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer", Mol Cell Biol, 31, pp.138~150 (2011)
43. Zhao YJ, "Alternative splicing of VEGFA, APP and NUMB genes in colorectal cancer", World J Gastroenterol, 21, pp.6550~6560 (2015)
44. Kim KK, "Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development", J Cell Biol, 200, pp.443~458 (2013)
45. Tarn WY, "RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression", Mol Biol Cell, 27, pp.1676~1683 (2016)
46. Kyriazis GA, "Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner : implications for Alzheimer disease pathogenesis", J Biol Chem, 283, pp.25492~25502 (2008)
47. Ntelios D, "Numb and Alzheimer’s disease : the current picture", Front Neurosci, 6, pp.145~ (2012)
48. Dho SE, "Dynamic regulation of mammalian numb by G proteincoupled receptors and protein kinase C activation : structural determinants of numb association with the cortical membrane", Mol Biol Cell, 17, pp.4142~4155 (2006)
49. Sato K, "Numb controls E-cadherin endocytosis through p120 catenin with aPKC", Mol Biol Cell, 22, pp.3103~3119 (2011)
50. Pece S, "NUMB-ing down cancer by more than just a NOTCH", Biochim Biophys Acta, 1815, pp.26~43 (2011)
51. Colaluca IN, "NUMB controls p53 tumour suppressor activity", Nature, 451, pp.76~80 (2008)
52. Westhoff B, "Alterations of the Notch pathway in lung cancer", Proc Natl Acad Sci U S A, 106, pp.22293~22298 (2009)
53. Hong J, "The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma", Oncotarget, 5, pp.5602~5614 (2014)
54. Pece S, "Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis", J Cell Biol, 167, pp.215~221 (2004)
55. Siddique HR, "NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer", Hepatology, 62, pp.1466~1479 (2015)
56. Tosoni D, "The Numb", p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells, 2015, pp.211, 845~862
57. Rajendran D, "Regulation of Numb isoform expression by activated ERK signaling", Oncogene, 35, pp.5202~5213 (2016)
58. Langer W, "Exon array analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer", BMC Genomics, 11, pp.676~ (2010)
59. Artavanis-Tsakonas S, "Notch signaling : cell fate control and signal integration in development", Science, 284, pp.770~776 (1999)
60. Hori K, "Notch signaling at a glance", J Cell Sci, 126, pp.2135~2140 (2013)
61. Guo M, "Control of daughter cell fates during asymmetric division : interaction of Numb and Notch", Neuron, 17, pp.27~41 (1996)
62. Schweisguth F, "Regulation of notch signaling activity", Curr Biol, 14, pp.R129~R138 (2004)
63. Wai P, "Cell division genes promote asymmetric interaction between Numb and Notch in the Drosophila CNS", Development, 126, pp.2759~2770 (1999)
64. Shao X, "Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4", J Biol Chem, 292, pp.20628~20643 (2017)
65. Brou C, "Intracellular trafficking of Notch receptors and ligands", Exp Cell Res, 315, pp.1549~1555 (2009)
66. Frise E, "The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage", Proc Natl Acad Sci U S A, 93, pp.11925~11932 (1996)
67. Flores AN, "NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer", Nat Rev Urol, 11, pp.499~507 (2014)
68. Crawford TQ, "The notch response inhibitor DAPT enhances neuronal differentiation in embryonic stem cell-derived embryoid bodies independently of sonic hedgehog signaling", Dev Dyn, 236, pp.886~892 (2007)
69. Liu X, "DAPT suppresses the proliferation of human glioma cell line SHG-44", Asian Pac J Trop Med, 7, pp.552~556 (2014)
70. Luo Z, "NUMB enhances Notch signaling by repressing ubiquitination of NOTCH1intracellular domain", J Mol Cell Biol, 12, pp.345~358 (2020)
71. Bolos V, "Notch signaling in development and cancer", Endocr Rev, 28, pp.339~363 (2007)
72. Leong KG, "Recent insights into the role of Notch signaling in tumorigenesis", Blood, 107, pp.2223~2233 (2006)
73. Nowell CS, "Notch as a tumour suppressor", Nat Rev Cancer, 17, pp.145~159 (2017)
74. Kruse JP, "Modes of p53 regulation", Cell, 137, pp.609~622 (2009)
75. Bieging KT, "Unravelling mechanisms of p53-mediated tumour suppression", Nat Rev Cancer, 14, pp.359~370 (2014)
76. Nag S, "The MDM2-p53 pathway revisited", J Biomed Res, 27, pp.254~271 (2013)
77. Wang Z, "Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling", EMBO J, 28, pp.2360~2373 (2009)
78. Steed E, "Dynamics and functions of tight junctions", Trends Cell Biol, 20, pp.142~149 (2010)
79. Wang Z, "The role of Notch signaling pathway in epithelial-mesenchymal transition(EMT)during development and tumor aggressiveness", Curr Drug Targets, 11, pp.745~751 (2010)
80. Qi S, "Aberrant expression of Notch1", numb, Reprod Biol Endocrinol, pp.2015, 13[DOI]

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