항암화학요법을 받는 입원 암환자의 특성에 따른 구내염 정도 차이
Difference of Oral Mucositis in Hospitalized Cancer Patients Receiving Chemotherapy
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Purpose: This study was designed to investigate the difference of oral mucositis in hospitalized cancer patients receiving chemotherapy according to characteristics. Methods: Data were collected from March 1 to April 25 2012 using questionnaires, and the participants were 177. The Oral Assessment Guide (OAG) by observation and The Oral Mucositis Daily Questionnaire (OMDQ) by selfreport were used to measure oral mucositis. The data were analyzed using SPSS 18.0. Results: Moderate to severe oral mucositis measured by OAG observation were 94.9% in hospitalized cancer patients receiving chemotherapy, frequently complaints of mouth and throat soreness measured by OMDQ was 42.4%, and intensity of mouth and throat soreness measured by OMDQ was 0.65 out of 10. There were statistically significant differences in the prevalence of oral mucositis according to nutrition state, frequency of chemotherapy,experience of oral examination, combination treatment, and number of chemotherapeutic agents. Conclusion: Many hospitalized cancer patients receiving chemotherapy experienced oral mucositis. Cancer patients receiving chemotherapy with poor nutritional status, more frequent chemotherapy and combination treatments should have a more meticulous oral care. So there needs to be an appropriate assessment tool and prevention protocol for oral mucositis that considers related factors.
Abstract
Purpose: This study was designed to investigate the difference of oral mucositis in hospitalized cancer patients receiving chemotherapy according to characteristics. Methods: Data were collected from March 1 to April 25 2012 using questionnaires, and the participants were 177. The Oral Assessment Guide (OAG) by observation and The Oral Mucositis Daily Questionnaire (OMDQ) by selfreport were used to measure oral mucositis. The data were analyzed using SPSS 18.0. Results: Moderate to severe oral mucositis measured by OAG observation were 94.9% in hospitalized cancer patients receiving chemotherapy, frequently complaints of mouth and throat soreness measured by OMDQ was 42.4%, and intensity of mouth and throat soreness measured by OMDQ was 0.65 out of 10. There were statistically significant differences in the prevalence of oral mucositis according to nutrition state, frequency of chemotherapy,experience of oral examination, combination treatment, and number of chemotherapeutic agents. Conclusion: Many hospitalized cancer patients receiving chemotherapy experienced oral mucositis. Cancer patients receiving chemotherapy with poor nutritional status, more frequent chemotherapy and combination treatments should have a more meticulous oral care. So there needs to be an appropriate assessment tool and prevention protocol for oral mucositis that considers related factors.
참고문헌 (30)
- "National cancer registration statistics"[URL]
- "Understanding of Cancer"[URL]
- Yabro CH, "Cancer nursing principles and practice" (2000), Jones and Bartlett Publishers
- Viens P, "A phase II study of a paclitaxel and oxaliplatin combination in platinum-sensitive recurrent advanced ovarian cancer patients", Ann Oncol, 17(3), pp.429~436 (2000)
- Bruya MA, "Stomatitis after chemotherapy", Am J Nurs, 75, pp.1349~1352 (1975)
- Turhal NS, "Efficacy of treatment to relieve mucositisinduced discomfort", Support Care Cancer, 8, pp.55~58 (2000)
- Barasch A, "Risk factors for ulcerative oral mucositis in cancer patients : unanswered questions", Oral Oncol, 39(2), pp.91~100 (2003)
- Byeon YS, "The survey of mouth care among cancer patient received chemotherapy", Kor J Fundamentals Nurs, 2(2), pp.115~130 (1995)
- Cheng KF, "Risk factors for oral mucositis in children undergoing chemotherapy : a matchedcase-control study", Oral Oncol, 44, pp.1019~1025 (2008)
- Cheng KF, "Incidence and risk factors of oral mucositis in paediatric and adolescent patients undergoing chemotherapy", Oral Oncol, 47, pp.154~162 (2011)
- Eilers J, "Development, testing and application of the oral assessment guide", Oncol Nurs Forum, 15, pp.325~330 (1988)
- Bellm LA, "Defining clinically meaningful outcomes in the evaluation of new treatments for oral mucositis: oral mucositis patient provider advisory board", Cancer Invest, 20, pp.793~800 (2002)
- Quinn B, "Ensuring accurate oral mucositis assessment in the European group for blood and marrow transplantation prospective oral mucositis audit", Eur J Oncol Nurs, 11, pp.10~18 (2007)
- 최소은, "화학요법을 받는 급성백혈병 환자 자가보고형 구강점막염 사정도구의 신뢰도와 타당도 분석", Journal of korean biological nursing science, 12(3), pp.148~156 (2010), 기초간호학회
- Stiff PJ, "Reliability and validity of a patient silf-administered daily questionnaire to assess impact of oral mucositis(OM)on pain and daily functioning in patient undergoing autologous hematopoietic stem cell transplantation(HSCT)", Bone Marrow Transplant, 37, pp.393~401 (2006)
- 송지은, "급성백혈병 환자를 대상으로 구강함수제별 구내염 및 구강안위감에 대한 무작위대조시험연구", Asian Oncology Nursing, 11(1), pp.33~40 (2011), 대한종양간호학회
- Faber MV, "Philadelphia", pp.311~317 (2000), Lippincott Williams & Wilkins;
- Darwish AM, "Effect of chlorhexidine in prevention of oral lesions in leukemic children receiving chemotherapy", J Am Sci, 7(7), pp.985~996 (2011)
- Fox SW, "Symptom clusters and quality of life in survivors of lung cancer", Oncol Nurs Forum, 33, pp.931~936 (2006)
- Weaver C, "Risk for unplanned hospital readmission of patients with cancer : results of a retrospective medical record review", Oncol Nurs Forum, 33, pp.44~52 (2006)
- Harris DJ, "Putting evidence into practice : Evidence-based interventions for the management of oral mucositis", Clinical J Oncol Nurs, 12, pp.141~152 (2008)
- Chun HW, "Analysis of factors for relationship between oral disease and chronic disease", pp.2011
- Kim HM, "Management of chemotherapy-related toxicity: nutrition support during chemotherapy", Symposium of Kor Socie of Clinical Oncol, 3, pp.23~33 (2005)
- Sonis ST, "Mucositis as a biological process: a new bypothesis for the development of chemotherapy-induced stomatotoxicity", Oral Oncol, 34, pp.39~43 (1998)
- Graham KM, "Reducing the incidence of stomatitis using a quality assessment and improvement approach", Cancer Nurs, 16, pp.117~122 (1993)
- Kim ES, "A study on perceived oral health, oral health promotion and dental impact of daily living", J Korean Acad Dent Health, 24, pp.145~157 (2000)
- Eaton LH, "Putting evidence into practice : improving oncology patient outcomes" (2009), Oncology Nursing Society
- Sonis ST, "Mucositis : The impact, biology and therapeutic opportunities of oral mucositis", Oral Oncol, 45(12), pp.1015~1020 (2009)
- 천순미, "찬 구강함수액이 항암 화학요법 환자의 구강불편감에 미치는 영향", Asian Oncology Nursing, 7(1), pp.68~78 (2007), 대한종양간호학회
- Elting LS, "The burdens of cancer therapy : clinical and economic outcomes of chemotherapy-induced mucositis", Cancer, 98, pp.1531~1539 (2003)