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원주농촌코호트에서 사상체질별 심혈관위험인자와 골다공증의 관계

Relationship between Osteoporosis and Cardiovascular Risk Factors according to Sasang Constitution in Rural Wonju Cohort

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Objectives The purpose of this study was to investigate the relationship between osteoporosis and cardiovascular risk factors according to Sasang constitution. Methods A total of 1773 participants, over 40 years old, were examined as part of a community-based cohort in Wonju city in Gangwon province of South Korea, from June 2006 to August 2009. We measured bone mineral density by Achilles ultrasonometer, serum levels of lipids, fasting blood sugar, insulin and other cardiovascular risk factors like blood pressure and waist circumference. Constitution was verified by a Sasang constitution specialist using the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Results The prevalence rate was 11.2% in total participants, and 10.6% in Soyangin, 10.4% in Taeeumin and 13.9% in Soeumin. In general characteristics, educational and economic property and exercise were concerned with osteoporosis. Systolic blood pressure, pulse rate and total cholesterol were significantly high in osteoporosis group. Age and menopause were the key risk factors for osteoporosis. There was a significantly high prevalence in Soeumin for osteoporosis in men alone. Low physical activity was a major risk factor for osteoporosis. Waist circumference and hip circumference had significantly high odds ratio and weight had significantly low odds ratio. By Sasang constitution, Soyangin has the negative correlation with free fatty acid, Taeeumin has the negative correlation with waist circumference, pulse rate, systolic blood pressure, total cholesterol and low density lipoprotein and Soeumin has the positive correlation with body fat amount. Conclusions Regimens on osteoporosis should be considered according to Sasang constitution. Cardiovascular diseases should be considered according to Sasang constitution. Soeumin should be cautious of osteoporosis and gain weights and reasonable amount of fat food. Soyangin had better do exercise lower body and eat little food containing triglyceride. Taeeumin had better lose weights and eat little cholesterol food.

Abstract

Objectives The purpose of this study was to investigate the relationship between osteoporosis and cardiovascular risk factors according to Sasang constitution. Methods A total of 1773 participants, over 40 years old, were examined as part of a community-based cohort in Wonju city in Gangwon province of South Korea, from June 2006 to August 2009. We measured bone mineral density by Achilles ultrasonometer, serum levels of lipids, fasting blood sugar, insulin and other cardiovascular risk factors like blood pressure and waist circumference. Constitution was verified by a Sasang constitution specialist using the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Results The prevalence rate was 11.2% in total participants, and 10.6% in Soyangin, 10.4% in Taeeumin and 13.9% in Soeumin. In general characteristics, educational and economic property and exercise were concerned with osteoporosis. Systolic blood pressure, pulse rate and total cholesterol were significantly high in osteoporosis group. Age and menopause were the key risk factors for osteoporosis. There was a significantly high prevalence in Soeumin for osteoporosis in men alone. Low physical activity was a major risk factor for osteoporosis. Waist circumference and hip circumference had significantly high odds ratio and weight had significantly low odds ratio. By Sasang constitution, Soyangin has the negative correlation with free fatty acid, Taeeumin has the negative correlation with waist circumference, pulse rate, systolic blood pressure, total cholesterol and low density lipoprotein and Soeumin has the positive correlation with body fat amount. Conclusions Regimens on osteoporosis should be considered according to Sasang constitution. Cardiovascular diseases should be considered according to Sasang constitution. Soeumin should be cautious of osteoporosis and gain weights and reasonable amount of fat food. Soyangin had better do exercise lower body and eat little food containing triglyceride. Taeeumin had better lose weights and eat little cholesterol food.

참고문헌 (32)

