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피클링솔트에 의한 아질산염중독: 4예 보고

Fatal Nitrite Intoxication by Pickling Salt: Four Autopsy Cases

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Pickling salt, also known as curing salt, is a mixture of sodium chloride and sodium nitrite, which is used for color agent and a means to facilitate food preservation. Recently, online purchase of pure sodium nitrite has been restricted, and pickling salts have been used as replacements in cases of suicidal nitrite intoxication. From November 2020 to December 2021, there were four autopsy cases of nitrite poisoning caused by pickling salt, and 10 autopsy cases of nitrite poisoning by pure sodium nitrite. Due to the low nitrite concentration in pickling salts, serum nitrite and nitrate concentration, and methemoglobin levels were relatively low in pickling salts cases. Especially, low methemoglobin levels may cause confusion in the postmortem diagnosis of fatal nitrite intoxication, so caution is required.

Abstract

Pickling salt, also known as curing salt, is a mixture of sodium chloride and sodium nitrite, which is used for color agent and a means to facilitate food preservation. Recently, online purchase of pure sodium nitrite has been restricted, and pickling salts have been used as replacements in cases of suicidal nitrite intoxication. From November 2020 to December 2021, there were four autopsy cases of nitrite poisoning caused by pickling salt, and 10 autopsy cases of nitrite poisoning by pure sodium nitrite. Due to the low nitrite concentration in pickling salts, serum nitrite and nitrate concentration, and methemoglobin levels were relatively low in pickling salts cases. Especially, low methemoglobin levels may cause confusion in the postmortem diagnosis of fatal nitrite intoxication, so caution is required.

참고문헌 (5)

  1. 박민지, "아질산염 중독으로 인한 사망: 14예 보고", 대한법의학회지, 44(2), pp.96~101 (2020), 대한법의학회[DOI]
  2. "Death of high school student after receiving flu vaccine caused by sodium nitrate poisoning, police say" (2020)[URL]
  3. Kim M, "Determination of nitrite and nitrate in postmortem whole blood samples of 10 sodium nitrite poisoning cases : the importance of nitrate in determining nitrite poisoning", Forensic Sci Int, 335, pp.111279~ (2022)
  4. Hwang C, "An autopsy case of sodium nitriteinduced methemoglobinemia with various post-mortem analyses", Forensic Sci Med Pathol, 17, pp.475~480 (2021)
  5. Katabami K, "Severe methemoglobinemia due to sodium nitrite poisoning", Case Rep Emerg Med, 2016, pp.9013816~ (2016)

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