항암화학요법을 받는 암 환자의 말초신경병증 영향요인
Factors Influencing Peripheral Neuropathy of Cancer Patients Undergoing Chemotherapy
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Purpose: We conducted a descriptive study to identify the factors affecting peripheral neuropathy in cancer patients undergoing chemotherapy. Methods: Data were collected from 131 cancer patients who underwent chemotherapy at two university hospitals in D city from January to July in 2018. The instruments used were the European Organization for Research and Treatment of Cancer-Chemotherapy Induced Peripheral Neuropathy 20 (EORTC-QLQ CIPN 20), International Physical Activity Questionnaire (IPAQ), nutrition and eating habits, and Hospital Anxiety & Depression Scale (HADS). Results: Factors influencing peripheral neuropathy in cancer patients undergoing chemotherapy were gender (β=-0.34, p=.005), basal cold hypersensitivity in the hands and feet (β=0.29, p<.001), depression (β=0.27, p=.002), and diabetes (β=0.23, p<.001). The explanatory power of the model was 41.1%. Conclusion: Based on the results of the study, it is necessary to plan nursing interventions for cancer patients undergoing chemotherapy with peripheral neuropathy by considering gender, cold hypersensitivity in the hands and feet, depression, and diabetes.
Abstract
Purpose: We conducted a descriptive study to identify the factors affecting peripheral neuropathy in cancer patients undergoing chemotherapy. Methods: Data were collected from 131 cancer patients who underwent chemotherapy at two university hospitals in D city from January to July in 2018. The instruments used were the European Organization for Research and Treatment of Cancer-Chemotherapy Induced Peripheral Neuropathy 20 (EORTC-QLQ CIPN 20), International Physical Activity Questionnaire (IPAQ), nutrition and eating habits, and Hospital Anxiety & Depression Scale (HADS). Results: Factors influencing peripheral neuropathy in cancer patients undergoing chemotherapy were gender (β=-0.34, p=.005), basal cold hypersensitivity in the hands and feet (β=0.29, p<.001), depression (β=0.27, p=.002), and diabetes (β=0.23, p<.001). The explanatory power of the model was 41.1%. Conclusion: Based on the results of the study, it is necessary to plan nursing interventions for cancer patients undergoing chemotherapy with peripheral neuropathy by considering gender, cold hypersensitivity in the hands and feet, depression, and diabetes.
참고문헌 (29)
- "Statistics of cancer"[URL]
- 이세영, "발반사요법이 항암화학요법 관련 말초신경병증, 증상 디스트레스, 불안 및 우울에 미치는 효과", Asian Oncology Nursing, 12(4), pp.305~313 (2012), 대한종양간호학회[DOI]
- Tofthagen CS, "Development and psychometric evaluation of the chemotherapy-induced peripheral neuropathy assessment tool", Cancer Nurs, 34(4), pp.E10~E20 (2011)
- Quasthoff S, "Chemotherapy-induced peripheral neuropathy", J Neurol, 249(1), pp.9~17 (2002)
- Miltenburg N, "Chemotherapy-induced neuropathy: a comprehensive survey", Cancer Treat Rev, 40(7), pp.872~882 (2014)
- 곽미경(Kwak, Mi Kyong), "항암화학요법으로 인한 암환자의 말초신경병증 관련 특성과 삶의 질", Asian Oncology Nursing, 10(2), pp.231~239 (2010), 대한종양간호학회
- Bao T, "Long-term chemotherapy-induced peripheral neuropathy among breast cancer survivors: prevalence, risk factors, and fall risk", Breast Cancer Res Treat, 159(2), pp.327~333 (2016)
- Boehmke MM, "Symptom, symptom experiences, and symptom distress encountered by women with breast cancer undergoing current treatment modalities", Cancer Nurs, 28(5), pp.382~389 (2005)
