심장 내 치즈양 물질: 당뇨병케톤산증 환자에서 발생한고도의 고중성지질혈증 부검증례 보고
Cheese-like Material in the Heart: An Autopsy Case Report of Severe Hypertriglyceridemia in Diabetic Ketoacidosis Patient
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Here we report an autopsy case of diabetic ketoacidosis (DKA) with severe hypertriglyceridemia (12,900 ㎎/㎗). A 29-year-old woman with a history of type 1 diabetes was found dead at a motel. There was no injury on external inspection, but a lump of cheese-like material was noted in the heart at autopsy and peripheral blood plasma had a creamy appearance. After postmortem biochemical analysis, we made a diagnosis of DKA with severe hypertriglyceridemia and concluded that these unusual autopsy findings were caused by DKA and postmortem change. Uncontrolled diabetes often causes DKA and hypertriglyceridemia. To the best of our knowledge, this is the first report in Korea of DKA with severe hypertriglyceridemia diagnosed by autopsy.
Abstract
Here we report an autopsy case of diabetic ketoacidosis (DKA) with severe hypertriglyceridemia (12,900 ㎎/㎗). A 29-year-old woman with a history of type 1 diabetes was found dead at a motel. There was no injury on external inspection, but a lump of cheese-like material was noted in the heart at autopsy and peripheral blood plasma had a creamy appearance. After postmortem biochemical analysis, we made a diagnosis of DKA with severe hypertriglyceridemia and concluded that these unusual autopsy findings were caused by DKA and postmortem change. Uncontrolled diabetes often causes DKA and hypertriglyceridemia. To the best of our knowledge, this is the first report in Korea of DKA with severe hypertriglyceridemia diagnosed by autopsy.
참고문헌 (10)
- Fulop M, "Severe hypertriglyceridemia in diabetic ketosis", Am J Med Sci, 300, pp.361~365 (1990)
- Choi DS, "A case of severe hypertriglyceridemia with diabetic ketoacidosis", J Korean Diabetes Assoc, 23, pp.715~721 (1999)
- 한석재, "Severe Hypertriglyceridemia in Diabetic Ketoacidosis Accompanied by Acute Pancreatitis: Case Report", Journal of Korean Medical Science, 25(9), pp.1375~1378 (2010), 대한의학회
- 정현희, "Ketoacidosis with Hypertriglyceridemia-Induced Pancreatitis in a Patient with Gestational Diabetes: A Case Report", Endocrinology and Metabolism, 27(1), pp.89~92 (2012), 대한내분비학회
- Zilg B, "Postmortem identification of hyperglycemia", Forensic Sci Int, 185, pp.89~95 (2009)
- Boulagnon C, "Post-mortem biochemistry of vitreous humor and glucose metabolism: an update", Clin Chem Lab Med, 49, pp.1265~1270 (2011)
- Uemura K, "Biochemical blood markers and sampling sites in forensic autopsy", J Forensic Leg Med, 15, pp.312~317 (2008)
- 이영진, "혈장교환술로 고중성지방혈증에 의한 임신성췌장염 치료 1예", 대한수혈학회지, 22(1), pp.70~75 (2011), 대한수혈학회
- Williamson S, "Severe hyperlipidaemia complicating diabetic ketoacidosis", Arch Dis Child, 97, pp.735~ (2012)
- Kasper DL, "Harrison’s principles of internal medicine", pp.2286~2298 (2005), McGraw-Hill