부인암 환자의 말초신경병증과 삶의 질
Characteristics and Quality of Life in Gynecologic Cancer Patients with Chemotherapy-induced Peripheral Neuropathy
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초록
Purpose: The purpose of this study was to identify chemotherapy induced peripheral neuropathy, quality of life of patients with gynecologic cancer. Methods: This was a cross-sectional survey design. We collected 130 patients with gynecologic cancer. They complete a self reported questionnaire including items related neuropathy and quality of life (FACT-GOG/Ntx subscale, FACT-G scale). Results: The neuropathy score was 14.3±7.9. The quality of life score was 64.8±16.4. The neuropathy induced significant difference according to diabetic status, difficulties in performing household chores and willing to discontinuity of chemotherapy. And duration of cancer diagnosis, neuropathy,number of total chemo agent associated with quality of life. There was a negative correlation between number of total chemo agent and quality of life. Neuropathy independently affected quality of life. Conclusion: Chemotherapy induced peripheral neuropathy of patients with gynecologic cancer adversely affected women’s quality of life and activities of daily living. To improve patient’s quality of life, it is important that accurate assess and appropriately manage neuropathy in patients with gynecologic cancer
Abstract
Purpose: The purpose of this study was to identify chemotherapy induced peripheral neuropathy, quality of life of patients with gynecologic cancer. Methods: This was a cross-sectional survey design. We collected 130 patients with gynecologic cancer. They complete a self reported questionnaire including items related neuropathy and quality of life (FACT-GOG/Ntx subscale, FACT-G scale). Results: The neuropathy score was 14.3±7.9. The quality of life score was 64.8±16.4. The neuropathy induced significant difference according to diabetic status, difficulties in performing household chores and willing to discontinuity of chemotherapy. And duration of cancer diagnosis, neuropathy,number of total chemo agent associated with quality of life. There was a negative correlation between number of total chemo agent and quality of life. Neuropathy independently affected quality of life. Conclusion: Chemotherapy induced peripheral neuropathy of patients with gynecologic cancer adversely affected women’s quality of life and activities of daily living. To improve patient’s quality of life, it is important that accurate assess and appropriately manage neuropathy in patients with gynecologic cancer
참고문헌 (27)
- Bakitas, M. A., "Background noise: The experience of chemotherapy- induced peripheral neuropathy", Nursing Research, 56, pp.323~331 (2007)
- Bartlett, J. E., "Organizational research: Determining appropriate sample size in survey research", Information Technology, Learning, and Performance Journal, 19, pp.43~50 (2001)
- Berek, J. S., "Berek & Novak's Gynecology" (2007), Lippincott
- Calhoun, E. A., "Psychometric evaluation of functional assessment of cancer therapy", gynecologic oncology group-neurotoxicity(FACT, International Journal of Gynecologic Oncology, pp.2003, 13[DOI]
- Cella, D., "Manual of the functional assessment of chronic illness therapy (FACIT) measurement system", Center on outcomes, research and education (CORE), Evanston Northwestern Healthcare and Northwestern University, ~ (1997)
- Hausheer, F. H., "Diagnosis, management, and evaluation of chemotherapy induced peripheral neuropathy", Seminars in Oncology, 33, pp.15~49 (2006)
- Kaley, T. J., "Therapy of chemotherapyinduced peripheral neuropathy", British Journal of Haematology, 145, pp.3~14 (2009)
- Kim, H. M., "Symptoms and relief therapy related to chemotherapy induced peripheral neuropathy in patients with cancer", 석사, pp.2012
- 김정혜, "항암화학요법으로 인한 말초신경병증을 경험하는 대장암 환자의 삶의 질", Asian Oncology Nursing, 11(3), pp.254~262 (2011), 대한종양간호학회
- Kiser, D. W., "Peripheral neuropathy in patients with gynecologic cancer receiving chemotherapy: Patient reports and provider assessments", Oncology Nursing Forum, 37, pp.758~764 (2010)
- 곽미경(Kwak, Mi Kyong), "항암화학요법으로 인한 암환자의 말초신경병증 관련 특성과 삶의 질", Asian Oncology Nursing, 10(2), pp.231~239 (2010), 대한종양간호학회
- Long, H. J., "Clinical results and quality of life analysis for the MVAC combination (methotrexate, vinblastine, doxorubicin, and cisplatin) in carcinoma of the uterine cervix: A gynecologic oncology group study", Gynecologic Oncology, 100, pp.537~543 (2006)
- Mantyh, P. W., "Cancer pain and its impact on diagnosis, survival and quality of life", Nature Reviews Neuroscience, 7, pp.797~809 (2006)
- Pan, Y., "Discordance of clinical symptoms and electrophysiologic findings in taxane plus platinum-induced neuropathy", International Journal of Gynecological Cancer, 17, pp.394~397 (2007)
- 박애령, "진행성 또는 전이성 위암 환자에 있어서 Oxaliplatin 투여로 인한 말초신경통증 분석", 한국임상약학회지, 19(1), pp.18~22 (2009), 한국임상약학회
- Rao, R. D., "Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy: A phase 3 randomized, double-blind, placebo-controlled, cross-over trial", Cancer, 110, pp.2110~2118 (2007)
- Smith, E. L., "Quality improvement of painful peripheral neuropathy", Seminars in Oncology Nursing, 18, pp.36~43 (2002)
- Smith, E. M., "The total neuropathy score: A tool for measuring chemotherapy-induced peripheral neuropathy", Oncology Nursing Forum, 35, pp.96~102 (2008)
- "Cancer occurrence ratio in Korea women" (2010)[URL]
- Sweeney, C. W., "Understanding peripheral neuropathy in patients with cancer: Background and patients assessment", Clinical Journal of Oncology Nursing, 6, pp.163~166 (2002)
- Tofthagen, C., "Patient perceptions associated with chemotherapy- induced peripheral neuropathy", Clinical Journal of Oncology Nursing, 14, pp.E22~E28 (2010)
- Tofthagen, C., "Peripheral neuropathy in patients with colorectal cancer receiving oxaliplatin", Clinical Journal of Oncology Nursing, 15, pp.182~188 (2011)
- Verstappen, C. C., "Neurotoxic complication of chemotherapy in patients with cancer: Clinical signs and optimal management", Drugs, 63, pp.1549~1563 (2003)
- Viens, P., "A phase II study of a paclitaxel and oxaliplatin combination in platinum-sensitive recurrent advanced ovarian cancer patients", Annuals of Oncology, 17, pp.429~436 (2006)
- Wickham, R., "Chemotherapy-induced peripheral neuropathy: A review and implications for oncology nursing practice", Clinical Journal of Oncology Nursing, 11, pp.361~376 (2007)
- Wolf, S., "Chemotherapy-induced peripheral neuropathy: Prevention and treatment strategies", European Journal of Cancer, 44, pp.1507~1515 (2008)
- Yarbro, C. H., "Cancer symptom management" (2004), Jones and Bartlett
