객담 세포학의 평가에서 액체 기반 세포학과 Conventional Smear 의 비교
Comparison of Liquid-based Cytology and Conventional Smear in the Evaluation of Sputum Cytology
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초록
The cytology of sputum specimens, at a medical facility in Korea, is using the liquid-based cytology and conventional smear method. It confirms the diagnosis using conventional smear methods and the liquid-based cytology. In addition, the diagnosis uses two kinds of each method, compares the suitability, sensitivity and specificity for each test and tries to understand the efficient method needed. It divided sputum specimens in half and liquid-based cytology. A conventional smear method was conducted and the Papanicolaou's staining was conducted using Autostainer. Diagnosed each slide of staining produced smear slides specimens by using an optical microscope. The result of the liquid-based cytology and conventional smear method was that the liquid-based cytology was of a higher-grade than the conventional smear method. It was 36.8%, and 62.8% in the same condition. But only one case was of a lower grade. Liquid-based cytology showed 86.2% of adequacy, 31.0% of sensitivity and 97.5% of specificity. The conventional smear method showed 54.4% of adequacy, 19.6% of sensitivity and 100% of specificity. If it was conducted with two methods at the same time, the results would be similar to the liquid-based cytology. In conclusion, liquid-based cytology has a more superior adequacy and sensitivity than the conventional smear method. The combination of the two methods is similar to the result of only conducting a liquid-based cytology. Conducting a liquid-based cytology rather than the combination of the two ways of sputum cytoscopy, is to be considered as an efficient method to achieve diagnostic accuracy, reduce labor of clinical technologist and pathologist, and to reduce the expense of patients.
Abstract
The cytology of sputum specimens, at a medical facility in Korea, is using the liquid-based cytology and conventional smear method. It confirms the diagnosis using conventional smear methods and the liquid-based cytology. In addition, the diagnosis uses two kinds of each method, compares the suitability, sensitivity and specificity for each test and tries to understand the efficient method needed. It divided sputum specimens in half and liquid-based cytology. A conventional smear method was conducted and the Papanicolaou's staining was conducted using Autostainer. Diagnosed each slide of staining produced smear slides specimens by using an optical microscope. The result of the liquid-based cytology and conventional smear method was that the liquid-based cytology was of a higher-grade than the conventional smear method. It was 36.8%, and 62.8% in the same condition. But only one case was of a lower grade. Liquid-based cytology showed 86.2% of adequacy, 31.0% of sensitivity and 97.5% of specificity. The conventional smear method showed 54.4% of adequacy, 19.6% of sensitivity and 100% of specificity. If it was conducted with two methods at the same time, the results would be similar to the liquid-based cytology. In conclusion, liquid-based cytology has a more superior adequacy and sensitivity than the conventional smear method. The combination of the two methods is similar to the result of only conducting a liquid-based cytology. Conducting a liquid-based cytology rather than the combination of the two ways of sputum cytoscopy, is to be considered as an efficient method to achieve diagnostic accuracy, reduce labor of clinical technologist and pathologist, and to reduce the expense of patients.
참고문헌 (13)
- Choi YD, "Effectiveness of sputum cytology using ThinPrepⓇ method for evaluation of lung cancer", Diagn Cytopathol, 36, pp.167~171 (2008)
- Elsheikh TM, "Comparison of ThinPrep and cytospin preparations in the evalution of exfoliative cytology specimens", Cancer (Cancer Cytopathol), 108, pp.144~149 (2006)
- 고재수, "자궁경부, 체액 및 소변의 탈락 세포진 검사에서 CellPrep？ 액상세포검사의 세포학적 평가 -ThinPrep？과 비교분석-", 대한세포병리학회지, 18(1), pp.29~35 (2007), 대한세포병리학회
- 구지혜, "체액 세포검사에서 고식적 세포도말검사와 CellprepPlus 액상세포검사의 세포학적 평가 비교", Journal of Pathology and Translational Medicine, 43(5), pp.448~452 (2009), 대한병리학회
- 구지혜, "초음파 유도 갑상샘 세침흡인세포검사에서 CellprepPlus® 액상세포검사: 고식적 도말검사와 CellprepPlus® 액상세포검사와의 비교", Journal of Pathology and Translational Medicine, 45(2), pp.182~187 (2011), 대한병리학회
- Leung CS, "Comparision of ThinPrep and conventional preparatios: nongynecologic cytology evalution", Diagn Cytopathol, 16, pp.368~371 (1997)
- Motherby H, "Semiautomated monolayer preparation of bronchial secretions using AutoCyte PREP", Acta Cytol, 43, pp.47~57 (1999)
- Rana DN, "A comparative study: conventional preparation and ThinPrep 2000 in respiratory cytology", Cytopathology, 12, pp.390~398 (2001)
- 손승명, "Evaluation of Urine Cytology in Urothelial Carcinoma Patients: A Comparison of CellprepPlus® Liquid-Based Cytology and Conventional Smear", Journal of Pathology and Translational Medicine, 46(1), pp.68~74 (2012), 대한병리학회
- 임현이, "폐암 환자의 기관지 세척 검체에 대한 고식적 세포도말검사, 세포 블록, 액상세포검사의 비교", Journal of Pathology and Translational Medicine, 45(3), pp.296~302 (2011), 대한병리학회
- 유창영, "뇌척수액에서 백혈병세포의 세포소견; 액상세포검사법과 고식적인 세포원심분리법과의 비교", Journal of Pathology and Translational Medicine, 43(2), pp.164~170 (2009), 대한병리학회
- 조은윤, "폐암 진단방법으로서 객담검사의 유용성", 대한세포병리학회지, 15(2), pp.75~80 (2004), 대한세포병리학회
- 국가암등록사업연례보고서, "보건복지부", 23~ (2011)