임신 중 갑상선 기능이상의 선별검사 및 관리
Screening and Management of Thyroid Dysfunction During Pregnancy
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Thyroid hormone is known to play a crucial role in implantation and embryonic development, as well as in the development of the nervous and musculoskeletal systems of fetus. In particular, thyroid dysfunction is associated with various pregnancy-related complications such as miscarriage, preterm birth, fetal growth restriction, and preeclampsia. Previous studies have primarily focus on the adverse effects of hypothyroidism on fetal neurodevelopment. However, the physiological and metabolic alterations occurring during pregnancy in thyroid physiology make it difficult to diagnose thyroid dysfunction. Therefore, obstetricians should have a comprehensive understanding of physiological changes of the thyroid and be familiar with the latest guidelines regarding the complications and management of thyroid dysfunction during pregnancy.
Abstract
Thyroid hormone is known to play a crucial role in implantation and embryonic development, as well as in the development of the nervous and musculoskeletal systems of fetus. In particular, thyroid dysfunction is associated with various pregnancy-related complications such as miscarriage, preterm birth, fetal growth restriction, and preeclampsia. Previous studies have primarily focus on the adverse effects of hypothyroidism on fetal neurodevelopment. However, the physiological and metabolic alterations occurring during pregnancy in thyroid physiology make it difficult to diagnose thyroid dysfunction. Therefore, obstetricians should have a comprehensive understanding of physiological changes of the thyroid and be familiar with the latest guidelines regarding the complications and management of thyroid dysfunction during pregnancy.
참고문헌 (27)
- Abalovich M, "Management of thyroid dysfunction during pregnancy and postpartum : an Endocrine Society Clinical Practice Guideline", J Clin Endocrinol Metab, 92(8 Suppl), pp.S1~47 (2007)
- Ain KB, "Reduced clearance rate of thyroxinebinding globulin(TBG)with increased sialylation : a mechanism for estrogen-induced elevation of serum TBG concentration", J Clin Endocrinol Metab, 65, pp.689~696 (1987)
- Alexander EK, "2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum", Thyroid, 27, pp.315~389 (2017)
- American College of Obstetricians and Gynecologists, "Thyroid disease in pregnancy: ACOG practice bulletin summary, number 223", Obstet Gynecol, 135, pp.1496~1499 (2020)
- Andersen SL, "Severity of birth defects after propylthiouracil exposure in early pregnancy", Thyroid, 24, pp.1533~1540 (2014)
- Baskin HJ, "American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism", Endocr Pract, 8, pp.457~469 (2002)
- Casey BM, "Subclinical hypothyroidism and pregnancy outcomes", Obstet Gynecol, 105, pp.239~245 (2005)
- Casey BM, "Treatment of subclinical hypothyroidism or hypothyroxinemia in pregnancy", N Engl J Med, 376, pp.815~825 (2017)
- Chen S, "Preconception TSH and pregnancy outcomes : a population-based cohort study in 184 611 women", Clin Endocrinol, 86, pp.816~824 (2017)
- Cleary-Goldman J, "Maternal thyroid hypofunction and pregnancy outcome", Obstet Gynecol, 112, pp.85~92 (2008)
- Clementi M, "Methimazole embryopathy : delineation of the phenotype", Am J Med Genet, 83, pp.43~46 (1999)
- Davis LE, "Thyrotoxicosis complicating pregnancy", Am J Obstet Gynecol, 160, pp.63~70 (1989)
- Gharib H, "Subclinical hypothyroidism during pregnancy : position statement from the American Association of Clinical Endocrinologists", Endocr Pract, 5, pp.367~368 (1999)
- Glinoer D, "Regulation of maternal thyroid during pregnancy", J Clin Endocrinol Metab, 71, pp.276~287 (1990)
- Haddow JE, "Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child", N Engl J Med, 341, pp.549~555 (1999)
- Hales C, "Controlled antenatal thyroid screening II : effect of treating maternal suboptimal thyroid function on child behavior", J Clin Endocrinol Metab, 105, pp.dgz098~ (2020)
- Hye Jeong Kim, "Reference intervals of thyroid hormones during pregnancy in Korea, an iodine-replete area", The Korean Journal of Internal Medicine, 33(3), pp.552~560 (2018), 대한내과학회[DOI]
- "Thyroid regulation and dysfunction in the pregnant patient, Endotext" (2000)[URL]
- Lazarus JH, "Antenatal thyroid screening and childhood cognitive function", N Engl J Med, 366, pp.493~501 (2012)
- Millar LK, "Low birth weight and preeclampsia in pregnancies complicated by hyperthyroidism", Obstet Gynecol, 84, pp.946~949 (1994)
- Moleti M, "Hyperthyroidism in the pregnant woman : Maternal and fetal aspects", J Clin Transl Endocrinol, 16, pp.100190~ (2019)
- 문희원, "Establishment of Trimester-Specific Reference Intervals for Thyroid Hormones in Korean Pregnant Women", Annals of Laboratory Medicine, 35(2), pp.198~204 (2015), 대한진단검사의학회
- Negro R, "Thyroid disease in pregnancy", Best Pract Res Clin Endocrinol Metab, 25, pp.927~943 (2011)
- Pop VJ, "Maternal hypothyroxinaemia during early pregnancy and subsequent child development : a 3-year follow-up study", Clin Endocrinol(Oxf), 59, pp.282~288 (2003)
- Stagnaro-Green A, "Clinical review 152 : Postpartum thyroiditis", J Clin Endocrinol Metab, 87, pp.4042~4047 (2002)
- van den Boogaard E, "Significance of(sub)clinical thyroid dysfunction and thyroid autoimmunity before conception and in early pregnancy : a systematic review", Hum Reprod Update, 17, pp.605~619 (2011)
- Yoshihara A, "Treatment of graves' disease with antithyroid drugs in the first trimester of pregnancy and the prevalence of congenital malformation", J Clin Endocrinol Metab, 97, pp.2396~2403 (2012)