Type II 당뇨병 환자의 혈당 조절 안자로 1,5Anhydroglucitol과 HbAIC의 비교
Comparison of 1,5Anhydroglucitol and HbAIC as Clinical Marker of Glycemic Control in Type II Diabetes Mellitus Patients
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Abstract
1,5Anhydroglucitol (1,5AG) is one of the major polyols in human body. It provides useful information on current glycemic control and is superior to HbA1C. To evaluate the use of plasma 1,5Anhydroglucitol (1,5AG) levels in screening for type II diabetes mellitus, the relationship between the plasma concentration of 1,5AG and HbA1C was examined in 127 patients with type II diabetes mellitus Patients. Subjects were separated into five groups based on diabetes control and complication trial (DCCT) criteria: normal group (NG), normal DM patient (ND), near normal glycemia (NN), good control (GC), action suggested (AS) groups. Fasting plasma glucose (F=70.99, P> 0.0001), 1,5AG (F=28.2, P> 0.0001) and HbA1C (F=15.14, P> 0.000)1) concentrations showed significant differences between each groups. These fmdings suggest that the plasma 1,5AG concentration can be a useful index of type II diabetes mellitus patients.