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시공간 재활훈련이 조현병 환자의 시공간 기능과 주의에 미치는 효과

The Effect of Visuospatial Rehabilitation on the Visuospatial Function and Attention in Patients with Schizophrenia

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참고문헌

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주제분류심리과학

초록

본 연구는 시공간 재활훈련이 조현병 환자들의 시공간 기능을 포함한 인지기능의 향상과 사회적 기능, 조현병 증상의 완화에 효과적인가를 알아보고자 하였다. 연구대상은 서울 소재 사회복귀시설에 거주하고 있는 조현병 환자 43명으로, 이들은 재활집단(n=14), 비교집단(n=14), 통제집단(n=15)으로 무선할당되었다. 재활집단은 주 3회 각 40분씩 6주에 걸쳐 총 18회기의 시공간 재활훈련을, 비교집단은 동일한 회기 동안 테트리스 게임을 실시하였고, 통제집단은 아무런 처지도 받지 않았다. 시공간 재활훈련 프로그램은 Bracy (1994)가 개발한 PSS CogReHab을 국내 상황에 맞게 수정하여 개발한 인지재활 프로그램을 사용하였다. 시공간 기능/시각기억, 주의, 언어기억, 작업기억, 집행기능을 평가하는 신경심리검사와 조현병 증상을 측정하는 Positive and Negative syndrome Scale (PANSS), 사회적 기능을 평가하는 한국판 정신사회적 기능-증상 평가척도(BASIS-32) 설문지를 재활훈련 전과 후에 실시하였다. 그 결과, 재활 후 실시한 신경심리검사에서 재활집단은 비교집단과 통제집단과 다르게 Rey 도형검사 모사단계, 숫자외우기 검사의 바로 따라외우기 조건, Stroop 검사의 단어-색채 조건의 수행이 유의하게 증가하였다. 그리고 재활집단에서 PANSS로 측정한 음성증상이 완화된 것이 관찰되었다. 이러한 결과는 시공간기능 재활이 조현병 환자의 시공간 기능 및 주의 기능 향상, 음성증상 완화에 효과적이라는 것을 의미하며, 조현병 환자의 치료에 시공간 기능을 포함하는 인지재활의 필요성을 시사한다.

Abstract

This study investigated the effect of visuospatial rehabilitation on the cognitive function in patients with schizophrenia. Fortythree patients with schizophrenia were randomly assigned into one of the three groups (rehabilitation, comparative, and control groups). The comprehensive neuropsychological tests including Rey-Osterreith Complex Figure Test (RCFT), Block Design, Puzzle, Korea-California Verbal Learning Test (K-CVLT), Stroop test, Digit Span, Spatial Span, and Wisconsin Card Sorting Test (WCST) were administered before and after rehabilitation for the three groups. In addition, schizophrenic symptoms and social function were measured by PANSS, and BASIS-32, respectively. Participants in the rehabilitation group received individual visuospatial rehabilitation three times a week for a 6 weeks durations, and the comparative group received the individual tetris game three times a week for a 6 weeks durations; the control group did not receive any treatment. The three groups did not differ on the performances of the neuropsychological tests, PANSS, and BASIS-32, which were administered before rehabilitation. However, the rehabilitation group showed significantly better performances on RCFT copy condition, Digit Span forward condition, color-word condition of the Stroop test, and PANSS negative symptom than the comparative and control groups after rehabilitation. These findings suggest that visuospatial rehabilitation is effective in improving visuospatial function, attention, and negative symptoms in patients with schizophrenia.

