자금정의 아토피피부염 치료 효과에 대한 환자군 연구
Case Series Study about the Effect of Jageum-Jung on Atopic Dermatitis
2
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Objectives The purpose of this study is to analyze the clinical data of atopic dermatitis patients and to report the therapeutic effect of Jageum-Jung. Methods We conducted a retrospective study on the effects of treatment on atopic dermatitis patients who took Jageum-Jung from August 1, 2017 to December 20, 2017. The patients visited three times during the treatment period. The SCORAD Index score was measured and analyzed. Results Atopic dermatitis patients were 2 adults and 5 children. Both 2 adults were male (100%). Among the children, 1 child was a male (20%) and 4 children were females (80%). For adults, average age was 29.5 years, average weight was 72.75 kg, average height was 1.76 m and average BMI was 23.49 kg/m2. For children, average age was 6.2 years, average weight was 23.92 kg, average height was 1.2 m and average BMI was 16.08 kg/m2. The atopic dermatitis patients’ average SCORAD Index score was 18.04 at first visit, 11.46 at second visit, and 7.64 at third visit. The scores lowered significantly after every visit. Conclusions The SCORAD Index in atopic dermatitis patients who took Jageum-Jung significantly decreased and it is expected that Jageum-Jung will be clinically effective in the treatment of atopic dermatitis.
Abstract
Objectives The purpose of this study is to analyze the clinical data of atopic dermatitis patients and to report the therapeutic effect of Jageum-Jung. Methods We conducted a retrospective study on the effects of treatment on atopic dermatitis patients who took Jageum-Jung from August 1, 2017 to December 20, 2017. The patients visited three times during the treatment period. The SCORAD Index score was measured and analyzed. Results Atopic dermatitis patients were 2 adults and 5 children. Both 2 adults were male (100%). Among the children, 1 child was a male (20%) and 4 children were females (80%). For adults, average age was 29.5 years, average weight was 72.75 kg, average height was 1.76 m and average BMI was 23.49 kg/m2. For children, average age was 6.2 years, average weight was 23.92 kg, average height was 1.2 m and average BMI was 16.08 kg/m2. The atopic dermatitis patients’ average SCORAD Index score was 18.04 at first visit, 11.46 at second visit, and 7.64 at third visit. The scores lowered significantly after every visit. Conclusions The SCORAD Index in atopic dermatitis patients who took Jageum-Jung significantly decreased and it is expected that Jageum-Jung will be clinically effective in the treatment of atopic dermatitis.
참고문헌 (34)
- Park ID, "A literal study of anti-tumor effects of Jakeumjung", J Haehwa Med, 10(2), pp.73~81 (2002)
- Ren M, "The observation of the efficacy of using purple tablets on the patients with subcutaneous ecchymosis at the puncture site after coronary angiography or percutaneous coronary intervention", J Guangzhou Med, 43(4), pp.65~67 (2012)
- Xie X, "Application research of topical drugs in combination with hirudoid in hemodialysis puncture hematoma", China Med Herald, 40(6), pp.493~494 (2016)
- 조영기, "紫金錠이 간암세포주 HepG2의 세포고사 및 세포주기에 미치는 영향", 대한한방내과학회지, 28(4), pp.694~708 (2007), 대한한방내과학회
- Lee MS, "A literature review on the detoxifying effect of Jakeumjung", J East-West Med, 4(3), pp.34~37 (1979)
- Engel-Yeger B, "Sensory processing patterns of adults with atopic dermatitis", J Eur Acad Dermatol Venereol, 25(2), pp.152~156 (2011)[DOI]
- 김기영, "아토피 피부염의 한의학적 치료에 대한 연구 동향 -대한한방소아과학회지를 중심으로-", 대한한방소아과학회지, 31(1), pp.25~42 (2017), 대한한방소아과학회
