한강 유역에서 분리한 Enterococcus 속 세균의 항생제 감수성
Antimicrobial Susceptibility of Enterococcus spp. Isolated from Han-river Area in Korea
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Abstract
From the 4 sampling stations located in the basin of the Han River, total 46 strains of Enterococcus spp. composed of 15 E. faecium strains, 26 E. casseliflavus strains, 1 E. faecalis strain and 4 E. hirae strains were isolated. Among the 46 strains, 45 strains exhibited streptomycin-resistance, while 21 and 19 stains were resistant against tetracycline and quinupristin/dalfopristin, respectively. As for gentamicin and vancomycin, 15 strains and 1 strain showed resistance against the respective antimicrobial agents. Among the 46 strains, 39 strains showed resistance against more than 2 antimicrobial agents, and 10 strains demonstrated resistance to more than 5 antimicrobial agents. Especially, the strain isolated from the station C at Anyangcheon, exhibited resistance against all the 8 kinds of the antimicrobial agents. As the sampling site approached to the lower stream of the Han-river, the antibiotic resistant strains and the multi-drug resistant strains were detected more frequently. The MIC values of the antibiotic resistant strains measured by the disc diffusion method disclosed that 16 strains possessed maximum MIC value of 4,096 μg mL-1 against streptomycin and 17 strains possessed maximum MIC value of 2,048 μg mL-1 against gentamicin. Meanwhile, 1 strain exhibited maximum MIC value of 512 μg mL-1 against vancomycin. As for quinupristin/dalfopristin and tetracycline, 2 and 33 strains showed maximum MIC value of 64 μg mL-1, respectively. Comparison of the MIC values of the strains of the this study with those of the strains of the other research groups isolated from the hospital drainage and also those from the live stock farm drainage indicated that the strains resistant against vancomycin and quinupristin/ dalfopristin may be originated from the livestock farm drainage.
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