파장별 지표 자외선 복사량을 이용한 SARS-CoV-2 바이러스 비활성화 시간 추정 연구
Estimation of the SARS-CoV-2 Virus Inactivation Time Using Spectral Ultraviolet Radiation
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Corona Virus Disease 19 pandemic (COVID-19) causes many deaths worldwide, and has enormous impacts on society and economy. The COVID-19 was caused by a new type of coronavirus (Severe Acute Respiratory Syndrome Cornonavirus 2; SARS-CoV-2), which has been found that these viruses can be effectively inactivated by ultraviolet (UV) radiation of 290~315 nm. In this study, 90% inactivation time of the SARS-CoV-2 virus was analyzed using ground observation data from Brewer spectrophotometer at Yonsei University, Seoul and simulation data from UVSPEC for the period of 2015~2017 and 2020. Based on 12:00-13:00 noon time, the shortest virus inactivation time were estimated as 13.5 minutes in June and 4.8 minutes in July/August, respectively, under all sky and clear sky conditions. In the diurnal and seasonal variations, SARS-CoV-2 could be inactivated by 90% when exposed to UV radiation within 60 minutes from 10:00 to 14:00, for the period of spring to autumn. However, in winter season, the natural prevention effect was meaningless because the intensity of UV radiation weakened, and the time required for virus inactivation increased. The spread of infectious diseases such as COVID-19 is related to various and complex interactions of several variables, but the natural inactivation of viruses by UV radiation presented in this study, especially seasonal differences, need to be considered as major variables.
Abstract
Corona Virus Disease 19 pandemic (COVID-19) causes many deaths worldwide, and has enormous impacts on society and economy. The COVID-19 was caused by a new type of coronavirus (Severe Acute Respiratory Syndrome Cornonavirus 2; SARS-CoV-2), which has been found that these viruses can be effectively inactivated by ultraviolet (UV) radiation of 290~315 nm. In this study, 90% inactivation time of the SARS-CoV-2 virus was analyzed using ground observation data from Brewer spectrophotometer at Yonsei University, Seoul and simulation data from UVSPEC for the period of 2015~2017 and 2020. Based on 12:00-13:00 noon time, the shortest virus inactivation time were estimated as 13.5 minutes in June and 4.8 minutes in July/August, respectively, under all sky and clear sky conditions. In the diurnal and seasonal variations, SARS-CoV-2 could be inactivated by 90% when exposed to UV radiation within 60 minutes from 10:00 to 14:00, for the period of spring to autumn. However, in winter season, the natural prevention effect was meaningless because the intensity of UV radiation weakened, and the time required for virus inactivation increased. The spread of infectious diseases such as COVID-19 is related to various and complex interactions of several variables, but the natural inactivation of viruses by UV radiation presented in this study, especially seasonal differences, need to be considered as major variables.
참고문헌 (38)
- Armstrong, B. K., "The epidemiology of UV induced skin cancer", J. Photochem. photobiol. B, 63, pp.8~18 (2001)
- Diffey, B. L., "Solar ultraviolet radiation effects on biological systems", Phys. Med. Biol, 36, pp.299~ (1991)
- El-Ghorr, A. A., "The effect of UV-B irradiation on secondary epidermal infection of mice with herpes simplex virus type 1", J. Gen. Virol, 77, pp.485~491 (1996)
- Claudia Emde, "The libRadtran software package for radiative transfer calculations (version 2.0.1)", Geoscientific Model Development, 9(5), pp.1647~1672 (2016), Copernicus GmbH[DOI]
- Fioletov, V. E., "The Brewer reference triad. Geophys", Res. Lett, 32, pp.L20805~ (2005)
- Galkin, O. N., "‘Vitamin D’biodosimeter : basic characteristics and potential applications", J. Photoch. Photobio. B, 53, pp.12~19 (1999)
- Gröbner, J., "Aerosol optical depth in the UVB and visible wavelength range from Brewer spectrophotometer direct irradiance measurements:1991~2002", J. Geophys. Res. Atmos, 109, pp.D09202~ (2002)
- Harm, W., "Biological effects of ultraviolet radiation", pp.229~ (1980), Cambridge University Press
- Jay Herman, "Inactivation times from 290 to 315 nm UVB in sunlight for SARS coronaviruses CoV and CoV-2 using OMI satellite data for the sunlit Earth", Air Quality, Atmosphere & Health, 14(2), pp.217~233 (2020), Springer Science and Business Media LLC[DOI]
- Michael F. Holick, "Vitamin D Deficiency", New England Journal of Medicine, 357(3), pp.266~281 (2007), Massachusetts Medical Society[DOI]
- Tomi Karppinen, "Brewer spectrometer total ozone column measurements in Sodankylä", Geoscientific Instrumentation, Methods and Data Systems, 5(1), pp.229~239 (2016), Copernicus GmbH[DOI]
