태음조위탕의 적용이 태음인 비만여대생의 신체조성, 혈청지질농도 및 혈중 항산화 효소에 미치는 효과
Effect of Taeeumjoweetang on the Body Composition, Serum Lipid Level and Antioxidant Enzyme Activity of Obese Female College Students
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참고문헌
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초록
1. Objectives Though the eating habits have improved and the living method has become convenient according to the economic growth thanks to the modern industrialization, because of the lack of exercise, obesity, wrong eating habits and stress etc, various symptoms of disease of adults are on the rise. This is the phenomenon that happens as the eating life has become life in the West along with the inundation of the western culture in our society. In this perspective, there has been many various clinical research that's been proceeded so far about the physical constitution and obesity, but there has been little research on the objective analysis of the clinical research about the alimentotherapy using taeeumjoweetang. 2. Methods In this research we have checked the weights, fat rates, fat weight, abdominal fat rate, blood pressure, and BMI over the objects of the women that were diagnosed as lunisolar system as their physical constitution, and assessed the paramecium lipid, in-blood antioxidation enzyme and the damage of oxidization in the urine by physical constitution-specific of the body shapes that were determined by BMI. The statistical analysis of the current research was processed by using of SPSS 17.0 program. We have figure out statistical amounts such as the arithmetic average, average deviation rate and percentage number. Fro the verification of he significancy of each elements, we have used the paired t-test,ANOVA, Chi-square test at the level of p<0.05. 3. Results and Conclusions Their characteristics are age 21.20±1.35, height 160.30±6.11㎝, weight 64.66±8.72㎏, fat rates are 35.97±4.87%, fat amount 23.40±5.48,abdominal fat rate 0.823±0.03, BMI 25.12±2.79㎏/㎡, and systolic blood pressure 111.60±10.28㎜Hg and diastolic blood pressure 68.60±7.43㎜Hg and we have let them take the medicine twice a day for 8 weeks. The clinical result for the Cholesterol, Triglyceride, HDL-cholesterol, LDL-cholesterol, SGOT, SGPT, of the object people was that for the function of the liver, the result of the SGOT and SGPT test was 17.16±3.05, 15.00±2.99IU/L, which was a decrease, and had statistical meaning, but for the SGOT, though the figure reduced to 11.92±4.61, 10.80±3.07, it had no statistical meaning. For the whole cholesterol level, the figure reduced to 169.00±19.95, 160.08±22.52 mg/dL and had statistical significance(p<0.05). Neuter fat number, Triglyceride has slightly increased to 67.52±36.32, 68.08±47.33 mg/dL but did not have any statistical meaning. The antioxdant enzyme marker standard marker, SOD has increased to 2.52±0.73, 2.86±0.60U/ml, and had statistical significance(p<0.01). Catalase also increased by 0.63±0.18,1.07±0.25mmol/ml and had statistical meaning(p<0.01). GPx also increased to 204.76±32.64 nmol/ml and had statistical meaning(p<0.01). But, for the Total antioxidant, though it has raised to 1.51±0.26, 1.57±0.17nmol/㎕, it did not have any statistical meaning. MDA of oxidative stress marker has decreased to 1.70±0.68㎍/ml, 1.21±0.50㎍/m and had statistical significance(p<0.01). 8-OHdG also decreased 3.35±0.95ng/ml,2.21±0.50ng/ml and had statistical meaning(p<0.01). In this research, we have analyzed the various markers relating to BFM and changes in oxidative enzyme in blood by takingtaeeumjoweetang. Taeeumjoweetang has the positive effect on inbody antioxidant system and reducing the content of cholesterol, which is proven to help losing weight and improving hyperlipidemia statistically. With this research, we hope to improve the lifestyle of those who are either obese or need to manage their dietary habits, and also to become the touchstone of integrating Oriental Medicine with the science of food & nutrition.
