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Optimal Condition for High Concentrations of Lignan Aglycon from Fermented Acanthopanacis Caulis Cortex(Acanthopanax sessiliflorus)

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The purpose of the study is to develop a new process to manufacture high content of lignan aglycon (syringaresinol) from Acanthopanacis Caulis Cortex (Acanthopanax sessiliflorus) extract. Saccharomyces cerevisiae liquid culture fermentation transformed glycoside component (eleutheroside E and E1) of Acanthopanacis Caulis Cortex into aglycon component (syringaresinol). The transformation process from lignan glycosides to lignan aglycon was monitored by HPLC to optimize the fermentation conditions. AS-48 (liquid cultured mixture by Saccharomyces cerevisiae for 48 hours at 28 ℃) had the highest content of syringaresinol (9.411%). However, other mixtures (AS-24, AS-72, AS-144, and AS-168) had less than 9.0% in the content of syringaresinol. However, unfermented Acanthopanacis Caulis Cortex (AS) did not contain syringaresinol.

Abstract

The purpose of the study is to develop a new process to manufacture high content of lignan aglycon (syringaresinol) from Acanthopanacis Caulis Cortex (Acanthopanax sessiliflorus) extract. Saccharomyces cerevisiae liquid culture fermentation transformed glycoside component (eleutheroside E and E1) of Acanthopanacis Caulis Cortex into aglycon component (syringaresinol). The transformation process from lignan glycosides to lignan aglycon was monitored by HPLC to optimize the fermentation conditions. AS-48 (liquid cultured mixture by Saccharomyces cerevisiae for 48 hours at 28 ℃) had the highest content of syringaresinol (9.411%). However, other mixtures (AS-24, AS-72, AS-144, and AS-168) had less than 9.0% in the content of syringaresinol. However, unfermented Acanthopanacis Caulis Cortex (AS) did not contain syringaresinol.

참고문헌 (32)

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