- Kerr, J. B., "Evidence for large upward trends of ultraviolet-B radiation linked to ozone depletion", Science, 262, pp.1032~1034 (1993)
- Jhoon Kim, "Effects of ozone and aerosol on surface UV radiation variability", Journal of Photochemistry and Photobiology B: Biology, 119, pp.46~51 (2013), Elsevier BV[DOI]
- Jiyoung Kim, "Intercomparison of total column ozone data from the Pandora spectrophotometer with Dobson, Brewer, and OMI measurements over Seoul, Korea", Atmospheric Measurement Techniques, 10(10), pp.3661~3676 (2017), Copernicus GmbH[DOI]
- Kim, J. E., "Temporal variation and measurement uncertainty of UV aerosol optical depth measured from April 2002 to July 2004 at Gwangju, Korea", Atmos. Res, 81, pp.111~123 (2006)
- Songkang Kim, "Evaluation of Total Ozone Column from Multiple Satellite Measurements in the Antarctic Using the Brewer Spectrophotometer", Remote Sensing, 13(8), pp.1594~ (2021), MDPI AG[DOI]
- Woogyung Kim, "UV Sensitivity to Changes in Ozone, Aerosols, and Clouds in Seoul, South Korea", Journal of Applied Meteorology and Climatology, 53(2), pp.310~322 (2014), American Meteorological Society[DOI]
- Lee, J. E., "Norovirus and MS2 inactivation kinetics of UV-A and UV-B with and without TiO2", Water Res, 47, pp.5607~5613 (2013)[DOI]
- Yanping Lin, "Enhancement of Vitamin D Metabolites in the Eye Following Vitamin D3 Supplementation and UV-B Irradiation", Current Eye Research, 37(10), pp.871~878 (2012), Informa UK Limited[DOI]
- Javier López-Solano, "Aerosol optical depth in the European Brewer Network", Atmospheric Chemistry and Physics, 18(6), pp.3885~3902 (2018), Copernicus GmbH[DOI]
- R. M. Lucas, "The consequences for human health of stratospheric ozone depletion in association with other environmental factors", Photochemical & Photobiological Sciences, 14(1), pp.53~87 (2014), Springer Science and Business Media LLC[DOI]
- Matsumura, Y., "Toxic effects of ultraviolet radiation on the skin", Toxicol. Appl. Pharmacol, 195, pp.298~308 (2004)
- Mayer, B., "Technical note : The libRadtran software package for radiative transfer calculations-description and examples of use", Atmos. Chem. Phys, 5, pp.1855~1877 (2005)
- Fabrizio Nicastro, "Solar UV-B", A radiation is highly effective in inactivating SARS-CoV-2, 2021, pp.11(1), ~[DOI]
- Raymond Nims, "Inactivation of Caliciviruses", Pharmaceuticals, 6(3), pp.358~392 (2013), MDPI AG[DOI]
- Mary Norval, "Is the action spectrum for the UV-induced production of previtamin D3 in human skin correct?", Photochemical & Photobiological Sciences, 9(1), pp.11~17 (2010), Springer Science and Business Media LLC[DOI]
- Sang Seo Park, "Impact of UV-A radiation on erythemal UV and UV-index estimation over Korea", Advances in Atmospheric Sciences, 32(12), pp.1639~1646 (2015), Springer Science and Business Media LLC[DOI]
- Sang Park, "Estimating Cloud and Aerosol UV Modification Factors Based on Spectral Measurement from the Brewer Spectrophotometer", Atmosphere, 8(6), pp.109~ (2017), MDPI AG[DOI]
- Sang Seo Park, "Simulation of Threshold UV Exposure Time for Vitamin D Synthesis in South Korea", Advances in Meteorology, 2019, pp.1~15 (2019), Hindawi Limited[DOI]
- Pecson, B. M., "Quantitative PCR for determining the infectivity of bacteriophage MS2 upon inactivation by heat, UV-B radiation, and singlet oxygen : advantages and limitations of an enzymatic treatment to reduce false-positive results", Appl. Environ. Microb, 75, pp.5544~5554 (2009)
- Shanna Ratnesar-Shumate, "Simulated Sunlight Rapidly Inactivates SARS-CoV-2 on Surfaces", The Journal of Infectious Diseases, 222(2), pp.214~222 (2020), Oxford University Press (OUP)[DOI]
- Franz‐Xaver Schmid, "Biological Macromolecules: UV‐visible Spectrophotometry", eLS (2001), Wiley[DOI]
- Stringham, J. M., "Action spectrum for photophobia", J. Opt. Soc. Am. A, 20, pp.1852~1858 (2003)
- Meg Watson, "Ultraviolet Radiation Exposure and Its Impact on Skin Cancer Risk", Seminars in Oncology Nursing, 32(3), pp.241~254 (2016), Elsevier BV[DOI]
- Vitamin D and Cancer, "WHO", World Health Organization, International Agency for Research on Cancer, 210~, pp.IARC Working Group Report 5 (2008)
- Young, A. R., "Acute effects of UVR on human eyes and skin", Prog. Biophys. Mol. Bio, 92, pp.80~85 (2006)
- Antony R. Young, "A revised action spectrum for vitamin D synthesis by suberythemal UV radiation exposure in humans in vivo", Proceedings of the National Academy of Sciences, 118(40) (2021), Proceedings of the National Academy of Sciences[DOI]
- Xiaoyi Zhao, "Assessing the impact of clouds on ground-based UV–visible total column ozone measurements in the high Arctic", Atmospheric Measurement Techniques, 12(4), pp.2463~2483 (2019), Copernicus GmbH[DOI]
