Regulation of the Hippo signaling pathway by ubiquitin modification

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참고문헌 (73)

1. Meng Z, "Mechanisms of Hippo pathway regulation", Genes Dev, 30, pp.1~17 (2016)[DOI]
2. Zanconato F, "YAP", TAZ at the Roots of Cancer, 2016, pp.29, 783~803
3. Hershko A, "The ubiquitin system", Annu Rev Biochem, 67, pp.425~479 (1998)[DOI]
4. Koegl M, "A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly", Cell, 96, pp.635~644 (1999)[DOI]
5. Ikeda F, "Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series", EMBO Rep, 9, pp.536~542 (2008)[DOI]
6. Kirisako T, "A ubiquitin ligase complex assembles linear polyubiquitin chains", EMBO J, 25, pp.4877~4887 (2006)[DOI]
7. Li W, "Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling", PLoS One, 3, pp.e1487~ (2008)[DOI]
8. Nijman SM, "A genomic and functional inventory of deubiquitinating enzymes", Cell, 123, pp.773~786 (2005)[DOI]
9. Canning M, "A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7", J Biol Chem, 279, pp.38160~38168 (2004)[DOI]
10. Wu X, "Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8", Mol Cell Biol, 24, pp.7748~7757 (2004)[DOI]
11. Hetfeld BK, "The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1", Curr Biol, 15, pp.1217~1221 (2005)[DOI]
12. Brooks CL, "The p53--Mdm2--HAUSP complex is involved in p53 stabilization by HAUSP", Oncogene, 26, pp.7262~7266 (2007)[DOI]
13. Trompouki E, "CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members", Nature, 424, pp.793~796 (2003)[DOI]
14. Wertz IE, "De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling", Nature, 430, pp.694~699 (2004)[DOI]
15. Liu CY, "The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase", J Biol Chem, 285, pp.37159~37169 (2010)[DOI]
16. Zhao B, "A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)", Genes Dev, 24, pp.72~85 (2010)[DOI]
17. Huang W, "The N-terminal phosphodegron targets TAZ", WWTR1 protein for SCFbeta-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition, 2012, pp.287, 26245~26253
18. Tu K, "Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma", Mol Cancer, 13, pp.110~ (2014)[DOI]
19. Wang W, "PTPN14 is required for the density-dependent control of YAP1", Genes Dev, 26, pp.1959~1971 (2012)[DOI]
20. Chan SW, "Hippo pathway-independent restriction of TAZ and YAP by angiomotin", J Biol Chem, 286, pp.7018~7026 (2011)[DOI]
21. Wang W, "Angiomotin-like proteins associate with and negatively regulate YAP1", J Biol Chem, 286, pp.4364~4370 (2011)[DOI]
22. Zhao B, "Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein", Genes Dev, 25, pp.51~63 (2011)[DOI]
23. Wang C, "The Nedd4-like ubiquitin E3 ligases target angiomotin", p130 to ubiquitindependent degradation, 2015, pp.444, 279~289
24. Wang W, "Tankyrase Inhibitors Target YAP by Stabilizing Angiomotin Family Proteins", Cell Rep, 13, pp.524~532 (2015)[DOI]
25. Zhang Y, "RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling", Nat Cell Biol, 13, pp.623~629 (2011)[DOI]
26. Thanh Nguyen H, "Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover", Cell Discov, 2, pp.16001~ (2016)
27. Huang J, "The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP", Cell, 122, pp.421~434 (2005)[DOI]
28. Lei QY, "TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway", Mol Cell Biol, 28, pp.2426~2436 (2008)[DOI]
29. Hamaratoglu F, "The tumour-suppressor genes NF2", Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis, 2006, pp.8, 27~36
30. Genevet A, "Kibra is a regulator of the Salvador", Warts, Dev Cell, pp.2010, 18[DOI]
31. Yu J, "Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded", Dev Cell, 18, pp.288~299 (2010)[DOI]
32. Visser-Grieve S, "LATS1 tumor suppressor is a novel actin-binding protein and negative regulator of actin polymerization", Cell Res, 21, pp.1513~1516 (2011)[DOI]
33. Mo JS, "Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)", Genes Dev, 26, pp.2138~2143 (2012)[DOI]
34. Yu FX, "Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling", Cell, 150, pp.780~791 (2012)[DOI]
35. Zhao B, "Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis", Genes Dev, 26, pp.54~68 (2012)[DOI]
36. Wada K, "Hippo pathway regulation by cell morphology and stress fibers", Development, 138, pp.3907~3914 (2011)[DOI]
37. Chen HI, "The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules", Proc Natl Acad Sci U S A, 92, pp.7819~7823 (1995)[DOI]
