본문 바로가기
KERD
논문KCI 등재

Photobiomodulation Therapy in the Treatment of Salivary Dysfunction

Celine DG. Abueva
대한의학레이저학회 (Korean Society for Laser Medicine and Surgery)|2022.03|Medical Lasers|제11권 제1호|pp. 15-20|DOI 10.25289/ML.2022.11.1.15

1

조회

0

다운로드

1

인용

0

참고문헌

키워드

XerostomiaLow level laser therapyPhotobiomodulationHyposalivationDry mouth
주제분류의학일반

초록

Photobiomodulation therapy, owing to its photobiological anti-inflam-matory and wound healing effects, has been suggested as a non-invasive, safe, and effective approach in treating salivary dysfunctions. Xerostomia or dry mouth and hyposalivation are challenging conditions, and patients suffer oral problems and a poor quality of life. Several studies have demonstrated the potential of photobiomodulation in reducing xerosto-mia and hyposalivation. However, there is a lack of synthesis of available evidence to establish whether it is an efficient, safe, and cost-effective method. In addition, the challenges include the lack of consensus on the optimal PBM dosage, as well as the variability of the findings in published studies.

Abstract

Photobiomodulation therapy, owing to its photobiological anti-inflam-matory and wound healing effects, has been suggested as a non-invasive, safe, and effective approach in treating salivary dysfunctions. Xerostomia or dry mouth and hyposalivation are challenging conditions, and patients suffer oral problems and a poor quality of life. Several studies have demonstrated the potential of photobiomodulation in reducing xerosto-mia and hyposalivation. However, there is a lack of synthesis of available evidence to establish whether it is an efficient, safe, and cost-effective method. In addition, the challenges include the lack of consensus on the optimal PBM dosage, as well as the variability of the findings in published studies.

참고문헌 (35)

  1. Iorgulescu G, "Saliva between normal and pathological. Important factors in determining systemic and oral health", J Med Life, 2, pp.303~307 (2009)
  2. Islas-Granillo H, "Relationship of hyposalivation and xerostomia in Mexican elderly with socioeconomic, sociodemographic and dental factors", Sci Rep, 7, pp.40686~ (2017)
  3. Mese H, "Salivary secretion, taste and hyposalivation", J Oral Rehabil, 34, pp.711~723 (2007)
  4. Ship JA, "Xerostomia and the geriatric patient", J Am Geriatr Soc, 50, pp.535~543 (2002)
  5. Millsop JW, "Etiology, evaluation, and management of xerostomia", Clin Dermatol, 35, pp.468~476 (2017)
  6. Cassolato SF, "Xerostomia : clinical aspects and treatment", Gerodontology, 20, pp.64~77 (2003)
  7. Dirix P, "Radiation-induced xerostomia in patients with head and neck cancer : a literature review", Cancer, 107, pp.2525~2534 (2006)
  8. Tanasiewicz M, "Xerostomia of various etiologies : a review of the literature", Adv Clin Exp Med, 25, pp.199~206 (2016)
  9. Farag AM, "Comparing the effectiveness and adverse effects of pilocarpine and cevimeline in patients with hyposalivation", Oral Dis, 25, pp.1937~1944 (2019)
  10. Al Hamad A, "Interventions for dry mouth and hyposalivation in Sjögren's syndrome : a systematic review and meta-analysis", Oral Dis, 25, pp.1027~1047 (2019)
  11. Heiskanen V, "Photobiomodulation therapy for cancer treatment-related salivary gland dysfunction : a systematic review", Photobiomodul Photomed Laser Surg, 38, pp.340~347 (2020)
  12. Spanemberg JC, "Efficacy of low-level laser therapy for the treatment of burning mouth syndrome : a randomized, controlled trial", J Biomed Opt, 20, pp.098001~ (2015)
  13. Sousa AS, "Photobiomodulation and salivary glands : a systematic review", Lasers Med Sci, 35, pp.777~788 (2020)
  14. Hyun Seok Ryu, "Decade Long Survey of Low-level Laser Therapy", Photobiomodulation (LLLT, Medical Lasers, pp.2021, 10(3)[DOI]
  15. Rhee YH, "Chung PS. Effect of photobiomodulation on wound healing of the corneal epithelium through Rho-GTPase", Med Laser, 6, pp.67~76 (2017)
  16. Ji Won Kang, "Stability and Effectiveness of Laser and Liquiband Treatments in the Rat Model of Oral Ulcer", Medical Lasers, 10(4), pp.207~213 (2021), 대한의학레이저학회[DOI]
  17. de Freitas LF, "Proposed mechanisms of photobiomodulation or low-level light therapy", IEEE J Sel Top Quantum Electron, 22, pp.7000417~ (2016)
  18. Calderhead RG, "Photobiological basics of photomedicine : a work of art still in progress", Med Laser, 6, pp.45~57 (2017)
  19. Biswas R, "Low-level laser therapy with 850 nm recovers salivary function via membrane redistribution of aquaporin 5 by reducing intracellular Ca2+ overload and ER stress during hyperglycemia", Biochim Biophys Acta Gen Subj, 1862, pp.1770~1780 (2018)
  20. Plavnik LM, "Effect of low-power radiation(helium", neon)upon submandibulary glands, 2003, pp.21, 219~225
  21. Fukuoka CY, "The effects of low-power laser irradiation on inflammation and apoptosis in submandibular glands of diabetes-induced rats", PLoS One, 12, pp.e0169443~ (2017)
  22. Louzeiro GC, "Does laser photobiomodulation prevent hyposalivation in patients undergoing head and neck radiotherapy? A systematic review and meta-analysis of controlled trials", Crit Rev Oncol Hematol, 156, pp.103115~ (2020)
  23. Konings AW, "On the mechanism of salivary gland radiosensitivity", Int J Radiat Oncol Biol Phys, 62, pp.1187~1194 (2005)
  24. Avila JL, "Radiationinduced salivary gland dysfunction results from p53-dependent apoptosis", Int J Radiat Oncol Biol Phys, 73, pp.523~529 (2009)
  25. Jensen SB, "A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies:prevalence, severity and impact on quality of life", Support Care Cancer, 18, pp.1039~1060 (2010)
  26. Louzeiro GC, "Effect of photobiomodulation on salivary flow and composition, xerostomia and quality of life of patients during head and neck radiotherapy in short term follow-up : a randomized controlled clinical trial", J Photochem Photobiol B, 209, pp.111933~ (2020)
  27. Palma LF, "Impact of low-level laser therapy on hyposalivation, salivary pH, and quality of life in head and neck cancer patients post-radiotherapy", Lasers Med Sci, 32, pp.827~832 (2017)
  28. Libik TV, "Management of cancer therapy-induced oral mucositis pain and xerostomia with extra-and intra oral laser irradiation", AIP Conf Proc, 1882, pp.020044~ (2017)
  29. Gonnelli FA, "Low-level laser for mitigation of low salivary flow rate in head and neck cancer patients undergoing radiochemotherapy : a prospective longitudinal study", Photomed Laser Surg, 34, pp.326~330 (2016)
  30. Oton-Leite AF, "Effect of low level laser therapy in the reduction of oral complications in patients with cancer of the head and neck submitted to radiotherapy", Spec Care Dentist, 33, pp.294~300 (2013)
  31. de Oliveira AB, "Photobiomodulation in the treatment of xerostomia associated with hyposalivation in a pediatric patient with systemic scleroderma", Autops Case Rep, 11, pp.e2020220~ (2020)
  32. Terlević Dabić D, "The effectiveness of low-level laser therapy in patients with drug-induced hyposalivation : a pilot study", Photomed Laser Surg, 34, pp.389~393 (2016)
  33. Bardellini E, "Efficacy of the photobiomodulation therapy in the treatment of the burning mouth syndrome", Med Oral Patol Oral Cir Bucal, 24, pp.e787~e791 (2019)
  34. Barbosa NG, "Evaluation of laser therapy and alpha-lipoic acid for the treatment of burning mouth syndrome : a randomized clinical trial", Lasers Med Sci, 33, pp.1255~1262 (2018)
  35. Fidelix T, "Low-level laser therapy for xerostomia in primary Sjögren's syndrome : a randomized trial", Clin Rheumatol, 37, pp.729~736 (2018)

