CCTA를 이용한 관상동맥 협착과 석회화의 상관관계 분석
Correlation Analysis Between Stenosis and Calcification of Coronary Artery with Using CCTA
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본 연구는 관상동맥질환의 위험인자 중 성별, 연령별 협착률과 혈관 협착과 석회화와의 상관관계를 분석하기 위해 조사대상병원에서 조사 기간 동안 CCTA를 시행한 대상자 586명의 관상동맥의 협착률과 석회화의 유무를 조사하였다. 전체 대상자 중 협착이 있는 사람은 299명으로 이 중 남성 166명(28%), 여성 133명(23%)이었다. 50~70대가 협착이 있는 자의 246명(82.6%)으로 대부분을 차지하였다. 1개의 혈관이상에서 협착률이 50%가 넘는 협착이 있는 자는 299명 중 남성은 60대에서 43명(33.9%), 여성은 70대에서 39명(37.5%)으로 나타났다. Vessel score가 2점 이상 되는 경우가 70% 이상 협착이 있는 자 139명 중에 70명(50.1%)이었고 남성은 60대가 32명(39.5%), 여성은 70대가 27명(46.6%)으로 나타났다. 특징적인 것은 70대에서 Vessel score가 3점이 되는 경우가 14명으로 다른 연령대보다 2~5배까지 많은 결과를 볼 수 있었다. LAD가 77.6%, LCX가 47.5%, RCA가 60.5%의 협착 빈도를 나타내었고 삼중혈관병변(Triple vessel disease)은 남성이 15명(36.6%), 여성이 13명(56.5%)으로 남녀 모두 70대에서 가장 높은 빈도를 나타내었다. 협착이 있는 그룹에서는 196명(33.4%)이 석회화가 있었고, 관상동맥 협착이 없는 그룹에서는 40명(6.8%)만이 석회화가 있었다. 이것은 관상동맥의 협착에 석회화가 절대적인 영향을 미친다고는 볼 수 없지만, 상당히 연관성이 있다고 할 수 있겠다.
Abstract
We surveyed 586 patients who had been examined CCTA. Out of those patients, 299 (52%) has stenosis of coronary arteries; 166 males (28%) and 133 females (23%). Among them 246 stenosis patients (82.6%) are in 50's to 70's. The number of patients with 50% or more stenosis in more than 1 coronary artery is 299 including 43 males (33.9%) in their 60's and 39 females (37.5%) in their 70's. When a vessel score is higher than 2 points, 70 patients (50.1%) among 139 have 70% or more stenosis; 32 males (39.5%) in their 60's and 27 females (46.6%) in their 70's. It is noted that 14 patients in their 70's show more cases compared to other ages up to 2 or even 5 times when a vessel score is 3 points. LAD shows 77.6% of stenosis, LCX 47.5% and RCA 60.5%. Frequency of a triple vessel disease is high for patients in their 70's; 15 males (36.6%) and 13 females (56.5%) for both. 196 people (33.4%) in the group with stenosis have calcification, while only 40 (6.8%) in the group without stenosis have it. It means that calcification has a significant, if not absolute, correlation with stenosis of coronary arteries.
참고문헌 (20)
- 통계청, "사회통계국 인구동향과 : 2008년 사망원인통계 결과", ~ (2009)
- Murphy SL. Deaths, "final data for 1998", Natl Vital Stat Rep, 48, pp.1~105 (2000)
- Adler Y, "Spiral computed tomography evidence of close correlation between coronary and thoracic aorta calcifications", Atherosclerosis, 176, pp.133~138 (2004)
- Dougherty G, "Quantitative assessment of abdominal aortic atherosclerosis observed in CT scans", Comput Med Imaging Graph, 21, pp.185~193 (1997)
- Falk E, "Coronary plaque disruption", Circulation, 92, pp.657~671 (1995)
- Stary HC, "Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults", Arteriosclerosis, (suppl 9), pp.119~132 (1989)
- Achenbach S, "Detection of calcified and noncalcified coronary atherosclerotic plaque by contrast-enhanced, submillimeter multidetector spiral computed tomography : a segment-based comparison with intravascular ultrasound", Circulation, 109, pp.14~17 (2004)
- Leber A, "Accuracy of multidetector spiral computed tomography in identifying and differentiating the composition of coronary atherosclerotic plaques : a comparative study with intracoronary ultrasound", J Am Coll Cardiol, 43, pp.1241~1247 (2004)
- Myerburg RJ, "Frequency of sudden cardiac death and profiles of risk", Am J Cardiol, 80, pp.10F~19F (1997)
- Song MH, "Multidetector computed tomography versus coronary angiogram in evaluation of coronary artery bypass grafts", Ann Thorac Surg, 79, pp.585~588 (2005)
- Schlosser T, "Noninvasive visualization of coronary artery bypass grafts using 16-detector row computed tomography", J Am Coll Cardiol, 44, pp.1224~1229 (2004)
- Martuscelli E, "Evaluation of venous and arterial conduit patency by 16-slice spiral computed tomography", Circulation, 110, pp.3234~3238 (2004)
- Georgiou D, "Screening patients with chest pain in the emergency department using electron beam tomography: a follow-up study", J Am CollCardiol, 38, pp.105~110 (2001)
- Lamont DH, "Coronary calcium scanning adds incremental value to patients with positive stress tests", Am Heart J, 143, pp.861~867 (2002)
- Schroeder S, "Noninvasive evaluation of the prevalence of noncalcified atherosclerotic plaques by multi-slice detector computed tomography: results of a pilot study", Int JCardiol, 92, pp.161~165 (2003)
- Naghavi M, "From vulnerable plaque to vulnerable patient : a call for new definitions and risk assessment strategies : part II", Circulation, 108, pp.1772~1778 (2003)
- Enbergs A, "Failure to confirm ferritin and caerulolasmin as risk factors for the angiographic extent of coronary arteriosclerosis", Coro Artery Dis, 9, pp.119~124 (1998)
- O'Rourke RA, "American College of Cardiology", American Heart Association expert consensus document on electron-beam computed tomography for the diagnosis and prognosis of coronary artery disease, 2000, pp.36, 326~340
- Konieczynska M, "Use of coronary calcium score in the assessment of atherosclerotic lesions in coronary arteries", Kardiol Pol, 64, pp.1073~1079 (2006)
- Marwick TH, "Screening for coronary artery disease", Med Clin North Am, 83, pp.1375~1402 (1999)
