국소한약외용제의 알레르기성 비염 치료 효과에 대한 문헌 고찰
A Literature Study of Topical Application of Chinese Herbal Medicine for Allergic Rhinitis
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초록
Objectives The purpose of this study is to analyze studies about the effects of topical application of Chinese herbal medicine for allergic rhinitis within randomized controlled trials (RCT). Methods The search database includes KJTK (Korean Traditional Knowledge Portal), OASIS (Oriental Medicine Advanced Searching Integrated system), CNKI (China National Knowledge Infrastructure), PubMed, and EMBASE. We used the following key search terms: “allergic rhinitis”, “traditional Chinese medicine”, “traditional Korean medicine”, “Chinese herbal medicine”, “randomized controlled trial”, “clinical study”, “nasal spray”, and “nasal drop” Results Five studies were selected for analysis. Three studies used nasal spray of Chinese herbal medicine and two studies used nasal drops of Chinese herbal medicine for the intervention. Frequently used herbs were Magnoliae Flos (辛夷), Scutellariae Radix (黃芩), Coptidis Rhizoma (黃連), and Astragali Radix (黃芪). For the outcome measures, studies used symptom score, questionnaire of Quality of Life, nasal airway resistance, or laboratory studies. From all 5 studies, it has been shown that topical application of Chinese herbal medicine was effective for improving symptoms of allergic rhinitis. Two out of five studies showed statistical difference between study group and control group. Conclusions This study shows that topical application of Chinese herbal medicine can improve symptoms of allergic rhinitis. Well-designed RCT studies with low risk of bias and studies with outcome measures for assessing the immunomodulatory effects are necessary to confirm these findings.
Abstract
Objectives The purpose of this study is to analyze studies about the effects of topical application of Chinese herbal medicine for allergic rhinitis within randomized controlled trials (RCT). Methods The search database includes KJTK (Korean Traditional Knowledge Portal), OASIS (Oriental Medicine Advanced Searching Integrated system), CNKI (China National Knowledge Infrastructure), PubMed, and EMBASE. We used the following key search terms: “allergic rhinitis”, “traditional Chinese medicine”, “traditional Korean medicine”, “Chinese herbal medicine”, “randomized controlled trial”, “clinical study”, “nasal spray”, and “nasal drop” Results Five studies were selected for analysis. Three studies used nasal spray of Chinese herbal medicine and two studies used nasal drops of Chinese herbal medicine for the intervention. Frequently used herbs were Magnoliae Flos (辛夷), Scutellariae Radix (黃芩), Coptidis Rhizoma (黃連), and Astragali Radix (黃芪). For the outcome measures, studies used symptom score, questionnaire of Quality of Life, nasal airway resistance, or laboratory studies. From all 5 studies, it has been shown that topical application of Chinese herbal medicine was effective for improving symptoms of allergic rhinitis. Two out of five studies showed statistical difference between study group and control group. Conclusions This study shows that topical application of Chinese herbal medicine can improve symptoms of allergic rhinitis. Well-designed RCT studies with low risk of bias and studies with outcome measures for assessing the immunomodulatory effects are necessary to confirm these findings.
