함초 (Salicornia bigelovii) 추출물의 라디칼 소거능과Acetylcholinesterase 저해 효과
Radical scavenging and acetylcholinesterase inhibitory activities of various extracts from Salicornia bigelovii
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This study was to investigate the extraction yield, total polyphenolics and flavonoid contents, radical scavenging activity, and acetylcholinesterase inhibitory activity of various extracts from Salicornia bigelovii. The extraction yields of hot water, ethanol, acetone, ethylacetate, and hexane were 18.8%, 15.4%, 2.6%, 13.3%, and 3.2%, respectively. The total polyphenolics and flavonoid contents in hot water extract (HWE) and ethanol extract (EE) were significantly higher than in acetone (AE), ethylacetate (EAE), and hexane extracts (HE). The total polyphenol and flavonoid contents were highest in EE (0.89% and 0.39%), followed by HWE (0.76% and 0.25%), AE (0.45% and 0.18%), EAE (0.36% and 0.14%) and HE (0.28% and 0.11%). ABTS radical scavenging activities in 10mg/L of extracts were in the following order: EE (48.97%)> HWE (18.92%)> AE (14.32%)> EAE (12.50%)> HE (10.37%). In addition, the acetylcholinesterase inhibitory activity was observed in the same tendency as seen with the ABTS radical scavenging activity. These results suggest that the ethanol and hot water extracts from S. bigelovii may be used to develop various functional food and cosmetic products.
Abstract
This study was to investigate the extraction yield, total polyphenolics and flavonoid contents, radical scavenging activity, and acetylcholinesterase inhibitory activity of various extracts from Salicornia bigelovii. The extraction yields of hot water, ethanol, acetone, ethylacetate, and hexane were 18.8%, 15.4%, 2.6%, 13.3%, and 3.2%, respectively. The total polyphenolics and flavonoid contents in hot water extract (HWE) and ethanol extract (EE) were significantly higher than in acetone (AE), ethylacetate (EAE), and hexane extracts (HE). The total polyphenol and flavonoid contents were highest in EE (0.89% and 0.39%), followed by HWE (0.76% and 0.25%), AE (0.45% and 0.18%), EAE (0.36% and 0.14%) and HE (0.28% and 0.11%). ABTS radical scavenging activities in 10mg/L of extracts were in the following order: EE (48.97%)> HWE (18.92%)> AE (14.32%)> EAE (12.50%)> HE (10.37%). In addition, the acetylcholinesterase inhibitory activity was observed in the same tendency as seen with the ABTS radical scavenging activity. These results suggest that the ethanol and hot water extracts from S. bigelovii may be used to develop various functional food and cosmetic products.
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