Abstract
1. Objectives Though the eating habits have improved and the living method has become convenient according to the economic growth thanks to the modern industrialization, because of the lack of exercise, obesity, wrong eating habits and stress etc, various symptoms of disease of adults are on the rise. This is the phenomenon that happens as the eating life has become life in the West along with the inundation of the western culture in our society. In this perspective, there has been many various clinical research that's been proceeded so far about the physical constitution and obesity, but there has been little research on the objective analysis of the clinical research about the alimentotherapy using taeeumjoweetang. 2. Methods In this research we have checked the weights, fat rates, fat weight, abdominal fat rate, blood pressure, and BMI over the objects of the women that were diagnosed as lunisolar system as their physical constitution, and assessed the paramecium lipid, in-blood antioxidation enzyme and the damage of oxidization in the urine by physical constitution-specific of the body shapes that were determined by BMI. The statistical analysis of the current research was processed by using of SPSS 17.0 program. We have figure out statistical amounts such as the arithmetic average, average deviation rate and percentage number. Fro the verification of he significancy of each elements, we have used the paired t-test,ANOVA, Chi-square test at the level of p<0.05. 3. Results and Conclusions Their characteristics are age 21.20±1.35, height 160.30±6.11㎝, weight 64.66±8.72㎏, fat rates are 35.97±4.87%, fat amount 23.40±5.48,abdominal fat rate 0.823±0.03, BMI 25.12±2.79㎏/㎡, and systolic blood pressure 111.60±10.28㎜Hg and diastolic blood pressure 68.60±7.43㎜Hg and we have let them take the medicine twice a day for 8 weeks. The clinical result for the Cholesterol, Triglyceride, HDL-cholesterol, LDL-cholesterol, SGOT, SGPT, of the object people was that for the function of the liver, the result of the SGOT and SGPT test was 17.16±3.05, 15.00±2.99IU/L, which was a decrease, and had statistical meaning, but for the SGOT, though the figure reduced to 11.92±4.61, 10.80±3.07, it had no statistical meaning. For the whole cholesterol level, the figure reduced to 169.00±19.95, 160.08±22.52 mg/dL and had statistical significance(p<0.05). Neuter fat number, Triglyceride has slightly increased to 67.52±36.32, 68.08±47.33 mg/dL but did not have any statistical meaning. The antioxdant enzyme marker standard marker, SOD has increased to 2.52±0.73, 2.86±0.60U/ml, and had statistical significance(p<0.01). Catalase also increased by 0.63±0.18,1.07±0.25mmol/ml and had statistical meaning(p<0.01). GPx also increased to 204.76±32.64 nmol/ml and had statistical meaning(p<0.01). But, for the Total antioxidant, though it has raised to 1.51±0.26, 1.57±0.17nmol/㎕, it did not have any statistical meaning. MDA of oxidative stress marker has decreased to 1.70±0.68㎍/ml, 1.21±0.50㎍/m and had statistical significance(p<0.01). 8-OHdG also decreased 3.35±0.95ng/ml,2.21±0.50ng/ml and had statistical meaning(p<0.01). In this research, we have analyzed the various markers relating to BFM and changes in oxidative enzyme in blood by takingtaeeumjoweetang. Taeeumjoweetang has the positive effect on inbody antioxidant system and reducing the content of cholesterol, which is proven to help losing weight and improving hyperlipidemia statistically. With this research, we hope to improve the lifestyle of those who are either obese or need to manage their dietary habits, and also to become the touchstone of integrating Oriental Medicine with the science of food & nutrition.
참고문헌 (35)
- Skilton MR, "Endothelial dysfunction and arterial abnormalities in childhood obesity", Int J OBes, 30, pp.1041~1091 (2006)
- 박정아, "대구지역 주부들의 비만정도에 따른 식행동 특성과 영양섭취 실태 평가", 대한지역사회영양학회지, 10(5), pp.623~632 (2005), 대한지역사회영양학회
- Byun JY, "Effects of acupuncture at Chok-samni on pain in rats", The Journal of Korean acupuncture and moxibustion society, 15(2), pp.287~300 (1998)
