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불소를 함유한 PVA 고분자 접착 테잎의 불소 유리 효과

THE FLUORIDE RELEASING EFFECT OF PVA FLUORIDE-POLYMER ADHESIVE TAPE

이상호|이난영|임성옥|박승효
대한소아치과학회 (The Korean Academy Of Pediatric Dentistry)|2011.11|대한소아치과학회지 (Journal of the Korean academy of pediatric dentistry)|제38권 제4호|pp. 327-336

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참고문헌

키워드

Fluoride varnish불소 테잎불소바니쉬불소 이온 농도폴리비닐알코올비자극성 전타액Fluoride tapeFluoride-ion concentrationPoly vinyl alcohol(PVA)Unstimulated saliva
주제분류치의학

초록

이 연구의 목적은 인체 안정성이 입증된 고분자제제인 폴리비닐알코올(PVA, Poly vinyl alcohol)로 얇은 박막을 제조하고NaF을 첨가하여 불소를 함유한 고분자 접착 테잎(NaF-PVA)을 개발하여 피실험자의 구강 내에 도포 후 잔류하는 불소의농도를 측정하고자 하는 것이다. 불소바니쉬(Cavityshiled™, 0.25 ml, Group 1)와 불소를 함유한 고분자 접착 테잎(NaFPVA,Trial product, 1 ㎠ × 12개, Group 2)을 각각 10명씩 치과대학 남학생의 치아(상악 12개, 순면)에 도포 후, 30분, 1시간, 2시간, 3시간, 4시간, 24시간, 48시간, 72시간 후 비자극성 전타액내 불소농도를 불소이온전극을 이용하여 측정하였으며 다음과 같은 결과를 얻었다. 1. 도포 후 30분과 1시간에서는 1군이 2군보다 높은 타액 내 불소농도를 보였으나 유의한 차이는 없었다(p>0.05). 2. 도포 후 2시간, 3시간, 4시간에서 2군이 1군보다 유의하게 큰 값을 보였다(p<0.05). 3. 도포 후 24시간 이후부터는 군간 통계적으로 유의한 차이를 보이지 않았다(p>0.05).

Abstract

The purpose of this study is to investigate the residual fluoride concentration of polymer adhesive tape in oral cavity which is made by spraying NaF on PVA base and to compare with Fluoride varnish(Cavityshiled™). Experimental groups were divided into two according to application methods; Group 1(NaF-PVA tape) and Group 2(Cavityshiled™). Topical fluoride was applied to 20 healthy adults aged from 25 to 30. Fluoride concentration in unstimulated whole saliva was measured by fluoride-sensitive electrode for 72 hours. 1. Until 72 hours after application in every group, significantly higher fluoride concentration was shown in saliva than baseline value(p<0.05). 2. At 2, 3 and 4 hours after application, Group 2 revealed significantly higher fluoride concentration than Group 1(p<0.05). 3. At 24, 48 and 72 hours after application, there was no significance(p>0.05). Although the residual fluoride concentration of saliva and the amount of fluoride of NaF-PVA tape are lower than those of Cavityshield™, NaF-PVA tape is considered to be more effective since it showed almost the same result as CavityshieldTM. Therefore, NaF-PVA tape is expected to be a great fluoride application material.

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