內消和中湯加味方의 아토피 피부염 치료에 대한 임상고찰

Abstract

Objective : The objective of this study is to assess the clinical effect of Naesowhajungtang Gamibang on atopic dermatitis. Method : A total of 30 patients with atopic dermatitis were evaluated for the symptoms and signs according to SCORAD index and measured for peripheral eosinophil counts and serum total IgE before and after treatment. Results : 1.Among 30 patients diagnosed as Atopic Dermatitis, 11 were male(37%) and 19 were female(63%). The ratio of male and female patients were 1:1.7. 2.Among 30 patients diagnosed as Atopic Dermatitis, 25 have family history of allergic disease(83%) and 20 have past history of allergic disease(67%). 3.There was statistically significant relationship between serum total IgE and SCORAD score(p=0.019). 4.There was statistically significant relationship between peripheral eosinophil count and SCORAD score(p=0.001). 5.We could find no statistically significant change of serum total IgE and peripheral eosinophil count before and after treatment. 6.There was statistically significant change of SCORAD score and subjective symptom before and after treatment.(p<0.05). Conclusion : Naesowhajungtanggamibang is effective in the treatment of atopic dermatitis. And peripheral eosinophil counts and serum total IgE were good serum marker reflecting the severity of atopic dermatitis