  1. The Third Korean National Health and Nutrition Examination Survey(KNHANES III): summary-2010, "Korean Centers for Disease Control and Prevention", Korean Centers for Disease Control and Prevention, ~ (2010)
  2. Boukhris R, "Calcification of the aorta and osteoporosis", JAMA, 219, pp.1307~1311 (1972)
  3. Magnus JH, "Relationship between bone mineral density and myocardial infarction in US adults", Osteoporos Int, 16(12), pp.2053~2062 (2005)
  4. Tanko LB, "Low bone mineral density in the hip as a marker of advanced atherosclerosis in elderly women", Calcif Tissue Int, 73(1), pp.15~20 (2003)
  5. Farhat GN, "Volumetric and areal bone mineral density measures are associated with cardiovascular disease in older men and women: the health, aging, and body composition study", Calcif Tissue Int, 79(2), pp.102~111 (2006)
  6. Dominguez LJ, "Physiology of the aging bone and mechanisms of action of bisphosphonates", Biogerontology, 12, pp.397~408 (2011)
  7. Klift M, "Laet CEDH. Bone mineral density and the risk of peripheral arterial disease: the Rotterdam Study", Calcif Tissue Int, 70(6), pp.443~449 (2002)
  8. Yamaguchi T, "Plasma lipids and osteoporosis in postmenopausal women", Endocr J, 49(2), pp.211~217 (2002)
  9. Kammerer CM, "Bone mineral density, carotid artery intimal medial thickness, and the vitamin D receptor BsmI polymorphism in Mexican American women", Calcif Tissue Int, 75(4), pp.292~298 (2004)
  10. Barengolts EI, "Chomka EV. Osteoporosis and coronary atherosclerosis in asymptomatic postmenopausal women", Calcif Tissue Int, 62(3), pp.209~213 (1998)
  11. Hak AE, "Progression of aortic calcification is associated with metacarpal bone loss during menopause : a population-based longitudinal study", Arterioscler Thromb Vasc Biol, 20, pp.1926~1931 (2000)
  12. Vogt MT, "Bone mineral density and aortic calcification: the Study of Osteoporotic Fractures", J Am Geriatr Soc, 45(2), pp.140~145 (1997)
  13. Collins TC, "Peripheral arterial disease is associated with higher rates of hip bone loss and increased fracture risk in older men", Circulation, 119(17), pp.2305~2312 (2009)
  14. Lee JM, "Dongeuisusebowonsasangchobongwon", pp.226~250 (2003), Jipmoondang
  15. 안윤진, "반정량식품섭취빈도조사지의 타당성 검증 및 보정 - 지역사회 유전체 코호트 참여자를 대상으로 -", 대한지역사회영양학회지, 9(2), pp.173~182 (2004), 대한지역사회영양학회
  16. Kannel WB, "A general cardiovascular risk profile: the Framingham study", Am J Cardiol, 38(1), pp.46~51 (1976)
  17. Yusuf S, "Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study):case-control study", Lancet, 364(9438), pp.937~952 (2004)
  18. Mosca L, "Cardiovascular disease in women: a statement for healthcare professionals from the American Heart Association", Circulation, 96(7), pp.2468~2482 (1997)
  19. Ezzati M, "Role of smoking in global and regional cardiovascular mortality", Circulation, 112(4), pp.489~497 (2005)
  20. Gotoh M, "High blood pressure, bone-mineral loss and insulin resistance in women", Hypertens Res, 28(7), pp.565~570 (2005)
  21. Mussolino ME, "Bone mineral density and hypertension prevalence in postmenopausal women; Results from the Third National Health and Nutrition Examination Survey", Ann Epidemiol, 16(5), pp.395~399 (2006)
  22. Kim SR, "Relationship between Osteoporosis and Cardiovascular Risk Factors in Premenopausal Women", 석사, pp.2010
  23. Buizert PJ, "Lipid levels: a link between cardiovascular disease and osteoporosis?", J Bone Miner Res, 24(6), pp.1103~1109 (2009)
  24. Yamaguchi T, "Plasma lipids and osteoporosis in postmenopausal women", Endocr J, 49(2), pp.211~217 (2002)
  25. Samelson EJ, "Long-term effects of serum cholesterol on bone mineral density in women and men: The Framingham Osteoporosis Study", Bone, 34, pp.557~561 (2004)
  26. Adami S, "Relationship between lipids and bone mass in 2 cohorts of healthy women and men", Calcif Tissue Int, 74, pp.136~142 (2004)
  27. Brownbill RA, "Lipid profile and bone paradox: higher serum lipids are associated with higher bone mineral density in postmenopausal women", J Womens Health (Larchmt), 15(3), pp.261~270 (2006)
  28. Tanko LB, "Does serum cholesterol contribute to verterbral bone loss in postmenopausal women?", Bone, 32, pp.8~14 (2003)
  29. 한범희, "폐경 후 여성에서 골밀도와 심혈관위험인자의 관련성에 대한 연구", 한국콘텐츠학회 논문지, 9(10), pp.176~185 (2009), 한국콘텐츠학회
  30. Cui LH, "Association between bone mineral densities and serum lipid profiles of pre- and post-menopausal rural women in South Korea", Osteoporos Int., 16(12), pp.1975~1981 (2005)
  31. Lee JM, "Dongeuisusebowon", pp.12~13 (1988), Daesung Publishing Co
  32. Jankowska EA, "Are general obesity and visceral adiposity in men linked to reduced bone mineral content resulting from normal ageing? A population-based study", Andrologia, 33(6), pp.384~389 (2001)

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