사상체질과 경동맥 내중막 두께의 상관성 연구
Relationship between Intima Media Thickness of Common Carotid Artery and Sasang Constitution
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
1. Objectives This study is to investigate the relationship between Intima Media Thickness(IMT) of common carotid artery and Sasang Constitution. 2. Methods 839 persons, over 40 years old, participated in community-based cohort of Korea Genome and Epiedemiology Study (KOGES)in Wonju City and Pyeongchang City of South Korea from June 2006 to February 2008. The diagnosis of Common carotid Intima Media Thickness was evaluated by B Mode ultrasonography, cardiovascular risk factors were checked using questionnaire and blood samples. Constitution was verified by a Sasang constitution specialist according to the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Multiple regression analysis and logistic regression analysis were performed with SPSS. 3. Results There were significantly high values in waist circumference, fasting blood sugar, systolic blood pressure, diastolic blood pressure,triglyceride, HOMA-IR and hsCRP in Taeeumin and low in HDL-cholesterol and adiponectin in Taeeumin. There were significantly high value in Common Carotid Intima Media Thickness in Taeeumin. Age was the significant cardiovascular risk factor irrespective of Sasang constitution in all participants. There was a positive correlation between smoking and Soyangin in all participants and men. There were positive correlations between LDL-cholesterol, BMI and Taeeumin in all participants and men. There were positive correlations between hsCRP and Soeumin in all participants and men. There was significantly high odds ratio of Taeeumin over Soeumin in common carotid Intima Media Thickness. 4. Conclusions Regimens on cardiovascular diseases should be considered according to Sasang constitution. There are more sensitive risk factor in each constitution; smoking in Soyangin, LDL-cholesterol and BMI in Taeeumin, hsCRP in Soeumin.
Abstract
1. Objectives This study is to investigate the relationship between Intima Media Thickness(IMT) of common carotid artery and Sasang Constitution. 2. Methods 839 persons, over 40 years old, participated in community-based cohort of Korea Genome and Epiedemiology Study (KOGES)in Wonju City and Pyeongchang City of South Korea from June 2006 to February 2008. The diagnosis of Common carotid Intima Media Thickness was evaluated by B Mode ultrasonography, cardiovascular risk factors were checked using questionnaire and blood samples. Constitution was verified by a Sasang constitution specialist according to the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Multiple regression analysis and logistic regression analysis were performed with SPSS. 3. Results There were significantly high values in waist circumference, fasting blood sugar, systolic blood pressure, diastolic blood pressure,triglyceride, HOMA-IR and hsCRP in Taeeumin and low in HDL-cholesterol and adiponectin in Taeeumin. There were significantly high value in Common Carotid Intima Media Thickness in Taeeumin. Age was the significant cardiovascular risk factor irrespective of Sasang constitution in all participants. There was a positive correlation between smoking and Soyangin in all participants and men. There were positive correlations between LDL-cholesterol, BMI and Taeeumin in all participants and men. There were positive correlations between hsCRP and Soeumin in all participants and men. There was significantly high odds ratio of Taeeumin over Soeumin in common carotid Intima Media Thickness. 4. Conclusions Regimens on cardiovascular diseases should be considered according to Sasang constitution. There are more sensitive risk factor in each constitution; smoking in Soyangin, LDL-cholesterol and BMI in Taeeumin, hsCRP in Soeumin.