참고문헌 (95)

  1. Addington, J., "Neurocognitive and social functioning in schizophrenia", Schizophrenia Bulletin, 25, pp.173~182 (1999)
  2. Babikian, T., "Sensitivity and specificity of various digit span scores in the detection of suspect effort", The Clinical Neuropsychologist, 20, pp.145~159 (2006)
  3. Baddeley, A., "Working Memory", Science, 255, pp.556~559 (1992)
  4. Barch, D. M., "Cognition in schizophrenia : Core psychological and neural mechanisms", Trends in Cognitive Sciences, 16, pp.27~34 (2012)
  5. Bark, N., "The impact of cognitive remediation on psychiatric symptoms of schizophrenia", Schizophrenia Research, 63, pp.229~235 (2003)
  6. Belchior, P., "Video game training to improve selective visual attention in older adults", Computers in Human Behavior, 29, pp.1318~1324 (2013)
  7. Bozikas, V. P., "Neuropsychological profile of cognitively impaired patients with schizophrenia", Comprehensive Psychiatry, 47, pp.136~143 (2006)
  8. Bracy, O. L., "PSS CogReHab visuospatial manual" (1994), Psychological Software Services Inc
  9. Braff, D. L., "Information processing and attention dysfunctions in schizophrenia", Schizophrenia Bulletin, 19, pp.233~259 (1993)
  10. Brendon, W. K., "Deficient visual sensitivity in schizotypal personality disorder", Schizophrenia Research, 127, pp.144~150 (2011)
  11. Brenner, C. A., "Visual processing and neuropsychological function in schizophrenia and schizoaffective disorder", Psychiatry Research, 111, pp.125~136 (2002)
  12. Brittain, P., "Visual processing, social cognition and functional outcome in schizophrenia", Psychiatry Research, 178, pp.270~275 (2010)
  13. Butler, P. D., "Visual perception and its impairment in schizophrenia", Biological Psychiatry, 64, pp.40~47 (2008)
  14. Butler, P. D., "Early-stage visual processing and cortical amplification deficits in schizophrenia", Archives of General Psychiatry, 62, pp.495~504 (2005)
  15. Calvert, G. A., "Activation of auditory cortex during silent lipreading", Science, 276, pp.593~596 (1997)
  16. Cannon, T. D., "Dorsolateral prefrontal cortex activity during maintenance and manipulation of information in working memory in patients with schizophrenia", Archives of General Psychiatry, 62, pp.1071~1080 (2005)
  17. Cappe, C., "Cognitive disorganisation in schizotypy is associated with deterioration in visual backward masking", Psychiatry Research, 200, pp.652~659 (2012)
  18. Cavallaro, R., "Computer-aided neurocognitive remediation as an enhancing strategy for schizophrenia rehabilitation", Psychiatry Research, 169, pp.191~196 (2009)
  19. Chan, J. Y. C., "Can computer-assisted cognitive remediation improve employment and productivity outcomes of patients with severe mental illness? A meta-analysis of prospective controlled trials", Journal of Psychiatric Research, 68, pp.293~300 (2015)
  20. Chen, Y., "Bipolar and schizophrenic patients differ in patterns of visual motion discrimination", Schizophrenia Research, 88, pp.208~216 (2006)
  21. Chey, J., "Spatial working memory span, delayed response and executive function in schizophrenia", Psychiatry Research, 110, pp.259~271 (2002)
  22. 조수진, "정신분열병 환자에 대한 인지재활 훈련이 신경인지기능과 사회적 기능에 미치는 효과", Korean Journal of Clinical Psychology, 23(3), pp.559~576 (2004), 한국임상심리학회[DOI]
  23. Cicerone, K. D., "Evidence-based cognitive rehabilitation : Recommendations for clinical practice", Archives of Physical Medicine and Rehabilitation, 81, pp.1596~1615 (2000)
  24. Conklin, H. M., "Verbal working memory impairment in schizophrenia patients and their first-degree relatives : Evidence from the digit span task", The American Journal of Psychiatry, 157, pp.275~277 (2000)
  25. Couture, S. M., "The functional significance of social cognition in schizophrenia : A review", Schizophrenia Bulletin, 32, pp.44~63 (2006)