- Grisold W, "Peripheral neuropathies from chemotherapeutics and targeted agents: diagnosis, treatment, and prevention", Neuro Oncol, 14(4), pp.45~54 (2012)
- Vincenzi B, "Identification of clinical predictive factors of oxaliplatin-induced chronic peripheral neuropathy in colorectal cancer patients treated with adjuvant Folfox IV", Support Care Cancer, 21, pp.1313~1319 (2013)
- Han JW, "A study on type of chemotherapy-induced peripheral neuropathy symptom, influencing factors, and functional status", master, pp.2014
- Pereira S, "Chemotherapy-induced peripheral neuropathy after neoadjuvant or adjuvant treatment of breast cancer: a prospective cohort study", Support Care Cancer, 24(4), pp.1571~1581 (2016)
- Reyes-Gibby CC, "Chemotherapy-induced peripheral neuropathy as a predictor of neuropathic pain in breast cancer patients previously treated with paclitaxel", J Pain, 10(11), pp.1146~1150 (2009)
- Hershman DL, "Association between patient reported outcomes and quantitative sensory tests for measuring long-term neurotoxicity in breast cancer survivors treated with adjuvant paclitaxel chemotherapy", Breast Cancer Res Treat, 125(3), pp.767~774 (2011)
- Greenlee H, "BMI, lifestyle factors and taxane-induced neuropathy in breast cancer patients: The pathways study", J Natl Cancer Inst, 109(2), pp.1~8 (2017)
- Derksen TM, "Lifestyle-related factors in the self-management of chemotherapy-induced peripheral neuropathy in colorectal cancer: a systemic review", Evid Based Complement Alternat Med, pp.1~14 (2017)
- 한상숙, "Oxaliplatin을 투여 받는 대장암 환자의 우울, 불안, 사회적지지, 항암제 지식수준이 말초신경병증에 미치는 영향", 임상간호연구, 19(2), pp.298~308 (2013), 병원간호사회
- Jang JB, "Study on the definition of the female’s partcoldness syndrome", J Korean Med, 15(2), pp.397~411 (1994)
- Park SO, "Dietary and socioeconomic factors that influence on the intake of B vitamins in pregnant women", master, pp.2003
- Choi JI, "A study on diet and nutritional status of breast cancer patient", master, pp.2005
- Tofthagen C, "Self-management of oxaliplatin-related peripheral neuropathy in colorectal cancer survivors", Chemother Res Pract, 2013(1), pp.1~7 (2013)
- 오지연, "한국어판 단문형 국제신처활동설문(IPAQ)의 신뢰도와 타당도", Korean Journal of Family Medicine, 28(7), pp.532~541 (2007), 대한가정의학회
- Zigmond AS, "The hospital anxiety and depression scale", Acta Psychiatr Scand, 67(6), pp.361~370 (1983)
- Oh SM, "A study on the standardization of the Hospital Anxiety Depression Scale for Koreans: a comparison of normal, depressed and anxious groups", J Korean Neuropsychiatr Assoc, 38(2), pp.289~296 (1999)
- Kim HM, "Symptoms and relief therapy related to chemotherapy induced peripheral neuropathy in patients with cancer", master, pp.2012
- 박유리, "항암화학요법을 받는 암환자의 말초신경병증 정도, 자아통제감과 삶의 질의 관계", 석사, 간호학과 임상간호학전공, pp.2014
- Goveas JS, "Depressive symptoms and incidence of mild cognitive impairment and probable dementia in elderly women: the women’s health initiative memory study", J Am Geriatr Soc, 59(1), pp.57~66 (2011)
- Altaf R, "Incidence of cold-induced peripheral neuropathy and dose modification of adjuvant oxaliplatinbased chemotherapy for patients with colorectal cancer", Oncology, 87(3), pp.167~172 (2014)
- Pop-Busui R, "Diabetic neuropathy: a position statement by the American Diabetes Association", Diabetes Care, 40(1), pp.136~154 (2017)