Antibacterial Properties of Pit and Fissure Sealant Containing S-PRG filler on Streptococcus mutans
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초록
The purpose of this study was to evaluate the antibacterial properties of a sealant containing S-PRG filler compared to those of two contemporary commercial sealants to determine the inhibition of bacterial growth in broth culture and biofilm formation using the CDC Biofilm Reactor. The BeautiSealant containing S-PRG filler, the fluoride releasing ClinproTM sealant, which are known to have higher antibacterial effects, and the non-fluoride releasing ConciseTM sealant were selected for this study. A Streptococcus mutans culture in BHI broth without sealant served as a negative control in the planktonic growth inhibition test. As a result, bacterial growth was inhibited in all three sealant groups compared to that in the control. The ClinproTM sealant showed a significantly reduced number of CFUs compared to those of the BeautiSealant and ConciseTM sealants. However, no significant difference was detected between the BeautiSealant and ConciseTM sealants. The ClinproTM sealant significantly decreased biofilm formation compared to that by the BeautiSealant and ConciseTM sealants. No significant difference was observed between the BeautiSealant and ConciseTM sealants. In conclusion, the sealant containing S-PRG filler had a less potent anti-bacterial property and increased biofilm formation capacity compared to those of the fluoride releasing ClinproTM sealant.
Abstract
The purpose of this study was to evaluate the antibacterial properties of a sealant containing S-PRG filler compared to those of two contemporary commercial sealants to determine the inhibition of bacterial growth in broth culture and biofilm formation using the CDC Biofilm Reactor. The BeautiSealant containing S-PRG filler, the fluoride releasing ClinproTM sealant, which are known to have higher antibacterial effects, and the non-fluoride releasing ConciseTM sealant were selected for this study. A Streptococcus mutans culture in BHI broth without sealant served as a negative control in the planktonic growth inhibition test. As a result, bacterial growth was inhibited in all three sealant groups compared to that in the control. The ClinproTM sealant showed a significantly reduced number of CFUs compared to those of the BeautiSealant and ConciseTM sealants. However, no significant difference was detected between the BeautiSealant and ConciseTM sealants. The ClinproTM sealant significantly decreased biofilm formation compared to that by the BeautiSealant and ConciseTM sealants. No significant difference was observed between the BeautiSealant and ConciseTM sealants. In conclusion, the sealant containing S-PRG filler had a less potent anti-bacterial property and increased biofilm formation capacity compared to those of the fluoride releasing ClinproTM sealant.
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