갑상선질환의 세침흡인도말검사에서 질환별 특징적인 소견에 관한 연구 : 유두상 암종과 다른 질환과의 비교를 중심으로

Abstract

This study observed appearance existence and non-existence of nuclear groove, intranuclear pseudoinclusion, papillae, psammoma body, lymphocyte, multinucleated giant histiocyte and follicular structure that is a feature of cytologic change in FNAC of several thyroid nodules, and analyzed cytologic features of other thyroid diseases in comparison with papillary carcinoma of the thyroid. The FNAC total in 103cases(Benign lesion 40cases, Neoplasm 22cases and Malignant lesion 41cases) through a Hematoxylin-eosin and Papanicolaou stain from cytomorphologic change by nodular lesions was observed and compared. The results were as follows. A papillary structure(88%) and psammoma body(24%) were observed in papillary carcinoma, and intranuclear pseudoinclusion was observed in papillary carcinoma(94%) and medullary carcinoma(29%), and nuclear grooves were observed in all nodular lesions(table 5). Appearance of lymphocytes was observed in all nodular lesions except hurthle cell tumor but appearance frequency was highly remarkable in grave’s disease(100%), hashimoto’s thyroiditis(100%) and subacute thyroiditis( 100%). A multinucleated giant histiocyte was observed in subacute thyroiditis(l00%), papillarycarcinoma(82%), adenomatous goiter(33%) and hashimoto’s thyroiditis(26% ) but expressed a high appearance frequency in subacute thyroiditis(Table 5). A follicular structure was observed in all nodular lesions except hurthle cell tumor and sub acute thyroiditis but expressed a high appearance frequency in follicular neoplasm(100%) and grave’s disease(100%) (Table 5). Conclusively, a papillary structure and psammoma body of cytologic features change showed papillary carcinoma in FNAC but it is considered when diagnosing papillary carcinoma because nuclear grooves and intranuclear pseudoinclusion can be observed in other nodular lesions.