고등학생 대상 맞춤의학 체험 프로그램 개발 및 적용
Development and Application of Personalized Medicine Experience Instruction Modulesfor High School Students
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초록
5 Instruction modules of personalized medicine experience program for high school students were developed and applied on school science programs. The program focused on gene analysis was composed of serial molecular biology experiments which are DNA extraction from oral cavity epidermal cells, duplication of target DNA by PCR, and Gel electrophoresis for confirmation of genomic DNA and ACE polymorphism respectively and a computer search activity for ACE using NCBI site. Program applied on 7 classes of 126 high school students and analyzed students′ responses with questionnaire. 88.9% Students accomplished total program successfully and they diagnosed the possibility of hereditary high blood pressure. Students’ most interesting activity is Agarose gel electrophoresis, Duplication of DNA by PCR, DNA extraction, and NCBI searching in order. Students’ worst difficulty is Loading DNA specimen on agarose gel, Making PCR specimen, Using micropipette, DNA extraction, and Making agarose gel orderly. 39.1% of newly learned science knowledge were from PCR activity among 4. They have positively experienced molecular biology experiments, future career, personalized medicine, bioinformatics and etc. From the results, developed program was helpful to experience personalized medicine for high school students.
Abstract
5 Instruction modules of personalized medicine experience program for high school students were developed and applied on school science programs. The program focused on gene analysis was composed of serial molecular biology experiments which are DNA extraction from oral cavity epidermal cells, duplication of target DNA by PCR, and Gel electrophoresis for confirmation of genomic DNA and ACE polymorphism respectively and a computer search activity for ACE using NCBI site. Program applied on 7 classes of 126 high school students and analyzed students′ responses with questionnaire. 88.9% Students accomplished total program successfully and they diagnosed the possibility of hereditary high blood pressure. Students’ most interesting activity is Agarose gel electrophoresis, Duplication of DNA by PCR, DNA extraction, and NCBI searching in order. Students’ worst difficulty is Loading DNA specimen on agarose gel, Making PCR specimen, Using micropipette, DNA extraction, and Making agarose gel orderly. 39.1% of newly learned science knowledge were from PCR activity among 4. They have positively experienced molecular biology experiments, future career, personalized medicine, bioinformatics and etc. From the results, developed program was helpful to experience personalized medicine for high school students.
참고문헌 (30)
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