관련 논문AI추천

Decade Long Survey of Low-level Laser Therapy/ Photobiomodulation (LLLT/PBM) Therapy for Oral Mucositis Treatment류현석, 우승훈, Celine Abueva, Phil-Sang Chung대한의학레이저학회 · Medical Lasers2021 · 제10권 제3호Photobiomodulation and implants: implications for dentistryElieza Tang, Praveen Arany대한치주과학회 · Journal of Periodontal & Implant Science2013 · 제43권 제6호Photobiomodulation for immunomodulation and inflammation control: evidence from cellular, animal, and clinical researchHyun Seok Ryu, Seung Hoon Woo, Yong Seok Lee대한의학레이저학회 · Medical Lasers2025 · 제14권 제2호Photobiomodulation Therapy in Recovery of Peripheral Facial Nerve Damage최지은대한의학레이저학회 · Medical Lasers2020 · 제9권 제2호A review on photobiomodulation therapy for olfactory dysfunction caused by COVID-19Reiza Dolendo Ventura대한의학레이저학회 · Medical Lasers2022 · 제11권 제2호구강건조증에 대한 경피적전기신경자극(Transcutaneous electrical nerve stimulation)의 최근 임상연구 동향 고찰 - Pubmed와 국내 논문을 중심으로고석재, 김민정, 박재우, 이은경, 전혜진대한한방내과학회 · 대한한방내과학회지2022 · 제43권 제3호

이 간행물의 다른 논문 (9건)

Review of Scar Assessment ScalesWon-Serk Kim, 김범준, Jaeyoung Kim, You Na Jang, Jung Ok Lee, Hyun Ho Yoo, Young Gue Koh, Jae Wan Park, Young-Jun Choi, Sun Hye Shin, 이갑석, 유광호pp. 1-7Appraisal of Recent Developments in Combined Photodynamic Treatment (PDT)/Photobiomodulation (PBM) for Dermal Wound HealingAndrew Padalhinpp. 8-14A Pilot Study to Assess the Efficacy and Safety of an Intelligent Approach to Noninvasive Body Core Strengthening with a Novel Functional Magnetic Muscle Stimulation (FMS) SystemSojung Kimpp. 21-30Pore and Acne Scar Treatment with a Q-switched Laser Using a Novel Fractional MDF (Multi-depth Focusing) Handpiece: A Pilot StudyJewan Kaiser Hwang, HeeChul Lee, JinYoung Parkpp. 31-39A Comparison of the Effects of Solid-state Lasers on Normal Guinea-pig Muscle and Skin: Using 532 nm Flashlamp-excited and Diode-excited LasersHae Ryung Choi, Phil Sang Chung, Gil Jae Jung, Yoon Ah Kim, 우승훈, 김종수, 이상준pp. 40-46
원문 보기