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전계효과트랜지스터(FET) 바이오센서 실험 셋업 분석을 통한 동작원리 이해

Understanding of the Working Principle of Field-effect Transistor (FET) Biosensor with the Review Of Experimental Measurement Set-up

이국녕
한국센서학회|2023.11|센서학회지 (Journal of Sensor Science and Technology)|제32권 제6호|pp. 487-495|DOI http://dx.doi.org/10.46670/JSST.2023.32.6.487

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Field-effect transistor(FET) biosensorElectrochemical sensingElectrochemical sensor read-outFake response
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초록

Over the past few decades, considerable research has been conducted on field-effect transistor (FET) biosensors; however,other than electrochemical sensors for pH, they have not reached the commercialization stage and still remain at the basicresearch level. Although several reports have been published on experiments with real biological samples, no reports exist ofdevelopments that have reached commercialization or finalized approval for use. In this paper, we explain the reason for theexperiments of FET biosensors to induce spurious signals in an experimental setup and explain the existence of misunderstandingsregarding the operating principle of FET biosensors owing to the spurious signals. Based on the thoughtfulreview of the results of previously published papers, we show that the electrochemical read-out principle of FET biosensorsrequires our intensive understanding of the interfacial potential between the solution and the sensor electrode for further progressin the FET biosensor research.

Abstract

Over the past few decades, considerable research has been conducted on field-effect transistor (FET) biosensors; however,other than electrochemical sensors for pH, they have not reached the commercialization stage and still remain at the basicresearch level. Although several reports have been published on experiments with real biological samples, no reports exist ofdevelopments that have reached commercialization or finalized approval for use. In this paper, we explain the reason for theexperiments of FET biosensors to induce spurious signals in an experimental setup and explain the existence of misunderstandingsregarding the operating principle of FET biosensors owing to the spurious signals. Based on the thoughtfulreview of the results of previously published papers, we show that the electrochemical read-out principle of FET biosensorsrequires our intensive understanding of the interfacial potential between the solution and the sensor electrode for further progressin the FET biosensor research.

참고문헌 (42)

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