- 김지수, "生料四物湯이 DNCB로 유발된 생쥐의 아토피 피부염에 미치는 영향", 한방안이비인후피부과학회지, 30(1), pp.87~105 (2017), 대한한방안이비인후피부과학회
- 박양, "한국에서 아토피피부염 진단과 치료의 임상적 실태 조사", Allergy Asthma & Respiratory Disease, 1(3), pp.257~265 (2013), 대한 소아알레르기 호흡기학회
- 조아라, "중증 아토피피부염 환자 89명의 한의학적 치료 효과에 대한 후향적 연구", 한방안이비인후피부과학회지, 29(2), pp.161~179 (2016), 대한한방안이비인후피부과학회[DOI]
- Schmitt J, "Assessment of clinical signs of atopic dermatitis: a systematic review and recommendation", J Allergy Clin Immunol, 132(6), pp.1337~1347 (2013)[DOI]
- Odhiambo JA, "Global variations in prevalence of eczema symptoms in children from ISAAC phase three", J Allergy Clin Immunol, 124(6), pp.1251~1258 (2009)[DOI]
- Guttman-Yassky E, "Contrasting pathogenesis of atopic dermatitis and psoriasis-part I: clinical and pathologic concepts", J Allergy Clin Immunol, 127(5), pp.1110~1118 (2011)[DOI]
- Boguniewicz M, "Atopic dermatitis: a disease of altered skin barrier and immune dysregulation", Immunol Rev, 242(1), pp.233~246 (2011)[DOI]
- 서지혜, "加減淸營湯에 효과를 보인 열성 아토피 피부염 환자6례 증례 보고", 한방안이비인후피부과학회지, 27(3), pp.191~204 (2014), 대한한방안이비인후피부과학회
- 기호필, "黃連解毒湯의 아토피 피부염 개선 效果", 대한한의학 방제학회지, 21(1), pp.80~90 (2013), 대한한의학방제학회
- Wei X, "A study on the antibacterial effect of external application Jageum-Jung", J Chin Med Mater, 27(10), pp.761~762 (2004)
- 이현주, "Therapeutic Effects of Korean Red Ginseng Extract in a Murine Model of Atopic Dermatitis: Anti-pruritic and Anti-inflammatory Mechanism", Journal of Korean Medical Science, 32(4), pp.679~687 (2017), 대한의학회
- Totte J, "Targeted anti-staphylococcal therapy with endolysins in atopic dermatitis and the effect on steroid use, disease severity and the microbiome", Trials, 18(1), pp.404~ (2017)[DOI]
- Mendonca P, "The attenuating effects of 1,2,3,4,6-Penta-O-galloyl-<TEX>$\beta$<", TEX>-D-glucose on inflammatory cytokines release from activated BV-2 microglial cells, 2017, pp.305, 9~15
- 도은수, "오배자 발효추출물의 항세균활성", 대한본초학회지, 29(4), pp.21~27 (2014), 대한본초학회
- 조홍석, "오배자, 우슬, 가자 및 감초를 포함하는 혼합추출물의 항산화 및 항균활성", KSBB Journal, 29(1), pp.29~35 (2014), 한국생물공학회
- 유진곤, "口瘡의 外用藥으로 多用되는 黃柏, 靑黛, 白礬 및 五倍子의 抗炎作用에 관한 硏究", 한방안이비인후피부과학회지, 18(1), pp.183~198 (2005), 대한한방안이비인후피부과학회
- Liu L, "Five new biphenanthrenes from Cremastra Appendiculata", Molecules, 21(8), pp.1089~ (2016)[DOI]
- Kong LY, "Cytotoxic diterpenoids from Euphorbia Pekinensis", Planta Med, 68(3), pp.249~252 (2002)[DOI]
- 조유란, "아토피유발인자 억제효과를 증대하는 Lactococcus lactis의 배양방법", 한국미생물·생명공학회지, 40(4), pp.310~318 (2012), 한국미생물·생명공학회[DOI]
- Kim CT, "Inhibitors of melanogenesis from Euphorbiae Lathyridis Semen", J Kor Pharmacogn, 31(2), pp.168~173 (2000)
- 서기석, "The Inhibitory Effect of Phytoclear-EL1 on Melanogenesis", Annals of Dermatology, 21(4), pp.369~375 (2009), 대한피부과학회
- Liang QQ, "Muscone protects vertebral end-plate degeneration by antiinflammatory property", Clin Orthop Relat Res, 468(6), pp.1600~1610 (2010)[DOI]
- Eiji Inoue, "Agarwood Inhibits Histamine Release from Rat Mast Cells and Reduces Scratching Behavior in Mice -Effect of Agarwood on Histamine Release and Scratching Behavior-", Journal of Pharmacopuncture, 19(3), pp.239~245 (2016), 대한약침학회[DOI]
- 김민섭, "자외선A로 손상된 DNA의 회복과 DNCB에 의한 알러지성 접촉피부염에 대한 표고버섯과 침향 추출 혼합물의 효과", 한국식품영양학회지, 28(5), pp.759~765 (2015), 한국식품영양학회
- Canli K, "In vitro antimicrobial screening of Aquilaria Agallocha roots", Afr J Tradit Complement Altern Med, 13(5), pp.178~181 (2016)
- 임희진, "한국인 소아기 및 성인기 아토피피부염 역학조사를 위한 진단적 설문지", 대한피부과학회지, 46(11), pp.1495~1499 (2008), 대한피부과학회
- Peters AS, "Prediction of the incidence, recurrence, and persistence of atopic dermatitis in adolescence: a prospective cohort study", J Allergy Clin Immunol, 126(3), pp.590~595 (2010)[DOI]
