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카페시타빈 복용 중인 대장암 환자의 발 통증: 수족증후군과 통풍의 감별

Differential Diagnosis between Hand-foot Syndrome and Gout in Colorectal Cancer with Capecitabine: A Case Study and Review of the Literature

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초록

This study is to present a case of a patient experiencing foot pain after being prescribed capecitabine and to review the differentialdiagnosis between hand-foot syndrome and gout. Methods: This case is an 89-year-old patient endorsed to an emergencydepartment with a 2-day history of foot swelling and pain. Results: The old patient was treated with capecitabine which was orally administeredtwice daily for 2 weeks, followed by 1 week of rest. He experienced severe pain in his foot area during the 3rd chemotherapycycle. Side effects must be assessed to keep treatment on course. Conclusion: Clinical specialists should be knowledgeable of differentialdiagnosis.

Abstract

This study is to present a case of a patient experiencing foot pain after being prescribed capecitabine and to review the differentialdiagnosis between hand-foot syndrome and gout. Methods: This case is an 89-year-old patient endorsed to an emergencydepartment with a 2-day history of foot swelling and pain. Results: The old patient was treated with capecitabine which was orally administeredtwice daily for 2 weeks, followed by 1 week of rest. He experienced severe pain in his foot area during the 3rd chemotherapycycle. Side effects must be assessed to keep treatment on course. Conclusion: Clinical specialists should be knowledgeable of differentialdiagnosis.

참고문헌 (8)

  1. 홍용상, "대장직장암의 항암화학요법", 대한의사협회지, 53(7), pp.582~591 (2010), 대한의사협회
  2. 정지민, "고령 대장암 환자에서 수술 시행에 따른 생존율의 차이와 위험인자 분석", 대한내과학회지, 76(6), pp.701~712 (2009), 대한내과학회
  3. Neuman HB, "Surgical treatment of colon cancer in patients aged 80 years and older", Cancer, 119(3), pp.639~647 (2013)
  4. Yarbro CH, "Cancer symptom management" (2014), Jones & Bartlett Learning
  5. Abushullaih S, "Incidence and severity of hand-foot syndrome in colorectal cancer patients treated with capecitabine: a single-institution experience", Cancer Investigation, 20(1), pp.3~10 (2002)
  6. Common Terminology Criteria for Adverse Events (CTCAE) Version 4.0, "U.S. Department of Health and Human Services", National Cancer Institute, ~, pp.National Cancer Institute No. 09-5410 (2009)
  7. 송정수, "통풍의 임상증상과 진단", 대한의사협회지, 53(8), pp.695~704 (2010), 대한의사협회
  8. 서영일, "한국인 통풍 환자의 진단 및 치료 실태 조사", 대한류마티스학회지, 18(3), pp.187~192 (2011), 대한류마티스학회

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