- 임재연, "서울지역 중학생의 BMI에 따른 영양소 섭취실태와 체력에 관한 연구", 대한지역사회영양학회지, 10(1), pp.22~35 (2005), 대한지역사회영양학회
- Hwang YY, "A study on obese female college students weight control experiences", Korean J Women Health Nurs, 10(4), pp.291~300 (2004)
- Kim EY, "A clinical study on the sasang constitution and obesity", J Sasang Constitut Med, 16(1), pp.100~101 (2004)
- 유종향, "사상체질별 임상지표와 건강상태의 연관성 연구 - 여성을 중심으로 -", 사상체질의학회지, 21(3), pp.107~121 (2009), 사상체질의학회
- 이화섭, "拱辰黑元丹이 初期老化 흰 쥐의 抗老化 및 抗酸化에 미치는 영향", 사상체질의학회지, 19(3), pp.242~256 (2007), 사상체질의학회
- Kim KJ, "Experimental study on constitutional composition of serum lipid", J Sasang Constitut Med, 5(1), pp.263~270 (1993)
- . Han JS, "Anorexigenoic effect of Taeyeumjowui-tang in obese Zucker rat", The Korean Academy of Oriental Rehabilitation Medicine, 15(4), pp.131~145 (2005)
- 이시우, "사상체질 임상 연구 현황에 대한 조사연구 -사상체질의학회지를 중심으로-", 사상체질의학회지, 20(2), pp.21~29 (2008), 사상체질의학회
- 이주용, "升陽益氣湯 전탕액이 노화쥐의 비장, 췌장, 위장 세포의 항산화능에 미치는 영향", 사상체질의학회지, 22(2), pp.82~92 (2010), 사상체질의학회
- Kim GY, "A study on the changes of blood constituent in male students TAE-EUM-IN", J Sasang Constitut Med, 3(1), pp.215~222 (1991)
- Higdon, "Obesity and oxidative stress: Adirect link to CVD Arterioscler", Thromb. Vasc. Biol, 23, pp.365~367 (2003)
- Kim SH, "A study on the standardization of QSCC Ⅱ(Qestionnaire of Sasang Constitution Classification) Ⅱ", Kyung Hee University, ~ (2003)
- Margit Bernroitner, "Christian Obinger Occurrence, phylogeny, structure, and function of Catalases and peroxidases in cyanobacteria", Journal of Experimental Botany, 60(2), pp.423~440 (2009)
- Johnson LH, "A spectrophtometric method for determination of Catalase activity in small tissue samples", Analytical Biochemistry, 174, pp.331~336 (1988)
- Parkash S, "2-mercaptoethylamine as a masking agent for the complexometric determination of palladium(II) in catalaysts, alloys and complexes", J Chil. Chem Soc, 53, pp.1611~1614 (2008)
- McCord, "Mechanisms of disease oxygen derived free radicals in postischemic tissue injury", The New England J. Medicine, 312(3), pp.159~163 (1985)
- Ministry of Health and Welfare, "Korea National Health and Nutrition Examination Survey", ~ (2008)
- 김미옥, "여대생들의 체중에 대한 인식과 신체 부위별 만족도", 한국식품영양학회지, 22(2), pp.205~214 (2009), 한국식품영양학회
- Anderson JW, "Oatbran cereal lowers serum total and LDL-cholesterol in hypercholesterolemic men", Am. J. Clin, Nutr, 52, pp.445~451 (1986)
- Park KS, "Physicochemical and texture of bread added paecilomyces japonica according to storage period", J. East Asian Soc. Dietary Life, 11(6), pp.485~497 (2001)
- Song IB, "Sasang Constitution Medititution and Constitutional Foods", Korean J. dietary culture, 3(4) (1988)
- 강인정, "체질보감" (1998), 서울: 도서출판 넥서스
- Jeon EY, "The effects of sasang constitutional diet for essential hypertension on blood pressure, fat and serum lipid", Journal of Korean Acadmic Nurse, 32(5), pp.673~683 (2002)
- E. Braunwald, "Harrson's principles of Internal Medicinek, 15th edition" (2003), 서울:도서출판 MIP
- 고성경, "BMI와 %Fat에 의한 비만도 평가가 고지혈중 진단에 미치는 영향", 운동과학, 14(1), pp.21~30 (2005), 한국운동생리학회
- Lee GJ, "Effects of Taeyeumjoweetang on the obesity of mouse and induced adipocyte 3T3- L1", Won Kwang University, ~ (1996)
- 김효정, "太陰調胃湯을 복용한 太陰人ㆍ少陰人ㆍ少陽人의 반응에 대한 임상보고", 동의생리병리학회지, 22(6), pp.1600~1605 (2008), 대한동의병리학회
- Flohe L, "Convenient as says for superoxide dismutase", pp.287~293 (1992), CRC Handbook of free radicals and antioxidants in Biomedicine
- Beckman KB, "The Free radical Theory of aging matures", Physiol. Rev, 78, pp.547~571 (1998)
- Paglia ED, "Studies on the quantitative and qualitative characterization of erythrocytes glutathione peroxidase", Journal of Laboratory Clin Med, 70, pp.158~169 (1979)
- Buge JA, "Microsomal lipid peroxidation. In : Fleicher S, Packer L eds", Methods in enzymelogy, 52, pp.302~309 (1978)
- Orville A, "Platelet glutathione peroxidase activity as an index of selenium status in rats", J Nutr, 13, pp.55~63 (1983)