참고문헌 (33)
- "사망원인통계" (2009)[URL]
- 보건복지부, "심·뇌혈관질환 고위험군 등록관리 시범사업 고혈압·당뇨병 등록관리 운영지침", ~ (2007)
- Grobbee DE, "Carotid intima-media thickness as a indicator of generalized atherosclerosis", J Intern Med, 236, pp.567~573 (1994)
- Bruke GL, "Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults", Stroke, 26, pp.386~391 (1995)
- Ebrahim S, "Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women", Stroke, 30, pp.841~850 (1999)
- O'Leary DH, "Carotid artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults", N Engl J Med, 340, pp.14~22 (1999)
- Chambless LE, "Carotid wall thickness is predictive of incident clinical stroke", Am J Epidemiol, 151, pp.478~487 (2000)
- Baldassarre D, "Carotid artery intima-media thickness measured by ultrasonography in normal clinical practice correlates well with atherosclerosis risk factors", Stroke, 31, pp.2426~2430 (2000)
- Matsumoto K, "Correlation between common carotid arterial wall thickness and ischemic stroke in patients with type 2 diabetes mellitu", Metabolism, 51, pp.244~247 (2002)
- 황민우, "腦卒中 患者의 四象體質別 特性에 關한 硏究", 사상체질의학회지, 17(1), pp.103~119 (2005), 사상체질의학회
- 이태규, "사상체질에 따른 대사증후군의 유병률과 위험인자에 대한 연구", 대한한의학회지, 27(2), pp.14~22 (2006), 대한한의학회
- The Prevalence and Risk Factors of the Metabolic Syndrome according to Sasang Constitution in Middle Aged Persons, "Hahm TI", Bachelor's Paper of Kyunghee University, ~ (2007)
- 양상묵, "원주 코호트에서 四象體質에 따른 代謝症候群 有病率과 관련요인", 사상체질의학회지, 21(1), pp.186~196 (2009), 사상체질의학회
- Kim SJ(Jin XJ), "A Study on the Intima-media Thickness of Common Carotid Artery of Taeumin Over 40 Years Old", 박사, pp.2008
- 이준희, "사상체질과 대사증후군 및 경동맥 내중막두께와의 상관관계 연구", 사상체질의학회지, 19(1), pp.142~159 (2007), 사상체질의학회
- Pavel Poredoš, "Intima-media thickness: indicator of cardiovascular risk and measure of the extent of atherosclerosis", Vascular Medicine, 9, pp.46~54 (2004)
- Cho YL, "Reference values of carotid artery intima-media thickness and association with atherosclerotic risk factors in healthy subjects in Korea", Korean J Med, 64(3), pp.275-283~ (2003)
- G Howard, "Carotid artery intiaml medial thickness dirstibution in general populations as evaluated by B-mode ultrasound", Stroke, 24, pp.1297~1304 (1993)
- Lee SK, "Ther Carotid Artery Intima-Media Thickness Measurement with B-Mode Ultrasonography in Adult Volunteers", Korean Circ J, 29(11), pp.1201~1211 (1999)
- 배장호, "대한민국 정상인과 위험인자군의 경동맥 내중막 두께:다기관 역학연구", Korean Circulation Journal, 35(7), pp.513~524 (2005), 대한심장학회
- 현대우, "초음파와 새로운 소프트웨어를 이용한 경동맥 내막,중막, 내중막 두께측정", Korean Circulation Journal, 35(8), pp.625~632 (2005), 대한심장학회
- Lloyd E, "Carotid wall thickness is predictive of incidence clinical stroke; The Artherosclerosis risk in Community(ARIC) study", Am J Epidemiol, 151(5), pp.478~487 (2000)
- Konstaninos NV, "Common carotid artery intima-media thickness in patients with brain infarction and intracerebral haemorrhage", Cerebrovasc Dis, 17, pp.280~286 (2004)
- Tsivgoulis G, "Stamatelopoulous K et al. Common carotid artery intima-media thickness and risk of stroke recurrence", Am Heart Association, 37(7), pp.1913~1916 (2006)
- Alain Simon, "Intima-media thickness: a new tool for diagnosis and treatment of cardiovascular risk", Journal of Hypertension, 20, pp.159~169 (2002)
- Pierre-Jean Touboul, "Common Carotid Artery Intima-Media Thickness: The Cardiovascular Risk Factor Multiple Evaluation in Latin America(CARMELA) Study Results", Cerebrovascular Diseases, 31, pp.43~50 (2011)
- Philippa J. Delahoy, "The Relationship Between Reduction in Low-Density Lipoprotein Cholesterol by Statins and Reduction in Risk of Cardiovascular Outcomes: An Updated Meta-Analysis", Clinical Therapeutics, 31(2), pp.236~244 (2009)
- Elena Burillo, "High-density lipoprotein cholesterol increase and non-cardiovascular mortality: a metaanalysis", Heart, 96, pp.1345~1351 (2010)
- Ryuichi Kawamoto, "Low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is the best surrogate marker for insulin resistance in non-obese Japanese adults", Lipids in Health and Disease, 9, pp.138~138 (2010)
- Maia-Fernandes T, "Cardiovascular actions of adiponectin: pathophysiologic implications", 27(11), pp.1431~1449 (2008)
- Nienke J. Wijnstok, "Inflammation Markers are Associated with Cardiovascular Diseases Risk in Adolescents: The Young Hearts Project 2000", J Adolesc Health, 47(4), pp.346~351 (2000)
- N.A. Zakai, "Inflammation and hemostasis biomarkers and cardiovascular risk in the elderly: the Cardiovascular Health Study", Journal of Thrombosis and Haemostasis, 5, pp.1128~1135 (2007)
- Syed Shahid Habib, "CRP Levels are Higher in Patients with ST Elevation Than Non-ST Elevation Acute Coronary Syndrome", Arq Bras Cardiol, 96(1), pp.13~17 (2011)
