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Postmortem Diagnosis of Diabetic Ketoacidosis: An Autopsy Case

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Diabetic ketoacidosis is an acute complication of type 1 diabetes mellitus, which is observed frequently in routine autopsies. However, there are limitations of postmortem diagnosis of diabetic ketoacidosis. Clinical diagnostic criteria of the disease are not applicable to postmortem diagnosis because of the postmortem changes of the body; hence, diagnostic morphological changes cannot be observed. We report the case of a 47-year-old man that was diagnosed with diabetic ketoacidosis via routine autopsy and laboratory tests without information regarding his medical history. Additionally, we present a brief literature review.

Abstract

Diabetic ketoacidosis is an acute complication of type 1 diabetes mellitus, which is observed frequently in routine autopsies. However, there are limitations of postmortem diagnosis of diabetic ketoacidosis. Clinical diagnostic criteria of the disease are not applicable to postmortem diagnosis because of the postmortem changes of the body; hence, diagnostic morphological changes cannot be observed. We report the case of a 47-year-old man that was diagnosed with diabetic ketoacidosis via routine autopsy and laboratory tests without information regarding his medical history. Additionally, we present a brief literature review.

참고문헌 (5)

  1. Braunwald E, "Harrison’s principles of internal medicine", pp.2116~2118 (2001), McGraw-Hill
  2. Maitra A, "Robbins and Cotran pathologic basis of disease", pp.1097~1064 (2009), Elsevier
  3. Palmiere C, "Postmortem chemistry update: part I", Int J Legal Med, 126, pp.187~198 (2012)
  4. Kanetake J, "The relationship of a high level of serum beta-hydroxybutyrate to cause of death", Leg Med (Tokyo), 7, pp.169~174 (2005)
  5. Kodikara S, "The role of the Armanni-Ebstein lesion, hepatic steatosis, biochemical analysis and second generation anti-psychotic drugs in fatal diabetic ketoacidosis", J Forensic Leg Med, 20, pp.108~111 (2013)

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