본문 바로가기
KERD
논문KCI 등재

구강조직 미세환경 특이적 구강청량제 개발의 필요성

The necessity of new conceptual mouthwash development depending on oral tissue-specific micro-environments

0

조회

0

다운로드

2

인용

0

참고문헌

키워드

초록

전세계적으로 위생 및 개인 외모 유지에 대한 의식이 높아지면서 구강 위생 시장이 확대되고 있다. 특히구강청량제는 휴대하기 간편하고 입안을 헹궈내는 방식으로 사용이 가능하기 때문에 사용하는 소비자가 늘어나고 있다. 이에 따라 관련 제품의 시장 규모도 지속적으로 성장하고 있으며 프리미엄 콘셉트 및 고기능성구강용품의 개발에 대한 소비자들의 관심이 더욱 높아지고 있다. 이러한 시장환경을 선도할 수 있는 신개념의 구강위생제품의 개발 및 상용화를 위해서는, 고도화된 과학기술에 의해 축적된 연구결과를 이용한 제품의 개발 및 생산이 절실히 요구되고 있다. 특히 외래 다빈도 상병 진료 1위를 차지하는 치주질환은 진행정도와 구강환경에 따른 예방과 치료가 가능하여, 기존 구강청량제의 한계에 대해 분석하고 기능적으로 월등하고 시너지를 기대할 수 있는 기능성 성분들을 탑재하여 새로운 제품을 생산할 수 있는 기반의 확립이 필요하다.

Abstract

Recently, oral care market is mainly driven by increasing people’s awareness about oral hygiene. Mouthwashes are becoming increasingly popular among oral care products. Consumers in oral care market desire for new or more functionally improved mouthwashes. To develop and commercialize new conceptual and functional mouthwash products that are tissue- and condition-specific, including gingivitis, periodontitis, and implantitis, it is necessary to understand and consider the relevant cellular and histological research results findings accumulated by advanced research in science and technology. In particular, periodontal disease, which is the most common oral disease, can be prevented and treated depending on the progress and oral tissue specific micro-environment. Therefore, it is necessary to analyze the limitations of existing mouthwashes and establish a foundation for development new products with remarkable ingredients.

참고문헌 (31)