  26. De Lisi, R., "Improving children’s mental rotation accuracy with computer game playing", Journal of Genetic Psychology, 163, pp.272~282 (2002)
  27. Dixit, A., "Cognitive dysfunction in schizophrenia", Indian Journal of Health and Wellbeing, 7, pp.177~185 (2016)
  28. Eisen, S. V., "Reliability and validity of a brief patient-report instrument for psychiatric outcome evaluation", Psychiatric Services, 45, pp.242~247 (1994)
  29. Fioravanti, M., "A meta-analysis of cognitive deficits in adults with a diagnosis of schizophrenia", Neuropsychological Review, 15, pp.73~95 (2005)
  30. Fleming, K., "Visuospatial working memory in patients with schizophrenia", Society of Biological Psychiatry, 41, pp.43~49 (1997)
  31. Franck, N., "Specific vs general cognitive remediation for executive functioning in schizophrenia : A multicenter randomized trial", Schizophrenia Research, 147, pp.68~74 (2013)
  32. Gharaeipour, M., "Effects of cognitive remediation on neurocognitive functions and psychiatric symptoms in schizophrenia inpatients", Schizophrenia Research, 142, pp.156~170 (2012)
  33. Green, C. S., "Effect of action video games on the spatial distribution of visuospatial attention", Journal of Experimental Psychology : Human Perception and Performance, 32, pp.1465~1478 (2006)
  34. Green, M. F., "Should schizophrenia be treated as a neurocognitive disorder?", Schizophrenia Bulletin, 25, pp.309~318 (1999)
  35. Haenschel, C., "Cortical oscillatory activity is critical for working memory as revealed by deficits in early-onset schizophrenia", Journal of Neuroscience, 29, pp.9481~9489 (2009)
  36. Hale, J. B., "Analyzing digit span components for assessment of attention processes", Journal of Psychoeducational Assessment, 20, pp.128~143 (2002)
  37. Harvey, P. D., "Cognitive functioning in schizophrenia : A consensus statement on its role in the definition and evaluation of effective treatments for the illness", Journal of Clinical Psychiatry, 65, pp.361~372 (2004)
  38. Heaton, R. K., "Wisconsin Card Sorting Test manual: Revised and expanded" (1993), Psychological Assessment Resources
  39. Hiatt, K. D., "Stroop tasks reveal abnormal selective attention among psychopathic offenders", Neuropsychology, 18, pp.50~59 (2004)
  40. Hoffmann, F. L., "Measuring treatment outcome for adults and adolescent : Reliability and validity of BASIS-32", Journal of Mental Health Administration, 24, pp.316~331 (1997)
  41. Hogarty, G. E., "Cognitive enhancement therapy for schizophrenia : Effects of a 2-year randomized trial on cognition and behavior", Archives of General Psychiatry, 61, pp.866~876 (2004)
  42. Hwang, S. T., "Korean-Wechsler Adult Intelligence Scale-IV manual" (2012), Korea Psychology Co
  43. Hwang, T. Y., "A study on the validity and reliability of the korean version of behavior and symptom identification scale(BASIS-32)", Yong-In Psychiatry Bulletin, 7, pp.49~60 (2000)
  44. 장희진, "전산화 주의 재활 훈련이 정신분열병 환자의 인지 기능에 미치는 효과", Korean Journal of Clinical Psychology, 30(3), pp.803~823 (2011), 한국임상심리학회[DOI]
  45. Javitt, D. C., "When doors of perception close : Bottom-up models of disrupted cognition in schizophrenia", Annual Review of Clinical Psychology, 5, pp.249~275 (2009)
  46. Johnson, S. C., "Global-local visual processing in schizophrenia : Evidence for an early visual processing deficit", Society of Biological Psychiatry, 58, pp.937~946 (2005)
  47. Kanwisher, N., "Visual attention : Insights from brain imaging", Neuroscience, 1, pp.91~100 (2000)
  48. Kay, H. R., "The positive and negative syndrome scale(PANSS)for schizophrenia", Schizophrenia Bulletin, 13, pp.261~276 (1987)
  49. Kent, B. W., "Deficient visual sensitivity in schizotypal personality disorder", Schizophrenia Research, 127, pp.144~150 (2011)