참고문헌 (28)
- Hong CE, "Textbook of pediatrics", pp.1144~1150 (2012), Miraen Publising co
- Kim KB, "Pediatrics of Korean medicine. First Volume", pp.359~360 (2015), Eui Seong Dang Publishing co
- Schatz M, "A survey of the burden of allergic rhinitis in the USA", Allergy, 62(Suppl85), pp.9~16 (2007)
- Ozdoganoglu T, "Quality of life in allergic rhinitis", Ther Adv Respir Dis, 6(1), pp.25~39 (2012)
- Pawankar R, "Allergic rhinitis and its impact on asthma in Asia pacific and the ARIA update 2008", World Allergy Organ J, 5(Suppl 3), pp.S212~S217 (2008)
- Huang TP, "A nationwide population-based study of traditional Chinese medicine usage in children in Taiwan", Complement Ther Med, 22(3), pp.500~510 (2014)
- Li XM, "Complementary and alternative medicine in pediatric allergic disorders", Curr Opin Allergy Clin Immunol, 9(2), pp.161~167 (2009)
- Yen HR, "Characteristics of traditional Chinese medicine use for children with allergic rhinitis: a nationwide population- based study", Int J Pediatr Otorhinolaryngol, 79(4), pp.591~597 (2015)
- Feng S, "Acupuncture for the treatment of allergic rhinitis: a systematic review and meta-analysis", Am J Rhinol Allergy, 29(1), pp.57~62 (2015)
- Wen CY, "A systematic and narrative review of acupuncture point application therapies in the treatment of allergic rhinitis and asthma during dog days", Evid Based Complement Alternat Med: eCAM, 2015, pp.846~851 (2015)
- Wu M, "Clinical observation of Flos Magnoliae Volatile oil nano-liposome nasal drops in treating pediatric allergic rhinitis", Zhongguo Zhong Xi Yi Jie He Za Zhi, 29(8), pp.740~742 (2009)
- Chui SH, "A panel study to evaluate quality of life assessments in patients suffering from allergic rhinitis after treatment with a Chinese herbal nasal drop", Phytother Res, 24(4), pp.609~613 (2010)
- Chen XX, "Clinical study of curing patients with perennial allergic rhinitis by Qumin Tongbi nasal spraying agent", Zhongguo Zhong Xi Yi Jie He Za Zhi, 31(5), pp.643~646 (2011)
- Yuan HX, "Clinical rsearch of Xinxiang Penbi Nanoemulsion in the treatment of pediatric allergic rhinitis", pp.2015
- Xiong Y, "Clinical research of Qu Min nasal spray in the treatment of allergic rhinitis", J Practic Tradit Chin Med, 31(04), pp.330~331 (2015)
- Lisa MW, "Allergic rhinitis", N Engl J Med, 372(5), pp.456~463 (2015)
- "Korean Statistical Information Service" (2016)[URL]
- Denis K, "Treatment of allergic rhinitis", Am Fam Physician, 12(81), pp.1440~1446 (2010)
- Zhang Hl, "Bibliometric analysis on randomized controlled research literatures about treating allergic rhinitis with external therapy of traditional Chinese medicine", China J Tradit Chin Med Pharm, 30(9), pp.3247~3249 (2015)
- Lee JA, "Asiasari sieboldii suppresses inflammatory mediators through the induction of hemeoxygenase-1 expression in RAW264.7 cells", Immunopharmacol Immunotoxicol, 34(1), pp.15~20 (2012)
- Jung KY, "Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia Fargesii", J Nat Prod, 61(6), pp.808~811 (1998)
- 김용준, "CD4+ Jurkat T 세포주에서 Th1과 Th2 사이토가인 조절에 미치는 황금 유래 Baicalin, Baicalein 및 Wogonin의 효과", 동의생리병리학회지, 19(4), pp.922~927 (2005), 한의병리학회
- 이전우, "黃連 추출물의 항염효능에 관한 연구", 대한본초학회지, 29(5), pp.83~90 (2014), 대한본초학회
- 신상우, "대표적 보기약인 인삼, 당삼, 황기, 백출, 산약 물추출액의 면역조절효과 비교", 동의생리병리학회지, 18(4), pp.1140~1146 (2004), 한의병리학회
- Koo JS, "A clinical study on the effect of Tongkyu-tang distillate on pediatric allergic rhinitis", J Korean Orient Pediatr, 17(2), pp.103~114 (2003)
- 김지은, "만성 비염 환자의 한방코분무제에 대한 효과 및 만족도 조사", 한방안이비인후피부과학회지, 25(3), pp.56~64 (2012), 대한한방안이비인후피부과학회[DOI]
- 김민애, "세신고가 알레르기성 비염에 미치는 효과", 한방안이비인후피부과학회지, 21(3), pp.69~81 (2008), 대한한방안이비인후피부과학회
- 구은진, "알레르기성 비염의 한의학 및 보완대체의학적 치료에 대한 국내 임상 연구 동향", 대한한방소아과학회지, 29(4), pp.77~89 (2015), 대한한방소아과학회