  1. Sudip Bhattacharya, "“Mask Mouth Syndrome“-An emerging oral health threat during the COVID-19 pandemic", Journal of Family Medicine and Primary Care, 11(8), pp.4869~ (2022), Medknow[DOI]
  2. Philipp Kanzow, "COVID-19 Pandemic: Effect of Different Face Masks on Self-Perceived Dry Mouth and Halitosis", International Journal of Environmental Research and Public Health, 18(17), pp.9180~ (2021), MDPI AG[DOI]
  3. Lubna Al‐Nasser, "Prevention and management of periodontal diseases and dental caries in the older adults", Periodontology 2000, 84(1), pp.69~83 (2020), Wiley[DOI]
  4. G. Baima, "Periodontitis and Accelerated Biological Aging: A Geroscience Approach", Journal of Dental Research, 101(2), pp.125~132 (2021), SAGE Publications[DOI]
  5. Frauke Müller, "Periodontitis and peri‐implantitis in elderly people experiencing institutional and hospital confinement", Periodontology 2000, 90(1), pp.138~145 (2022), Wiley[DOI]
  6. Janet A. Yellowitz, "Elder's Oral Health Crisis", Journal of Evidence Based Dental Practice, 14, pp.191~200 (2014), Elsevier BV[DOI]
  7. Leonardo Marchini, "Coronavirus disease 2019 and dental care for older adults", The Journal of the American Dental Association, 151(12), pp.881~884 (2020), Elsevier BV[DOI]
  8. 박지혜, "코로나19 상황이 대학생들의 구강건강행태 및 구강증상에 미치는 영향", 대한구강보건학회지, 45(4), pp.192~197 (2021), 대한예방치과·구강보건학회[DOI]
  9. Xiang Qi, "Oral health conditions and COVID-19: A systematic review and meta-analysis of the current evidence", Aging and Health Research, 2(1), pp.100064~ (2022), Elsevier BV[DOI]
  10. Aleksandra Wdowiak-Szymanik, "Pandemic COVID-19 Influence on Adult’s Oral Hygiene, Dietary Habits and Caries Disease—Literature Review", International Journal of Environmental Research and Public Health, 19(19), pp.12744~ (2022), MDPI AG[DOI]
  11. 이병진, "구강양치액의 최신 경향", 대한치과의사협회지, 55(2), pp.180~188 (2017), 대한치과의사협회[DOI]
  12. Agrawal Amit, "Exploring the Factors Influencing the Choice of Oral Care Products: A Review on Personalized Approach", International Journal of Oral and Dental Health, 6(2) (2020), ClinMed International Library[DOI]
  13. Sam R. Aspinall, "Oral care product formulations, properties and challenges", Colloids and Surfaces B: Biointerfaces, 200, pp.111567~ (2021), Elsevier BV[DOI]
  14. Haerian-Ardakani A, "Comparison of Antimicrobial Effects of Three Different Mouthwashes", Iran J Public Health, 44(7), pp.997~1003 (2015)
  15. Katebi K, "Effect of Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Xerostomia:A Systematic Review and Meta-Analysis", J Dent(Shiraz), 24(1), pp.76~83 (2023)[DOI]
  16. Dominik Radzki, "A Fresh Look at Mouthwashes—What Is Inside and What Is It For?", International Journal of Environmental Research and Public Health, 19(7), pp.3926~ (2022), MDPI AG[DOI]
  17. "Mouthwash market"[URL]
  18. L Hu, "Stem cell‐based tooth and periodontal regeneration", Oral Diseases, 24(5), pp.696~705 (2017), Wiley[DOI]
  19. Jan Krivanek, "Heterogeneity and Developmental Connections between Cell Types Inhabiting Teeth", Frontiers in Physiology, 8 (2017), Frontiers Media SA[DOI]
  20. Frank A. Scannapieco, "The prevention of periodontal disease—An overview", Periodontology 2000, 84(1), pp.9~13 (2020), Wiley[DOI]
  21. Masahide Takedachi, "Evaluation of periodontitis-related tooth loss according to the new 2018 classification of periodontitis", Scientific Reports, 12(1) (2022), Springer Science and Business Media LLC[DOI]
  22. Frank Schwarz, "Surgical therapy of peri‐implantitis", Periodontology 2000, 88(1), pp.145~181 (2022), Wiley[DOI]
  23. "Hira opendata"[URL]
  24. "Hira opendata"[URL]
  25. Danielle Clark, "In the dental implant era, why do we still bother saving teeth?", Dental Traumatology, 35(6), pp.368~375 (2019), Wiley[DOI]
  26. Filippo Graziani, "Nonsurgical and surgical treatment of periodontitis: how many options for one disease?", Periodontology 2000, 75(1), pp.152~188 (2017), Wiley[DOI]
  27. Syed Akhtar H. Bokhari, "Periodontitis in coronary heart disease patients: strong association between bleeding on probing and systemic biomarkers", Journal of Clinical Periodontology, 41(11), pp.1048~1054 (2014), Wiley[DOI]
  28. Gil L, "Periodontal Disease in Pregnancy : The Influence of General Factors and Inflammatory Mediators", Oral Health Prev Dent, 17(1), pp.69~73 (2019)[DOI]
  29. Mireya Martínez-García, "Periodontal Inflammation and Systemic Diseases: An Overview", Frontiers in Physiology, 12 (2021), Frontiers Media SA[DOI]
  30. 박재욱, "줄기세포 기반의 치주조직재생", 대한구강해부학회지, 35(1), pp.51~76 (2014), 대한구강해부학회[DOI]
  31. 황금빛, "Differential Localization of ODAM in Periodontitis with Similar Clinical Severities", 대한구강해부학회지, 42(1), pp.37~46 (2021), 대한구강해부학회[DOI]

관련 논문AI추천

이 간행물의 다른 논문 (11건)