  50. Kim, J., "Maintenance and manipulation of information in schizophrenia : Further evidence for impairment in the central executive component of working memory", Schizophrenia Research, 68, pp.178~187 (2004)
  51. Kim, J. K., "Korean-California verbal learning test(K-CVLT) : A normative study", Korean Journal of Clinical Psychology, 16, pp.379~395 (1997)
  52. 김명선, "시공간 재활 훈련이 정신분열병 환자의 인지 기능에 미치는 효과", Korean Journal of Clinical Psychology, 27(1), pp.51~68 (2008), 한국임상심리학회[DOI]
  53. Koychev, I., "Visual information processing deficits as biomarkers of vulnerability to schizophrenia : An event-related potential study in schizotypy", Neuropsychologia, 48, pp.2205~2214 (2010)
  54. Kurtz, M. M., "Symptoms versus neurocognition as predictors of change in life skills in schizophrenia after outpatient rehabilitation", Schizophrenia Research, 102, pp.303~311 (2008)
  55. Kurylo, D. D., "Perceptual organization by proximity and similarity in schizophrenia", Schizophrenia Research, 95, pp.205~214 (2007)
  56. Lee, T. M., "The relationship between visual-preception and attention in Chinese with schizophrenia", Schizophrenia Research, 72, pp.185~193 (2005)
  57. Lezak, M., "Neuropsychological assessment" (1995), OUP
  58. Luck, S. J., "The construct of attention in schizophrenia", Biological Psychiatry, 64, pp.34~39 (2008)
  59. MacLeod, C. M., "The stroop task : The"gold standard"of attentional measures", Journal of Experimental Psychology: General, 121, pp.12~14 (1992)
  60. Marder, S. R., "Initiatives to promote the discovery of drugs to improve cognitive function in severe mental illness", Journal of Clinical Psychiatry, 67, pp.31~35 (2006)
  61. McCrea, S. M., "Visual Puzzles, figure weights, and cancellation : Some preliminary hypotheses on the functional and neural substrates of these three new WAIS-IV subtests", International Scholarly Research Network Neurology, 2011, pp.1~19 (2011)
  62. McGurk, S. R., "A meta-analysis of cognitive remediation in schizophrenia", American Journal of Psychiatry, 164, pp.1791~1802 (2007)
  63. Medalia, A., "The remediation of problem-solving skills in schizophrenia", Schizophrenia Bulletin, 27, pp.259~267 (2001)
  64. Meyer, J., "Rey complex figure and recognition trial : Professional manual" (1995), Psychological Assessment Resources
  65. Milner, B., "Interhemispheric differences in the localization of psychological processes in man", Interhemispheric Differences and Psychological Processes, 27, pp.272~277 (1971)
  66. Ogino, T., "Predicting executive function task scores with the Rey-Osterrieth Complex Figure", Brain & Development, 31, pp.52~57 (2009)
  67. Okagaki, L., "Effects of video game playing on measures of spatial performance : Gender effects in late adolescence", Journal of Applied Developmental Psychology, 15, pp.33~58 (1994)
  68. Osterrieth, P. A., "The test of copying a complex figure : A contribution to the study of perception and memory", Archives of Psychology, 30, pp.286~350 (1994)
  69. Park, H. J., "The relationship between visuospatial function and attention in chronic schizophrenia patients", 석사, pp.2007
  70. 박주현, "전산화 집행 기능 재활이 조현병 환자의 인지 기능 향상에 미치는 효과", Korean Journal of Clinical Psychology, 34(1), pp.37~60 (2015), 한국임상심리학회[DOI]
  71. 박윤정, "주의력 재활 훈련이 정신분열병 환자의 인지 기능에 미치는 효과", Korean Journal of Clinical Psychology, 24(4), pp.721~737 (2005), 한국임상심리학회
  72. Penade's, R., "Cognitive mechanisms, psychosocial functioning, and neurocognitive rehabilitation in schizophrenia", Schizophrenia Research, 63, pp.219~227 (2003)
  73. Poirel, N., "Meaningfulness and global-local processing in schizophrenia", Neuropsychologia, 48, pp.3062~3068 (2010)
  74. Posner, M. I., "Attention and primary visual cortex", Proceeding of the National Academy of Sciences, 96, pp.2585~2587 (1999)
