Association between Metabolic Syndrome and Lower Urinary Tract Symptoms, Prostate S pecific Antigen, a nd P rostate Volume: Single C enter Study
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The purpose of this study was to investigate the influence of metabolic syndrome (MS) on the lower urinary tract symptoms (LUTS), prostate specific antigen (PSA), and prostate volume in Korean men. We analyzed the data from 2654 men over the age of 40 who visited our health promotion center for regular health checkups. Of the total 2654 men, mean age, PSA level, International Prostate Symptom Score (IPSS), and prostate volume were 54.6 years, 1.21ng/ml, 6.2 points, and 27.8ml, respectively. All examinees were divided into MS group (46.5%, 1235 men) and non-MS group (53.5%, 1419). Age and prostate volume were significantly higher in the MS group. The patients were divided into three groups according to their ages: 40's, 50's, and over 60 years old. Prostate volume of the MS group in the younger age groups (40-49 years and 50-59 years) was significantly larger than that of the non-MS group. However, no difference was revealed in the age group of 60-69 years. No significant differences were found in the PSA level and LUTS between the MS and non-MS groups. In the multivariate regression analysis, central obesity was the strongest risk factor for the enlargement of prostate over 30ml among the metabolic components.
Abstract
The purpose of this study was to investigate the influence of metabolic syndrome (MS) on the lower urinary tract symptoms (LUTS), prostate specific antigen (PSA), and prostate volume in Korean men. We analyzed the data from 2654 men over the age of 40 who visited our health promotion center for regular health checkups. Of the total 2654 men, mean age, PSA level, International Prostate Symptom Score (IPSS), and prostate volume were 54.6 years, 1.21ng/ml, 6.2 points, and 27.8ml, respectively. All examinees were divided into MS group (46.5%, 1235 men) and non-MS group (53.5%, 1419). Age and prostate volume were significantly higher in the MS group. The patients were divided into three groups according to their ages: 40's, 50's, and over 60 years old. Prostate volume of the MS group in the younger age groups (40-49 years and 50-59 years) was significantly larger than that of the non-MS group. However, no difference was revealed in the age group of 60-69 years. No significant differences were found in the PSA level and LUTS between the MS and non-MS groups. In the multivariate regression analysis, central obesity was the strongest risk factor for the enlargement of prostate over 30ml among the metabolic components.
참고문헌 (21)
- 김연민, "경직장초음파를 이용한 전립선 볼륨측정 시의 위치 연구: 전립선모형 제작과 실험", 방사선기술과학, 38(4), pp.437~442 (2015), 대한방사선과학회[DOI]
- 김미영, "혈청 전립선특이항원과 경직장초음파로 측정된 전립선 용적과의 상관관계", 방사선기술과학, 33(3), pp.239~243 (2010), 대한방사선과학회
- Park HS, "Prevalence of obesity and metabolic syndrome in Korean adults", Obes Rev, 9, pp.104~107 (2008)
- Reilly MP, "The metabolic syndrome: more than the sum of its parts?", Circulation, 108, pp.1546~1551 (2003)[DOI]
- Isomaa B, "Cardiovascular morbidity and mortality associated with the metabolic syndrome", Diabetes Care, 24, pp.683~689 (2001)[DOI]
- Gao Y, "Are metabolic syndrome and its components associated with lower urinary tract symptoms? Results from a Chinese male population survey", Urology, 79, pp.194~201 (2012)[DOI]
- Lee RK, "Central obesity as measured by waist circumference is predictive of severity of lower urinary tract symptoms", BJU Int, 110, pp.540~545 (2012)[DOI]
- Hammarsten J, "Hyperinsulinaemia as a risk factor for developing benign prostatic hyperplasia", Eur Urol, 39, pp.151~158 (2001)[DOI]
- Hammarsten J, "Components of the metabolic syndrome-risk factors for the development of benign prostatic hyperplasia", Prostate Cancer Prostatic Dis, 1, pp.157~162 (1998)[DOI]
- Ozden C, "The correlation between metabolic syndrome and prostatic growth in patients with benign prostatic hyperplasia", Eur Urol, 51, pp.199~203 (2007)[DOI]
- Parsons JK, "Obesity and benign prostatic hyperplasia: clinical connections, emerging etiological paradigms and future directions", J Urol, 182, pp.S27~S31 (2009)[DOI]
- 김재헌, "대사증후군과 관련된 남성 배뇨장애", Investigative and Clinical Urology, 47(3), pp.257~262 (2006), 대한비뇨의학회
- 권남성, "대사증후군의 존재와 전립선비대증의 상관관계: 건강검진자들을 대상으로 한 Hospital-Based Study", Investigative and Clinical Urology, 48(10), pp.1016~1021 (2007), 대한비뇨의학회
- 홍근식, "Correlation between Metabolic Syndrome and Lower Urinary Tract Symptoms of Males and Females in the Aspect of Gender-Specific Medicine: A Single Institutional Study", Investigative and Clinical Urology, 51(9), pp.631~635 (2010), 대한비뇨의학회
- 정지훈, "Association of Metabolic Syndrome and Benign Prostate Enlargement in Young Korean Males", Investigative and Clinical Urology, 52(11), pp.757~762 (2011), 대한비뇨의학회
- 박정선, "전립선비대증이 있는 환자에서 대사증후군의 의미", Investigative and Clinical Urology, 48(7), pp.696~700 (2007), 대한비뇨의학회
- 구교철, "전립선 건강검진을 받은 60세 이상의 남성에서 대사증후군과 전립선용적의 연관성", Investigative and Clinical Urology, 49(9), pp.813~817 (2008), 대한비뇨의학회
- Park HK, "Relationship between lower urinary tract symptoms and metabolic syndrome in a community-based elderly population", Urology, 72, pp.556~560 (2008)[DOI]
- "Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report", Circulation, 106, pp.3143~3421 (2002)[DOI]
- Lee SH, "Survey on benign prostatic hyperplasia distribution and treatment patterns for men with lower urinary tract symptoms visiting urologists at general hospitals in Korea: a prospective, noncontrolled, observational cohort study", Urology, 79, pp.1379~1384 (2012)[DOI]
- Lee S, "Central obesity as a risk factor for prostatic hyperplasia", Obesity (Silver Spring), 14, pp.172~179 (2006)[DOI]