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사료를 통한 Benzo(a)pyrene 노출에 따른 조피볼락, Sebastes schlegeli의 생화학 및 조직병리학적 변화

Biochemical and Histopathological Changes of Rockfish, Sebastes schlegeli by Dietary Benzo(a)pyrene

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Abstract

-superoxide dismutase (SOD) activity and histopathological change of hepatic tissue forrockfish, Sebastes schlegeli after feeding sub-chronic dietary Benzo(a)pyrene (BaP) inthe concentration of 0 (control), 0.5, 1.0, 1.5, 2.0 mg kg-1 dry food of diet for 30 days.In 2.0 mg kg-1 dry food group, the significant increase of LPO was observed in allperiod, and SOD activity was incresed at 30 days significantly in the same concen-tration. In the histological investigation of liver, there was the swelling of hepatic cellsat 10 days over the 1.0 mg kg-1 dry food concentration. At 30 days Periodic acid -Schiff(PAS) positive granule was observed in the same group and at 20 days was observed in2.0 mg kg-1 dry food group. And there was necrosis of hepatic cell in some fish of 2.0mg kg-1 dry food group at 30 days.

참고문헌 (23)

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