  75. Rey, A., "L’examine psychologique dans les cas d’encephalophathie traumatique", Archives de Psychologie, 28, pp.286~340 (1941)
  76. Roder, V., "Effectiveness of integrated psychological therapy for schizophrenia patients : A research update", Schizophrenia Bulletin, 37, pp.71~79 (2011)
  77. Rönnlund, M., "Adult life-span patterns in WAIS-R block design performance : Cross-sectional versus longitudinal age gradients and relations to demographic factors", Intelligence, 34, pp.63~78 (2006)
  78. Rosenthal, E. N., "Digit span components as predictors of attention problems and executive functioning in children", Archives of Clinical Neuropsychology, 21, pp.131~139 (2006)
  79. Rund, B. R., "Cognitive deficits and cognitive training in schizophrenic patients : A review", Acta Psychiatrica Scandinavica, 100, pp.85~95 (1999)
  80. Santosh, S., "Psychopathology, cognitive function, and social functioning of patients with schizophrenia", East Asian Arch Psychiatry, 23, pp.65~70 (2013)
  81. Schechter, I., "Magnocellular and parvocellular contributions to backward masking dysfunction in schizophrenia", Schizophrenia Research, 64, pp.91~101 (2003)
  82. Sehatpour, P., "Impaired visual object processing across an occipital-frontal-hippocampal brain network in schizophrenia : An integrated neuroimaging study", Archives of General Psychiatry, 67, pp.772~782 (2010)
  83. Seidman, L. J., "Organizational and visual memory deficits in schizophrenia and bipolar psychoses using the rey-osterrieth complex figure : Effects of duration of illness", Journal of Clinical and Experimental Neuropsychology, 25, pp.949~964 (2003)
  84. Sergi, M. J., "Social perception and early visual processing in schizophrenia", Schizophrenia Research, 59, pp.233~241 (2002)
  85. Sergi, M. J., "Social perception as a mediator of the influence of early visual processing on functional status in schizophrenia", The American Journal of Psychiatry, 163, pp.448~454 (2006)
  86. Sergi, M. J., "Social cognition in schizophrenia : Relationships with neurocognition and negative symptoms", Schizophrenia Research, 90, pp.316~324 (2007)
  87. Silverstein, A. B., "Agreement between a short-form and full scale as a function of the correlation between them", Journal of Clinical Psychology, 45, pp.929~931 (1989)
  88. Song, Y. W., "The effect of computerized cognition program (RehaCom)on the improvement of cognitive functions in patients with schizophrenia", The Journal of Korean Society of Cognitive Rehabilitation, 4, pp.65~79 (2015)
  89. Stroop, J. R., "Studies of interference in series verbal reactions", Journal of Experimental Psychology, 18, pp.643~662 (1935)
  90. Sullivan, E. V., "The contribution of constructional accuracy and organizational strategy to nonverbal recall in schizophrenia and chronic alcoholism", Biological Psychiatry, 32, pp.312~333 (1992)
  91. Surti, T. S., "Successful computer-based visual training specifically predicts visual memory enhancement over verbal memory improvement in schizophrenia", Schizophrenia Research, 132, pp.131~134 (2011)
  92. Tan, H. M., "High-frequency neural oscillations and visual processing deficits in schizophrenia", Frontiers in Psychology, 621, pp.1~19 (2013)
  93. Wykes, T., "A meta-analysis of cognitive remediation for schizophrenia : Methodology and effect sizes", American Journal of Psychiatry, 168, pp.472~485 (2011)
  94. Wykes, T., "Cognitive remediation therapy(CRT)for young early onset patients with schizophrenia : An exploratory randomized controlled trial", Schizophrenia Research, 94, pp.221~230 (2007)
  95. Yum, T. H., "Korean-Wechsler Adult Intelligence Scale manual" (1992), Korea Guidance

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