38. "Proc Natl Acad Sci U S A", 2011, 4870~4875, 10.1073[DOI]
39. Salah Z, "Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity", Cancer Res, 71, pp.2010~2020 (2011)[DOI]
40. Salah Z, "NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation", Cell Cycle, 12, pp.3817~3823 (2013)[DOI]
41. Bae SJ, "NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo signalling pathway", Nat Commun, 6, pp.6314~ (2015)[DOI]
42. Yeung B, "WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells", PLoS One, 8, pp.e61027~ (2013)[DOI]
43. Cao L, "Ubiquitin E3 ligase dSmurf is essential for Wts protein turnover and Hippo signaling", Biochem Biophys Res Commun, 454, pp.167~171 (2014)[DOI]
44. Li W, "Merlin", NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus, 2010, pp.140, 477~490
45. Li W, "Merlin", NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus, 2014, pp.26, 48~60
46. Deng J, "Cullin 4A (CUL4A), a direct target of miR-9 and miR-137, promotes gastric cancer proliferation and invasion by regulating the Hippo signaling pathway", Oncotarget, 7, pp.10037~10050 (2016)
47. Sang Y, "The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications", Oncotarget, 6, pp.42590~42602 (2015)
48. Ma B, "Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase", Nat Cell Biol, 17, pp.95~103 (2015)
49. Kim M, "Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition", EMBO Rep, 17, pp.64~78 (2016)[DOI]
50. Kim Y, "Deubiquitinase YOD1 potentiates YAP", TAZ activities through enhancing ITCH stability, 2017, pp.114, 4691~4696
51. Praskova M, "MOBKL1A", MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation, 2008, pp.18, 311~321
52. Wei X, "Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila", EMBO J, 26, pp.1772~1781 (2007)[DOI]
53. Chan EH, "The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1", Oncogene, 24, pp.2076~2086 (2005)[DOI]
54. Lignitto L, "Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth", Nat Commun, 4, pp.1822~ (2013)[DOI]
55. Tapon N, "salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines", Cell, 110, pp.467~478 (2002)[DOI]
56. Callus BA, "Vaux, Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation", FEBS J, 273, pp.4264~4276 (2006)[DOI]
57. Lee JH, "A crucial role of WW45 in developing epithelial tissues in the mouse", EMBO J, 27, pp.1231~1242 (2008)[DOI]
58. Lu L, "Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver", Proc Natl Acad Sci U S A, 107, pp.1437~1442 (2010)[DOI]
59. Aerne BL, "Hippo Stabilises Its Adaptor Salvador by Antagonising the HECT Ubiquitin Ligase Herc4", PLoS One, 10, pp.e0131113~ (2015)[DOI]
60. Poon CL, "The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway", Dev Cell, 21, pp.896~906 (2011)[DOI]
61. Boggiano JC, "Tao-1 phosphorylates Hippo", MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway, 2011, pp.21, 888~895
62. Praskova M, "Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras", Biochem J, 381, pp.453~462 (2004)[DOI]
63. Yuan Z, "Phosphoinositide 3-kinase", Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120, 2010, pp.285, 3815~3824
64. Collak FK, "Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase", Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1, 2012, pp.287, 23698~23709
65. Xiao L, "The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death", J Neurosci, 31, pp.9611~9619 (2011)[DOI]
66. Chen Y, "CYLD negatively regulates Hippo signaling by limiting Hpo phosphorylation in Drosophila", Biochem Biophys Res Commun, 452, pp.808~812 (2014)[DOI]
67. Rodriguez-Boulan E, "Morphogenesis of the polarized epithelial cell phenotype", Science, 245, pp.718~725 (1989)[DOI]
68. Gumbiner BM, "Cell adhesion: the molecular basis of tissue architecture and morphogenesis", Cell, 84, pp.345~357 (1996)[DOI]
69. Chen CL, "The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila", Proc Natl Acad Sci U S A, 107, pp.15810~15815 (2010)[DOI]
70. Ling C, "The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded", Proc Natl Acad Sci U S A, 107, pp.10532~10537 (2010)[DOI]
71. Varelas X, "The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway", Dev Cell, 19, pp.831~844 (2010)[DOI]
72. Robinson BS, "Crumbs regulates Salvador", Warts, Curr Biol, pp.2010, 20[DOI]
73. Ribeiro P, "Crumbs promotes expanded recognition and degradation by the SCF(Slimb", beta-TrCP) ubiquitin ligase, 2014, pp.111, E1980~E19809

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